Lack of interaction of milnacipran with the cytochrome p450 isoenzymes frequently involved in the metabolism of antidepressants (Q34650915)

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English	Lack of interaction of milnacipran with the cytochrome p450 isoenzymes frequently involved in the metabolism of antidepressants	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

16122284

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3 August 2017

title

Lack of interaction of milnacipran with the cytochrome p450 isoenzymes frequently involved in the metabolism of antidepressants (English)

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Europe PubMed Central

PubMed publication ID

16122284

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3 August 2017

author name string

Christian Puozzo

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1

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Europe PubMed Central

PubMed publication ID

16122284

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3 August 2017

Simone Lens

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2

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Europe PubMed Central

PubMed publication ID

16122284

retrieved

3 August 2017

Christian Reh

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3

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Europe PubMed Central

PubMed publication ID

16122284

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3 August 2017

Karl Michaelis

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4

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Europe PubMed Central

PubMed publication ID

16122284

retrieved

3 August 2017

Dominique Rosillon

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5

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Europe PubMed Central

PubMed publication ID

16122284

retrieved

3 August 2017

Xavier Deroubaix

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6

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Europe PubMed Central

PubMed publication ID

16122284

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3 August 2017

Dominique Deprez

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7

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Europe PubMed Central

PubMed publication ID

16122284

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3 August 2017

publication date

1 January 2005

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Europe PubMed Central

PubMed publication ID

16122284

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3 August 2017

published in

Clinical Pharmacokinetics

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Europe PubMed Central

PubMed publication ID

16122284

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3 August 2017

volume

44

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Europe PubMed Central

PubMed publication ID

16122284

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3 August 2017

issue

9

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Europe PubMed Central

PubMed publication ID

16122284

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3 August 2017

page(s)

977-988

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Europe PubMed Central

PubMed publication ID

16122284

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3 August 2017

cites work

The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes

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21 January 2018

Pharmacology and pharmacokinetics of milnacipran

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21 January 2018

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PubMed

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Polymorphic drug metabolism (CYP2D6) and utilisation of psychotropic drugs in hospitalised psychiatric patients: a retrospective study

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The effect of CYP2C19 and CYP2D6 genotypes on the metabolism of clomipramine in Japanese psychiatric patients

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12 December 2020

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Milnacipran plasma levels and antidepressant response in Japanese major depressive patients

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Integrated cytochrome P450 reaction phenotyping: attempting to bridge the gap between cDNA-expressed cytochromes P450 and native human liver microsomes

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Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine

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Inhibitory effects of tricyclic antidepressants (TCAs) on human cytochrome P450 enzymes in vitro: mechanism of drug interaction between TCAs and phenytoin

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Desipramine Pharmacokinetics When Coadministered With Paroxetine or Sertraline in Extensive Metabolizers

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12 December 2020

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Use of probe drugs as predictors of drug metabolism in humans

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12 December 2020

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Pharmacogenetic phenotyping and genotyping. Present status and future potential.

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12 December 2020

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Pharmacokinetics of milnacipran in liver impairment

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12 December 2020

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[Pharmacokinetics of second generation antidepressants]

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12 December 2020

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Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2.

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Genetic contribution to variable human CYP3A-mediated metabolism

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The effect of sertraline on the pharmacokinetics of desipramine and imipramine

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12 December 2020

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Lack of pharmacokinetic interaction when switching from fluoxetine to milnacipran

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12 December 2020

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Effects of Milnacipran and Pindolol on Extracellular Noradrenaline and Serotonin Levels in Guinea Pig Hypothalamus

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Selective serotonin reuptake inhibitors and cytochrome P-450 mediated drug-drug interactions: an update

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12 December 2020

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The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci

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12 December 2020

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Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19

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12 December 2020

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Identification of human cytochrome P450 isoforms involved in the stereoselective metabolism of mianserin enantiomers

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12 December 2020

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Inhibition of desipramine hydroxylation (Cytochrome P450-2D6) in vitro by quinidine and by viral protease inhibitors: relation to drug interactions in vivo

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

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Clinically relevant pharmacology of selective serotonin reuptake inhibitors. An overview with emphasis on pharmacokinetics and effects on oxidative drug metabolism

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoamine uptake inhibition by plasma from healthy volunteers after single oral doses of the antidepressant milnacipran

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

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Relationship between fluvoxamine pharmacokinetics and CYP2D6/CYP2C19 phenotype polymorphisms

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12 December 2020

based on heuristic

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Metabolism of the newer antidepressants. An overview of the pharmacological and pharmacokinetic implications

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12 December 2020

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Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva.

