Structural mechanisms of costimulation (Q34614732)

3 August 2017

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title

Structural mechanisms of costimulation (English)

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3 August 2017

Steven C Almo

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3 August 2017

author name string

Jean-Claude D Schwartz

series ordinal

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3 August 2017

Xuewu Zhang

series ordinal

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3 August 2017

Stanley G Nathenson

series ordinal

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3 August 2017

language of work or name

English

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publication date

1 May 2002

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3 August 2017

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

427-434

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Protein tyrosine kinase structure and function

3 August 2017

cites work

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https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Erythropoietin receptor activation by a ligand-induced conformation change

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7 January 2021

Quaternary structure of the insulin-insulin receptor complex

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7 January 2021

Structural basis for co-stimulation by the human CTLA-4/B7-2 complex

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7 January 2021

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses

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7 January 2021

The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity

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7 January 2021

Crystal structure of an Eph receptor-ephrin complex

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7 January 2021

CD28/B7 system of T cell costimulation

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7 January 2021

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

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7 January 2021

Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

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7 January 2021

Functional responses and costimulator dependence of memory CD4+ T cells.

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha

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https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

T-cell co-stimulation through B7RP-1 and ICOS

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https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

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https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells

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https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

The immunological synapse.

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https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

T cell receptor signaling precedes immunological synapse formation

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https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Immunology. The immunological synapse--a multitasking system

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7 January 2021

CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy

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7 January 2021

Cloning of B7-2: a CTLA-4 Counter-Receptor That Costimulates Human T Cell Proliferation

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https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Structure and dimerization of a soluble form of B7-1

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7 January 2021

Expression, refolding, purification, molecular characterization, crystallization, and preliminary X-ray analysis of the receptor binding domain of human B7-2.

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7 January 2021

Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28

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7 January 2021

The immunoglobulin superfamily--domains for cell surface recognition

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https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Structure of murine CTLA-4 and its role in modulating T cell responsiveness

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Immunoglobulin fold characteristics of B7-1 (CD80) and B7-2 (CD86).

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 A resolution

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

1 reference

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7 January 2021

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1.

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Transmembrane signaling through CD80 (B7-1) induces growth arrest and cell spreading of human B lymphocytes accompanied by protein tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells

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https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Distinct role of CD80 and CD86 in the regulation of the activation of B cell and B cell lymphoma

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https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Structural basis of cell-cell adhesion by cadherins

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

The immunological synapse and CD28-CD80 interactions.

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Dependence of T cell antigen recognition on the dimensions of an accessory receptor-ligand complex

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Developmentally regulated glycosylation of the CD8alphabeta coreceptor stalk modulates ligand binding

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

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https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Crystal Structure at 1.7 Å Resolution of VEGF in Complex with Domain 2 of the Flt-1 Receptor

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7 January 2021

Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

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7 January 2021

Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Physiological regulation of the immunological synapse by agrin

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Tumor necrosis factor receptor and Fas signaling mechanisms.

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Identification and characterization of a ligand-independent oligomerization domain in the extracellular region of the CD95 death receptor

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Signalling through the high-affinity IgE receptor Fc epsilonRI.

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Dali: a network tool for protein structure comparison

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

[25] Protein multiple sequence alignment and flexible pattern matching

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Molecular basis of T cell inactivation by CTLA-4

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein

1 reference

https://api.crossref.org/works/10.1038%2FNI0502-427

7 January 2021

Identifiers

DOI

10.1038/NI0502-427

1 reference

3 August 2017

1 reference