Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer (Q34813272)

4 August 2017

title

Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer (English)

1 reference

4 August 2017

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Frédérique Penault-Llorca

4 August 2017

Frédérique Penault-Llorca

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Nicola Aceto

Nicola Aceto

Nerissa Therese Viola-Villegas

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ORCID Public Data File 2021

Nerissa Therese Viola-Villegas

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Pau Castel

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Borivoj Vojnovic

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Tony Ng

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Paul Barber

1 reference

Shyamala Maheswaran

Shyamala Maheswaran

1 reference

4 August 2017

Jessica J Tao

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4 August 2017

Nina Radosevic-Robin

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4 August 2017

Moshe Elkabets

1 reference

4 August 2017

Neil Auricchio

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4 August 2017

Gregory Weitsman

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4 August 2017

Haley Ellis

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4 August 2017

Natasha Morse

1 reference

4 August 2017

Ana Bosch

1 reference

4 August 2017

Dejan Juric

1 reference

4 August 2017

Saswati Hazra

1 reference

4 August 2017

Sharat Singh

1 reference

4 August 2017

Phillip Kim

1 reference

4 August 2017

Anna Bergamaschi

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4 August 2017

Jason S Lewis

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4 August 2017

Lisa A Carey

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4 August 2017

José Baselga

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4 August 2017

Maurizio Scaltriti

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4 August 2017

publication date

25 March 2014

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4 August 2017

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4 August 2017

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4 August 2017

issue

318

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4 August 2017

page(s)

ra29

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Applying PET to broaden the diagnostic utility of the clinically validated CA19.9 serum biomarker for oncology

4 August 2017

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Highly sensitive proximity mediated immunoassay reveals HER2 status conversion in the circulating tumor cells of metastatic breast cancer patients

8 July 2018

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Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors

8 July 2018

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mTOR kinase inhibition causes feedback-dependent biphasic regulation of AKT signaling

8 July 2018

1 reference

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A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies

8 July 2018

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Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase

8 July 2018

1 reference

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PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer

8 July 2018

1 reference

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Primary resistance to cetuximab in a panel of patient-derived tumour xenograft models: Activation of MET as one mechanism for drug resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283215

AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activity

8 July 2018

1 reference

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Triple-Negative Breast Cancer

8 July 2018

1 reference

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Isolation of circulating tumor cells using a microvortex-generating herringbone-chip

8 July 2018

1 reference

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Triple-negative breast cancer: disease entity or title of convenience?

8 July 2018

1 reference

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Kinase-mediated quasi-dimers of EGFR

8 July 2018

1 reference

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The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress.

8 July 2018

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Standardized methods for the production of high specific-activity zirconium-89.

8 July 2018

1 reference

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Inhibitor hijacking of Akt activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283215

Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells

8 July 2018

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The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer

8 July 2018

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Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members

8 July 2018

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Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3

8 July 2018

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Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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21 January 2018

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21 January 2018

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Computational modeling of ERBB2-amplified breast cancer identifies combined ErbB2/3 blockade as superior to the combination of MEK and AKT inhibitors

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Pathologic response to induction chemotherapy in locally advanced carcinoma of the breast: a determinant of outcome

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24667376

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCISIGNAL.2005125

1 reference

release_7e5tftvtpjar5gpuoxtnbvd6cy

4 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7e5tftvtpjar5gpuoxtnbvd6cy

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4283215

1 reference

4 August 2017

1 reference