Apaf-1 is a transcriptional target for E2F and p53 (Q57274134)

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English	Apaf-1 is a transcriptional target for E2F and p53	No description defined

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instance of

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title

Apaf-1 is a transcriptional target for E2F and p53 (English)

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author

Francesco Cecconi

object named as

Francesco Cecconi

series ordinal

6

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Kristian Helin

object named as

Kristian Helin

series ordinal

8

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author name string

M. Cristina Moroni

series ordinal

1

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Emma S. Hickman

series ordinal

2

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Eros Lazzerini Denchi

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3

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Greta Caprara

series ordinal

4

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Elena Colli

series ordinal

5

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Heiko Müller

series ordinal

7

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publication date

June 2001

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published in

Nature Cell Biology

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volume

3

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issue

6

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page(s)

552-558

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cites work

Cancer cell cycles

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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The Hallmarks of Cancer

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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The retinoblastoma gene family in differentiation and development.

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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The regulation of E2F by pRB-family proteins

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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p53 and E2F-1 cooperate to mediate apoptosis

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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E2F-1-induced p53-independent apoptosis in transgenic mice.

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

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7 January 2021

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Role for the p53 homologue p73 in E2F-1-induced apoptosis

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

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7 January 2021

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p14ARF links the tumour suppressors RB and p53.

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Tumor surveillance via the ARF-p53 pathway.

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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p73 is a simian [correction of human] p53-related protein that can induce apoptosis

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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The biochemistry of apoptosis

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Apaf1 is required for mitochondrial pathways of apoptosis and brain development

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Caspase-9 and APAF-1 form an active holoenzyme

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L).

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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A matter of life and cell death

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

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Crossref

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Regulation of the cyclin E gene by transcription factor E2F1

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Oncogene-dependent apoptosis is mediated by caspase-9.

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https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

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Crossref

reference URL

https://api.crossref.org/works/10.1038%2F35078527

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7 January 2021

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Identifiers

DOI

10.1038/35078527

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PubMed publication ID

11389439

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