The E-cadherin cell-cell adhesion complex and lung cancer invasion, metastasis, and prognosis (Q34602723)

3 August 2017

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title

The E-cadherin cell-cell adhesion complex and lung cancer invasion, metastasis, and prognosis (English)

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3 August 2017

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Fred R Hirsch

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3 August 2017

Roy M Bremnes

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3 August 2017

Robert Veve

series ordinal

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3 August 2017

Wilbur A Franklin

series ordinal

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3 August 2017

publication date

1 May 2002

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3 August 2017

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

115-124

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3 August 2017

cites work

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Reduced E-cadherin expression is associated with increased lymph node metastasis and unfavorable prognosis in non-small cell lung cancer

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Reduced expression of plakoglobin indicates an unfavorable prognosis in subsets of patients with non-small-cell lung cancer

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7 January 2021

Cadherin and catenin expression in normal human bronchial epithelium and non-small cell lung cancer

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Prognostic value of nucleolar protein p120 in patients with resected lung adenocarcinoma

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7 January 2021

The role of E-cadherin expression in non-small cell lung cancer

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7 January 2021

Reduced expression of alpha-catenin, beta-catenin, and gamma-catenin is associated with high cell proliferative activity and poor differentiation in non-small cell lung cancer

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7 January 2021

E-cadherin expression associated with differentiation and prognosis in patients with non-small cell lung cancer

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Cadherins and catenins in development

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7 January 2021

Adhesion molecules as determinants of disease: from molecular biology to surgical research

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7 January 2021

Changes in gene structure and regulation of E-cadherin during epithelial development, differentiation, and disease

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7 January 2021

E-cadherin-catenin cell-cell adhesion complex and human cancer

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7 January 2021

E-cadherin mediated adhesion system in cancer cells

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7 January 2021

Structural basis of cell-cell adhesion by cadherins

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7 January 2021

The uvomorulin-anchorage protein alpha catenin is a vinculin homologue

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7 January 2021

A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin

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7 January 2021

Plakoglobin, or an 83-kD homologue distinct from beta-catenin, interacts with E-cadherin and N-cadherin

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7 January 2021

Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes

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7 January 2021

E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells

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7 January 2021

Loss of E-cadherin-dependent cell-cell adhesion due to mutation of the beta-catenin gene in a human cancer cell line, HSC-39

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7 January 2021

Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA

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7 January 2021

Cell-cell contacts mediated by E-cadherin (uvomorulin) restrict invasive behavior of L-cells

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7 January 2021

Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion

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7 January 2021

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

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7 January 2021

A role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis

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7 January 2021

Decreased expression of E-cadherin and increased invasive capacity in EBV-LMP-transfected human epithelial and murine adenocarcinoma cells

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7 January 2021

Reduced E-cadherin expression correlates with increased invasiveness in colorectal carcinoma cell lines

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7 January 2021

Deletion of the E-cadherin gene in hepatitis B virus-positive Chinese hepatocellular carcinomas

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7 January 2021

Genetic and biochemical dissection of protein linkages in the cadherin-catenin complex

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7 January 2021

Poorly differentiated colon carcinoma cell lines deficient in alpha-catenin expression express high levels of surface E-cadherin but lack Ca(2+)-dependent cell-cell adhesion

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7 January 2021

A short core region of E-cadherin is essential for catenin binding and is highly phosphorylated

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7 January 2021

Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor

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7 January 2021

Effect of epidermal growth factor on cadherin-mediated adhesion in a human oesophageal cancer cell line

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7 January 2021

Overexpression of ERBB2 in human mammary epithelial cells signals inhibition of transcription of the E-cadherin gene

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7 January 2021

Cadherin and catenin biology represent a global mechanism for epithelial cancer progression

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7 January 2021

How a growth control path takes a wrong turn to cancer

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7 January 2021

Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes

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7 January 2021

Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin

1 reference

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7 January 2021

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

1 reference

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7 January 2021

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

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7 January 2021

Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability

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7 January 2021

Functional interaction of beta-catenin with the transcription factor LEF-1

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7 January 2021

TCF/LEF factors earn their wings

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7 January 2021

Nuclear endpoint of Wnt signaling: neoplastic transformation induced by transactivating lymphoid-enhancing factor 1.

1 reference

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7 January 2021

Identification of c-MYC as a target of the APC pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro

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7 January 2021

Uncoupling cadherin-based adhesion from wingless signalling in Drosophila.

