Epidermal growth factor receptor defects in leprechaunism. A multiple growth factor-resistant syndrome (Q34579285)

3 August 2017

title

Epidermal growth factor receptor defects in leprechaunism. A multiple growth factor-resistant syndrome (English)

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3 August 2017

C R Kahn

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3 August 2017

S S Reddy

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3 August 2017

language of work or name

English

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publication date

1 November 1989

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Journal of Clinical Investigation

3 August 2017

published in

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

1569-1576

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Stimulation of glucose incorporation and amino acid transport by insulin and an insulin-like growth factor in fibroblasts with defective insulin receptors cultured from a patient with leprechaunism

3 August 2017

cites work

1 reference

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Fibroblasts from a Patient with Leprechaunism Are Resistant to Insulin, Epidermal Growth Factor, and Somatomedin C*

7 July 2018

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Receptors for insulinlike growth factor I are defective in fibroblasts cultured from a patient with leprechaunism

7 July 2018

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Effects of Epidermal Growth Factor and 12-O-Tetradecanoylphorbol-13-Acetate on Metabolism of the Epidermal Growth Factor Receptor in Normal Human Fibroblasts

7 July 2018

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Mechanisms of insulin resistance in cultured fibroblasts from a patient with leprechaunism: impaired post-binding actions of insulin and multiplication-stimulating activity.

7 July 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

7 July 2018

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Phenotypic expression in Donohue syndrome (leprechaunism): a role for epidermal growth factor

7 July 2018

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Decreased levels of hepatic epidermal growth factor receptors in obese hyperglycemic rodents

7 July 2018

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7 July 2018

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Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity

7 July 2018

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Characterization of binding and phosphorylation defects of erythrocyte insulin receptors in the type A syndrome of insulin resistance

7 July 2018

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Decreased binding of epidermal growth factor in placentas from streptozotocin-diabetic rats

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Diacylglycerol treatment rapidly decreases the affinity of the epidermal growth factor receptors of Swiss 3T3 cells

7 July 2018

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Two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance.

7 July 2018

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An insertional mutant of epidermal growth factor receptor allows dissection of diverse receptor functions

7 July 2018

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The EGF receptor: structure, regulation and potential role in malignancy

7 July 2018

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7 July 2018

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Primary defect of insulin receptors in skin fibroblasts cultured from an infant with leprechaunism and insulin resistance

7 July 2018

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7 July 2018

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Inhibition by bacitracin of rat adipocyte plasma membrane degradation of 125I-insulin is associated with an increase in plasma membrane bound insulin and a potentiation of glucose oxidation by adipocytes.

27 October 2018

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Autophosphorylation and protein kinase C phosphorylation of the epidermal growth factor receptor. Effect on tyrosine kinase activity and ligand binding affinity

27 October 2018

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Two alternative mechanisms control the interconversion of functional states of the epidermal growth factor receptor

27 October 2018

1 reference

12 December 2020

Leprechaunism: a euphemism for a rare familial disorder

1 reference

12 December 2020

Decreased insulin binding in cultured lymphocytes from two patients with extreme insulin resistance

1 reference

12 December 2020

Insulin binding and insulin-dependent phosphorylation of the insulin receptor solubilized from human erythrocytes

1 reference

12 December 2020

Reconstitution of human epidermal growth factor receptors and its deletion mutants in cultured hamster cells

1 reference

12 December 2020

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets

1 reference

12 December 2020

Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases

1 reference

12 December 2020

Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst

1 reference

12 December 2020

Defects in insulin binding and autophosphorylation of erythrocyte insulin receptors in patients with syndromes of severe insulin resistance and their parents

1 reference

12 December 2020

Mechanism of protein kinase C inhibition by sphingosine

1 reference

12 December 2020

Nonselective inhibition of neutrophil functions by sphinganine

1 reference

12 December 2020

Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI114334

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3 August 2017

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3 August 2017

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