Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation (Q24675931)

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Y Iwai

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K Bourque

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T Chernova

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H Nishimura

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L J Fitz

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N Malenkovich

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T Okazaki

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M C Byrne

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H F Horton

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L Fouser

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L Carter

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V Ling

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M R Bowman

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B M Carreno

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M Collins

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C R Wood

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T Honjo

Journal of Experimental Medicine

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language of work or name

English

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publication date

2 October 2000

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published in

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volume

192

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issue

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page(s)

1027-34

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cites work

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Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

7 April 2017

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Cutting edge: identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor

7 April 2017

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7 April 2017

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Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

7 April 2017

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7 April 2017

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The costimulatory genes Cd80 and Cd86 are linked on mouse chromosome 16 and human chromosome 3

7 April 2017

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Characterization of murine Flt4 ligand/VEGF-C

7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

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B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha

7 April 2017

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Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses

28 September 2017

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The BB1 monoclonal antibody recognizes both cell surface CD74 (MHC class II-associated invariant chain) as well as B7-1 (CD80), resolving the question regarding a third CD28/CTLA-4 counterreceptor

28 September 2017

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Discordant expression of CD28 ligands, BB-1, and B7 on keratinocytes in vitro and psoriatic cells in vivo.

28 September 2017

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CTLA-4 and CD28 mRNA are coexpressed in most T cells after activation. Expression of CTLA-4 and CD28 mRNA does not correlate with the pattern of lymphokine production

28 September 2017

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28 September 2017

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The complexities of T-cell co-stimulation: CD28 and beyond

28 September 2017

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The role of B7-1/B7-2:CD28/CLTA-4 pathways in the prevention of anergy, induction of productive immunity and down-regulation of the immune response

28 September 2017

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The emerging role of CTLA-4 as an immune attenuator

28 September 2017

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CTLA-4 ligation delivers a unique signal to resting human CD4 T cells that inhibits interleukin-2 secretion but allows Bcl-X(L) induction

30 May 2018

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Selective induction of B7/BB-1 on interferon-γ stimulated monocytes: A potential mechanism for amplification of T cell activation through the CD28 pathway

28 November 2018

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