Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-Glycoprotein gene disruption (Q44612600)

4 December 2017

title

Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-glycoprotein gene disruption (English)

1 reference

4 December 2017

Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-Glycoprotein gene disruption (English)

1 reference

https://api.crossref.org/works/10.1016/S0006-3223(03)00074-X

20 March 2024

Manfred Uhr

1 reference

4 December 2017

Florian Holsboer

1 reference

4 December 2017

Markus T. Grauer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14550684

20 March 2024

language of work or name

English

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publication date

1 October 2003

1 reference

4 December 2017

15 October 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14550684

full work available at URL

20 March 2024

https://api.elsevier.com/content/article/PII:S000632230300074X?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0006-3223(03)00074-X

https://api.elsevier.com/content/article/PII:S000632230300074X?httpAccept=text/plain

20 March 2024

1 reference

https://api.crossref.org/works/10.1016/S0006-3223(03)00074-X

20 March 2024

published in

Biological Psychiatry

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4 December 2017

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4 December 2017

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4 December 2017

page(s)

840-846

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Role of multidrug resistance P-glycoprotein in the secretion of aldosterone by human adrenal NCI-H295 cells

4 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

ATP-dependent transport systems in bacteria and humans: relevance to cystic fibrosis and multidrug resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Genetic analysis of the multidrug transporter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

St Johns wort increases expression of P-glycoprotein: implications for drug interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

ABC Transporters: From Microorganisms to Man

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Penetration of dexamethasone into brain glucocorticoid targets is enhanced in mdr1A P-glycoprotein knockout mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Expression of the mdr (P-glycoprotein) gene in Chinese hamster digestive tracts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Transport mechanisms for the antidepressant citalopram in brain microvessel endothelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Barrier mechanisms in the brain, I. Adult brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Multidrug resistance and the role of P-glycoprotein knockout mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

A general pattern for substrate recognition by P-glycoprotein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Penetration of endogenous steroid hormones corticosterone, cortisol, aldosterone and progesterone into the brain is enhanced in mice deficient for both mdr1a and mdr1b P-glycoproteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

The Functional Role of P-Glycoprotein in the Blood–Brain Barrier

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

In vivo model systems in P-glycoprotein-mediated multidrug resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2803%2900074-X

Pharmacology of drugs that alter multidrug resistance in cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-3223(03)00074-X

20 March 2024

Identifiers

1 reference

4 December 2017

1 reference