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12 December 2020

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Are all antidepressants the same?

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12 December 2020

based on heuristic

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Fatality associated with combined fluoxetine-amitriptyline therapy

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12 December 2020

based on heuristic

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Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan O-demethylation in different CYP2D6 genotypes

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12 December 2020

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Citalopram: interaction studies with levomepromazine, imipramine, and lithium

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12 December 2020

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S-mephenytoin hydroxylation phenotypes in a Swedish population determined after coadministration with debrisoquin

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Clinical efficacy of milnacipran: placebo-controlled trials.

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12 December 2020

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Newer antidepressants and the cytochrome P450 system

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https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

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Pharmacogenetics of antidepressants: clinical aspects

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PubMed

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12 December 2020

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Comparison of three CYP2D6 probe substrates and genotype in Ghanaians, Chinese and Caucasians

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1-Aryl-2-(aminomethyl)cyclopropanecarboxylic acid derivatives. A new series of potential antidepressants

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12 December 2020

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Comparative studies with milnacipran and tricyclic antidepressants in the treatment of patients with major depression: a summary of clinical trial results

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12 December 2020

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Ethnics differences in the reactions to drugs and xenobiotics. Antihypertensive agents

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

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Determination of milnacipran, a serotonin and noradrenaline reuptake inhibitor, in human plasma using liquid chromatography with spectrofluorimetric detection

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamics of milnacipran in young and elderly volunteers

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo inhibition of CYP2C19 but not CYP2D6 by fluvoxamine

1 reference

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PubMed

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12 December 2020

based on heuristic

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Quantitative determination by HPLC of urinary 6?-hydroxycortisol, an indicator of enzyme induction by rifampicin and antiepileptic drugs

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https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

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A double-blind comparison of the efficacy and safety of milnacipran and fluoxetine in depressed inpatients

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

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Genetic polymorphisms of drug metabolizing enzymes

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of venlafaxine on imipramine metabolism

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant drug interactions and the cytochrome P450 system. The role of cytochrome P450 2D6.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

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Pharmacokinetics and drug interactions of antidepressive agents

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of fluvoxamine on the pharmacokinetics of mexiletine in healthy Japanese men.

1 reference

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of adjunctive paroxetine on serum levels and side-effects of tricyclic antidepressants in depressive inpatients

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

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Controlled comparison of two doses of milnacipran (F 2207) and amitriptyline in major depressive inpatients

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of milnacipran in comparison with other antidepressants

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and tolerability of milnacipran: an overview

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Populations and genetic polymorphisms

1 reference

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of CYP2D6, CYP3A4, and other cytochrome P-450 isozymes in N-dealkylation reactions

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between paroxetine and the sparteine oxidation polymorphism

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of recurrent depressive episodes with milnacipran: consequences on quality of life

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paroxetine shifts imipramine metabolism

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The impact of CYP2C19 and CYP2D6 genotypes on metabolism of amitriptyline in Japanese psychiatric patients

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Clinical tolerance of a new antidepressant -- milnacipran].

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical profile of midalcipran (F 2207), 1-phenyl-1-diethyl-aminocarbonyl-2-aminomethyl-cyclopropane (Z) hydrochloride, a potential fourth generation antidepressant drug

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of milnacipran in renal impairment

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of liver metabolic function. Clinical implications

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Milnacipran efficacy in the prevention of recurrent depression: a 12-month placebo-controlled study. Milnacipran recurrence prevention study group

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Which bioequivalence study for a racemic drug? Application to milnacipran

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The decreased in vivo clearance of CYP2D6 substrates by CYP2D6*10 might be caused not only by the low-expression but also by low affinity of CYP2D6.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Death of two subjects due to imipramine and desipramine metabolite accumulation during chronic therapy: a review of the literature and possible mechanisms.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Psychopharmacology of midalcipran, 1-phenyl-1-diethyl-amino-carbonyl-2-aminomethylcyclopropane hydrochloride (F 2207), a new potential antidepressant

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical significance of the sparteine/debrisoquine oxidation polymorphism

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic-pharmacodynamic relationship of the selective serotonin reuptake inhibitors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of imipramine and desipramine

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinically Relevant Pharmacology of Selective Serotonin Reuptake Inhibitors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16122284

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.2165/00003088-200544090-00007

1 reference

stated in

Europe PubMed Central

PubMed publication ID

16122284

retrieved

3 August 2017

Dimensions Publication ID

1053428054

0 references

PubMed publication ID

16122284

1 reference

stated in

Europe PubMed Central

PubMed publication ID

16122284

retrieved

3 August 2017

ResearchGate publication ID

7639022

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