p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors. (Q34694274)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16714381%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors (English)

1 reference

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28 January 2020

1 reference

1 reference

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28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16714381%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Dennis R Roop

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16714381%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Maranke I Koster

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16714381%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Xuecui Guo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16714381%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Yi Qi

1 reference

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28 January 2020

Kristin M Petherbridge

1 reference

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28 January 2020

Allan Bradley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16714381%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Alea A Mills

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16714381%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

language of work or name

English

0 references

publication date

19 May 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16714381%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

28 January 2020

number of pages

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

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28 January 2020

volume

103

1 reference

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28 January 2020

issue

1 reference

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28 January 2020

page(s)

8435-8440

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16714381%20AND%20SRC:MED&resulttype=core&format=json

p63: a new link between senescence and aging

28 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

p63 deficiency activates a program of cellular senescence and leads to accelerated aging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

High-resolution genomic profiles of human lung cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

p63 and p73: roles in development and tumor formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

p63 and the epithelial stem cell: more than status quo?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

p63 is the molecular switch for initiation of an epithelial stratification program

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

Distribution of p63, cytokeratins 5/6 and cytokeratin 14 in 51 normal and 400 neoplastic human tissue samples using TARP-4 multi-tumor tissue microarray

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

Elevated expression of p63 protein in human esophageal squamous cell carcinomas

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

P63 in pulmonary epithelium, pulmonary squamous neoplasms, and other pulmonary tumors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

p63 expression in normal skin and usual cutaneous carcinomas

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

p63 expression profiles in human normal and tumor tissues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

Histologic and immunophenotypic classification of cervical carcinomas by expression of the p53 homologue p63: a study of 250 cases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

Expression of the p53 homologue p63 in early cervical neoplasia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

High level expression of deltaN-p63: a mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

AIS is an oncogene amplified in squamous cell carcinoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

p53 family genes: structural comparison, expression and mutation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

Mutation and transcription analyses of the p63 gene in cervical carcinoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

Mutational analysis of p51A/TAp63gamma, a p53 homolog, in non-small cell lung cancer and breast cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

p63 is a p53 homologue required for limb and epidermal morphogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

Cloning and functional analysis of human p51, which structurally and functionally resembles p53

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

Tumor spectrum analysis in p53-mutant mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

p53 mutations in human cancers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

Multistage carcinogenesis in mouse skin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602477103

Frequent gain of the p40/p51/p63 gene locus in primary head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602477103

Differential expression of p53 gene family members p63 and p73 in head and neck squamous tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602477103

The transactivating isoforms of p63 are overexpressed in high-grade follicular lymphomas independent of the occurrence of p63 gene amplification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602477103

Roles of p63 in the diethylstilbestrol-induced cervicovaginal adenosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602477103

Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602477103

p63 and p73 do not contribute to p53-mediated lymphoma suppressor activity in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602477103

Significance of p63 amplification and overexpression in lung cancer development and prognosis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482510

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

26 October 2018

2 references

https://api.crossref.org/works/10.1073%2FPNAS.0602477103

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/16714381

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

DeltaNp63 induces beta-catenin nuclear accumulation and signaling

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602477103

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602477103

Conditional inactivation of p63 by Cre-mediated excision

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0602477103

Expression of p73 and p63 proteins in pancreatic adenocarcinoma: p73 overexpression is inversely correlated with biological aggressiveness

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16714381

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0602477103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16714381%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16714381%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

16714381

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16714381%20AND%20SRC:MED&resulttype=core&format=json