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7 January 2021

Molecular organization of the uvomorulin-catenin complex

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7 January 2021

Binding to cadherins antagonizes the signaling activity of beta-catenin during axis formation in Xenopus

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7 January 2021

A mode of regulation of beta-catenin signaling activity in Xenopus embryos independent of its levels

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7 January 2021

Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover

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7 January 2021

The APC tumour suppressor has a nuclear export function.

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7 January 2021

CRM1- and Ran-independent nuclear export of beta-catenin.

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https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

E-Cadherin-dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27(KIP1)

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https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

p27 is involved in N-cadherin-mediated contact inhibition of cell growth and S-phase entry

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7 January 2021

Unstable expression of E-cadherin adhesion molecules in metastatic ovarian tumor cells

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7 January 2021

Down-regulation of E-cadherin expression in Madin Darby canine kidney (MDCK) cells inside tumors of nude mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Changes in E-cadherin immunoreactivity in the adenoma-carcinoma sequence of the large bowel

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

A causal role for E-cadherin in the transition from adenoma to carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Morphoregulatory activities of E-cadherin and beta-1 integrins in colorectal tumour cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

The E-cadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Soluble E-cadherin fragments increased in circulation of cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Regional assignment of the human loci for uvomorulin (UVO) and chymotrypsinogen B (CTRB) with the help of two overlapping deletions on the long arm of chromosome 16

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

The 102 kd cadherin-associated protein: similarity to vinculin and posttranscriptional regulation of expression

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Identification of a neural α-catenin as a key regulator of cadherin function and multicellular organization

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

p120(ctn) acts as an inhibitory regulator of cadherin function in colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Changes in E-cadherin associated with cytoplasmic molecules in well and poorly differentiated endometrial cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Decreased E-cadherin expression is associated with haematogenous recurrence and poor prognosis in patients with squamous cell carcinoma of the oesophagus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Loss of p120ctn in human colorectal cancer predicts metastasis and poor survival

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Reduced E-cadherin immunohistochemical expression in node-negative breast carcinomas correlates with 10-year survival

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Reduced expression of the cadherin-catenin complex in oesophageal adenocarcinoma correlates with poor prognosis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Prognostic significance of E-cadherin/catenin complex expression in gastric cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Prognostic value of the preserved expression of the E-cadherin and catenin families of adhesion molecules and of beta-catenin mutations in synovial sarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

The prognostic significance of proliferation-associated nucleolar protein p120 expression in prostate adenocarcinoma: a comparison with cyclins A and B1, Ki-67, proliferating cell nuclear antigen, and p34cdc2.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Nuclear localization of beta-catenin is an important prognostic factor in hepatoblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Prognostic significance of histologic grade and nuclear expression of beta-catenin in synovial sarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Nuclear beta catenin expression is related to unfavourable outcome in oropharyngeal and hypopharyngeal squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

A comparative study of the clinicopathological significance of E-cadherin and catenins (α, β, γ) expression in the surgical management of oral tongue carcinoma

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https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Differences of E-cadherin expression levels and patterns in human lung cancer

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https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Cytoplasmic redistribution of E-cadherin-catenin adhesion complex is associated with down-regulated tyrosine phosphorylation of E-cadherin in human bronchopulmonary carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Frequent loss of alpha catenin expression in scirrhous carcinomas with scattered cell growth.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Immunohistochemical evaluation of E-cadherin adhesion molecule expression in human gastric cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Loss of membranous E-cadherin expression in pancreatic cancer: correlation with lymph node metastasis, high grade, and advanced stage

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

E-cadherin and alpha-, beta-, and gamma-catenin protein expression in relation to metastasis in human breast carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Prognostic value of E-cadherin expression in 413 gastric carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Lung cancer chemoprevention

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Activation of the E-cadherin/catenin complex in human MCF-7 breast cancer cells by all-trans-retinoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Progestins and danazol effect on cell-to-cell adhesion, and E-cadherin and alpha- and beta-catenin mRNA expressions

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Antiproliferative activity of interferon alpha and retinoic acid in SiHa carcinoma cells: the role of cell adhesion.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Novel progesterone target genes identified by an improved differential display technique suggest that progestin-induced growth inhibition of breast cancer cells coincides with enhancement of differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

All‐trans‐retinoic Acid‐dependent Inhibition of E‐Cadherin‐based Cell Adhesion with Concomitant Dephosphorylation of β‐Catenin in Metastatic Human Renal Carcinoma Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Aspirin prevents tumors in a murine model of familial adenomatous polyposis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Insulin-like growth factor I activates the invasion suppressor function of E-cadherin in MCF-7 human mammary carcinoma cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-5002%2801%2900471-8

7 January 2021

10.1016/S0169-5002(01)00471-8

Identifiers

DOI

1 reference

3 August 2017

1 reference