The clinical pharmacokinetics of escitalopram (Q34610822)

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Language	Label	Description	Also known as
English	The clinical pharmacokinetics of escitalopram	scientific article

Statements

instance of

scholarly article

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stated in

Europe PubMed Central

PubMed publication ID

17375980

retrieved

3 August 2017

review article

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stated in

Europe PubMed Central

title

The clinical pharmacokinetics of escitalopram (English)

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Europe PubMed Central

PubMed publication ID

17375980

retrieved

3 August 2017

main subject

escitalopram

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based on heuristic

inferred from title

pharmacokinetics

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based on heuristic

inferred from title

author name string

Niranjan Rao

series ordinal

1

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stated in

Europe PubMed Central

PubMed publication ID

17375980

retrieved

3 August 2017

publication date

1 January 2007

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stated in

Europe PubMed Central

PubMed publication ID

17375980

retrieved

3 August 2017

published in

Clinical Pharmacokinetics

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stated in

Europe PubMed Central

PubMed publication ID

17375980

retrieved

3 August 2017

volume

46

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stated in

Europe PubMed Central

PubMed publication ID

17375980

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3 August 2017

issue

4

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stated in

Europe PubMed Central

PubMed publication ID

17375980

retrieved

3 August 2017

page(s)

281-290

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stated in

Europe PubMed Central

PubMed publication ID

17375980

retrieved

3 August 2017

cites work

Fluvoxamine is a potent inhibitor of cytochrome P4501A2

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug interactions with newer antidepressants: role of human cytochromes P450

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steady-state pharmacokinetics of the enantiomers of citalopram and its metabolites in humans

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetics of escitalopram after oral and intravenous administration of single and multiple doses to healthy subjects

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

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inferred from PubMed ID database lookup

Tricyclic antidepressant plasma levels after augmentation with citalopram: a case study

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

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The emerging role of cytochrome P450 3A in psychopharmacology

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

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inferred from PubMed ID database lookup

Fixed-dose trial of the single isomer SSRI escitalopram in depressed outpatients

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

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Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

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inferred from PubMed ID database lookup

Metabolism of citalopram enantiomers in CYP2C19/CYP2D6 phenotyped panels of healthy Swedes

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

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Carbamazepine augmentation in depressive patients non-responding to citalopram: a pharmacokinetic and clinical pilot study

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The kinetics of citalopram: single and multiple dose studies in man

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Escitalopram in the treatment of generalized anxiety disorder: double-blind, placebo controlled, flexible-dose study

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective serotonin reuptake inhibitors and cytochrome P-450 mediated drug-drug interactions: an update

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

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inferred from PubMed ID database lookup

Non-response to citalopram in depressive patients: pharmacokinetic and clinical consequences of a fluvoxamine augmentation

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacological effect of citalopram residues in the (S)-(+)-enantiomer

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy comparison of escitalopram and citalopram in the treatment of major depressive disorder: pooled analysis of placebo-controlled trials.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-performance liquid chromatographic determination of citalopram and four of its metabolites in plasma and urine samples from psychiatric patients

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic drug interaction potential of selective serotonin reuptake inhibitors.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical significance of the cytochrome P450 2C19 genetic polymorphism

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Citalopram: interaction studies with levomepromazine, imipramine, and lithium

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-Glycoprotein gene disruption

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluvoxamine inhibits the CYP2C19-catalysed metabolism of proguanil in vitro.

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective biotransformation of the selective serotonin reuptake inhibitor citalopram and its demethylated metabolites by monoamine oxidases in human liver

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of multiple dose citalopram on the pharmacokinetics and pharmacodynamics of racemic warfarin.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of P-glycoprotein by newer antidepressants

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of cimetidine or omeprazole on the pharmacokinetics of escitalopram in healthy subjects

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-dose pharmacokinetics of citalopram in patients with moderate renal insufficiency or hepatic cirrhosis compared with healthy subjects.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Escitalopram versus citalopram: the surprising role of the R-enantiomer

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetics of escitalopram in patients with hepatic impairment

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of citalopram on plasma levels of oral theophylline

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of citalopram effect on oral digoxin pharmacokinetics

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transport mechanisms for the antidepressant citalopram in brain microvessel endothelium

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

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Escitalopram : a review of its use in the management of major depressive and anxiety disorders

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Escitalopram (S-enantiomer of citalopram): clinical efficacy and onset of action predicted from a rat model

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of enantiomers of citalopram and its demethylated metabolites in plasma of depressive patients using chiral reverse-phase liquid chromatography

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Second-generation SSRIs: human monoamine transporter binding profile of escitalopram and R-fluoxetine

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Escitalopram in the treatment of panic disorder: a randomized, double-blind, placebo-controlled trial.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of the enantiomers of citalopram, its demethylated and propionic acid metabolites in human plasma by chiral HPLC

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An evaluation of the potential for pharmacokinetic interaction between escitalopram and the cytochrome P450 3A4 inhibitor ritonavir

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of effect of citalopram on the steady-state pharmacokinetics of carbamazepine in healthy male subjects

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A double-blind, placebo-controlled study of citalopram with and without lithium in the treatment of therapy-resistant depressive patients: a clinical, pharmacokinetic, and pharmacogenetic investigation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of CYP2C9 by selective serotonin reuptake inhibitors: in vitro studies with tolbutamide and (S)-warfarin using human liver microsomes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Escitalopram 10 mg/day is effective and well tolerated in a placebo-controlled study in depression in primary care

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

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Escitalopram continuation treatment prevents relapse of depressive episodes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

abcb1ab P-glycoprotein is involved in the uptake of citalopram and trimipramine into the brain of mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro biotransformation of the selective serotonin reuptake inhibitor citalopram, its enantiomers and demethylated metabolites by monoamine oxidase in rat and human brain preparations

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of interaction between citalopram and the CYP3A4 substrate triazolam

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

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Metabolism and excretion of citalopram in man: identification of O-acyl- and N-glucuronides

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

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Escitalopram

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

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Fluoxetine augmentation in citalopram non-responders: pharmacokinetic and clinical consequences

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

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Cytochrome P450 enzymes: interpretation of their interactions with selective serotonin reuptake inhibitors. Part II.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17375980

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.2165/00003088-200746040-00002

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17375980

retrieved

3 August 2017

Dimensions Publication ID

1034172058

0 references

PubMed publication ID

17375980

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17375980

retrieved

3 August 2017

 

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