Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas (Q34534399)

2 August 2017

title

Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas (English)

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2 August 2017

Bernhard Radlwimmer

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Daniel Mertens

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Peter Lichter

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2 August 2017

Martyna Adamowicz

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2 August 2017

Ralf J Rieker

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2 August 2017

Matthias Schwarzbach

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2 August 2017

Peter Schraml

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2 August 2017

Axel Benner

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2 August 2017

Gunhild Mechtersheimer

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2 August 2017

Stefan Joos

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2 August 2017

publication date

1 September 2006

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Genes, Chromosomes and Cancer

2 August 2017

published in

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

829-838

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Identification of novel neuronal isoforms of the Rho-GEF Trio.

2 August 2017

cites work

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Combined array comparative genomic hybridization and tissue microarray analysis suggest PAK1 at 11q13.5-q14 as a critical oncogene target in ovarian carcinoma

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A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.

21 January 2018

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TRIO amplification and abundant mRNA expression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer

21 January 2018

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Multiple microalterations detected at high frequency in oral cancer

21 January 2018

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High-resolution chromosome arm 5p array CGH analysis of small cell lung carcinoma cell lines

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Chromosomal gains and losses in primary colorectal carcinomas detected by CGH and their associations with tumour DNA ploidy, genotypes and phenotypes

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7 January 2021

The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains

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Amplification of chromosome 5p correlates with increased expression of Skp2 in HPV-immortalized keratinocytes.

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Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

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Chromosome 5p aberrations are early events in lung cancer: implication of glial cell line-derived neurotrophic factor in disease progression

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Iroquois genes: genomic organization and function in vertebrate neural development.

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Mechanisms of sarcoma development

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7 January 2021

New chromosomal regions with high-level amplifications in squamous cell carcinomas of the larynx and pharynx, identified by comparative genomic hybridization

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7 January 2021

Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells

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7 January 2021

Analysis of chromosomal imbalances in sporadic and NF1-associated peripheral nerve sheath tumors by comparative genomic hybridization

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7 January 2021

Skp2 protein expression in soft tissue sarcomas

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7 January 2021

Detection of chromosomal imbalances in leiomyosarcoma by comparative genomic hybridization and interphase cytogenetics

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7 January 2021

When protein destruction runs amok, malignancy is on the loose

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7 January 2021

A new mathematical model for relative quantification in real-time RT-PCR

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7 January 2021

Distinct chromosomal imbalances in pleomorphic and in high-grade dedifferentiated liposarcomas

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7 January 2021

Naked cuticle targets dishevelled to antagonize Wnt signal transduction

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7 January 2021

Cyclooxygenase-2 expression and prostaglandin E(2) synthesis are up-regulated in carcinomas of the cervix: a possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors

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7 January 2021

Elevated telomerase activity,c-MYC-, andhTERTmRNA expression: association with tumour progression in malignant lipomatous tumours

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7 January 2021

Analysis of human telomerase reverse transcriptase mRNA (hTERT) expression in myxoid liposarcomas using LightCycler real-time quantitative reverse transcriptase-polymerase chain reaction

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7 January 2021

Automated array-based genomic profiling in chronic lymphocytic leukemia: development of a clinical tool and discovery of recurrent genomic alterations

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7 January 2021

Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction

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7 January 2021

Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling

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7 January 2021

Co-expression of survivin and TERT and risk of tumour-related death in patients with soft-tissue sarcoma

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7 January 2021

Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd

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7 January 2021

naked cuticle encodes an inducible antagonist of Wnt signalling

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7 January 2021

Detection of chromosomal imbalances in retinoblastoma by matrix-based comparative genomic hybridization

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7 January 2021

Identifiers

DOI

10.1002/GCC.20343

1 reference

2 August 2017

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