p38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines. (Q34483284)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

review article

1 reference

title

p38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

0 references

J L Adams

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

A M Badger

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

S Kumar

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

J C Lee

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

publication date

1 January 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json

Progress in medicinal chemistry

5 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

page(s)

1-60

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json

Consideration of cytokines as therapeutics agents or targets

5 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Therapeutic potential and strategies for inhibiting tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Cytokine blockade as a new strategy to treat rheumatoid arthritis: inhibition of tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

The role of cytokines in rheumatoid arthritis: inhibition of cytokines in therapeutic trials

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Inhibition of monocyte IL-1 production by the anti-inflammatory compound, SK&F 86002

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Effect of SK&F 86002 on cytokine production by human monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Pyridinyl imidazoles inhibit IL-1 and TNF production at the protein level

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

1 reference

7 January 2021

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Interleukin 1 alpha activates two forms of p54 alpha mitogen-activated protein kinase in rabbit liver

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Localization of the human stress responsive MAP kinase-like CSAIDs binding protein (CSBP) gene to chromosome 6q21.3/21.2.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

p38-2, a novel mitogen-activated protein kinase with distinct properties.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

The primary structure of p38 gamma: a new member of p38 group of MAP kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Activation of the novel MAP kinase homologue SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6).

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Murine p38-delta mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Activation of the MAP kinase homologue RK requires the phosphorylation of Thr-180 and Tyr-182 and both residues are phosphorylated in chemically stressed KB cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Identification of MAP kinase domains by redirecting stress signals into growth factor responses

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Structure-function studies of p38 mitogen-activated protein kinase. Loop 12 influences substrate specificity and autophosphorylation, but not upstream kinase selection

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Molecular determinants that mediate selective activation of p38 MAP kinase isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

MEK kinase 3 directly activates MKK6 and MKK7, specific activators of the p38 and c-Jun NH2-terminal kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Protein modification: docking sites for kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Identification of two distinct regions of p38 MAPK required for substrate binding and phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

3pK, a new mitogen-activated protein kinase-activated protein kinase located in the small cell lung cancer tumor suppressor gene region

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

MAPKAPK5, a novel mitogen-activated protein kinase (MAPK)-activated protein kinase, is a substrate of the extracellular-regulated kinase (ERK) and p38 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Modulation of actin dynamics during stress and physiological stimulation by a signaling pathway involving p38 MAP kinase and heat-shock protein 27.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

MAPKAP kinase 2 phosphorylates serum response factor in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

PRAK, a novel protein kinase regulated by the p38 MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

p38 Mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Regulation of the MEF2 family of transcription factors by p38

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Convergence of MAP kinase pathways on the ternary complex factor Sap-1a

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Kinetic mechanism for p38 MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Kinetic mechanism of the p38-alpha MAP kinase: phosphoryl transfer to synthetic peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Cytosolic Phospholipase A2 Is Phosphorylated in Collagen- and Thrombin-stimulated Human Platelets Independent of Protein Kinase C and Mitogen-activated Protein Kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

The activation state of p38 mitogen-activated protein kinase determines the efficiency of ATP competition for pyridinylimidazole inhibitor binding

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

5,6-Diaryl-2,3-dihydroimidazo[2,1-b]thiazoles: a new class of immunoregulatory antiinflammatory agents

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Antiinflammatory activity of 5,6-diaryl-2,3-dihydroimidazo[2,1-b]thiazoles. Isomeric 4-pyridyl and 4-substituted phenyl derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

SK&F 86002: a structurally novel anti-inflammatory agent that inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Ovarian effects of SK&F 86002-A2 in the rat: site of action.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Comparative biochemical and morphometric changes associated with induction of the hepatic mixed function oxidase system in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Pharmacology of the pyrroloimidazole, SK&F 105809--I. Inhibition of inflammatory cytokine production and of 5-lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Pyrimidinylimidazole inhibitors of CSBP/p38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Pyrroles and other heterocycles as inhibitors of p38 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Comparison of suppressive effects of a new anti-inflammatory compound, FR167653, on production of PGE2 and inflammatory cytokines, human monocytes, and alveolar macrophages in response to endotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Effect of FR167653, a cytokine suppressive agent, on endotoxin-induced disseminated intravascular coagulation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Paradoxical activation of Raf by a novel Raf inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

p38 mitogen-activated protein kinase inhibitors--mechanisms and therapeutic potentials

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

The structure of mitogen-activated protein kinase p38 at 2.1-A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Crystal structure of p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Structural basis of inhibitor selectivity in MAP kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Nonopsonic binding of type III Group B Streptococci to human neutrophils induces interleukin-8 release mediated by the p38 mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

PAF-induced RANTES production by human airway smooth muscle cells requires both p38 MAP kinase and Erk

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

RAC1/P38 MAPK signaling pathway controls beta1 integrin-induced interleukin-8 production in human natural killer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Interleukin 1 (IL1) and tumour necrosis factor (TNF) signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Role for p38 mitogen-activated protein kinase in platelet aggregation caused by collagen or a thromboxane analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Selective activation of JNK/SAPK by interleukin-1 in rabbit liver is mediated by MKK7

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Inhibition of tumor necrosis factor mRNA translation by a rationally designed immunomodulatory peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Regulation of transcription by MAP kinase cascades

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Fas induces cytoplasmic apoptotic responses and activation of the MKK7-JNK/SAPK and MKK6-p38 pathways independent of CPP32-like proteases.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Apoptosis signaling pathway in T cells is composed of ICE/Ced-3 family proteases and MAP kinase kinase 6b

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Regulation of Rb and E2F by signal transduction cascades: divergent effects of JNK1 and p38 kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Tumor necrosis factor-alpha mediates antiapoptotic signals partially via p38 MAP kinase activation in human eosinophils

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Inhibition of p38 mitogen-activated protein kinase by insulin in cultured fetal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Inhibitors of p38 mitogen-activated protein kinase promote neuronal survival in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Rapid and long-lasting suppression of the ATF-2 transcription factor is a common response to neuronal injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Apoptosis of cerebellar granule cells induced by serum withdrawal, glutamate or beta-amyloid, is independent of Jun kinase or p38 mitogen activated protein kinase activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

An inhibitor of p38 and JNK MAP kinases prevents activation of caspase and apoptosis of cultured cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

p38 kinase is activated in the Alzheimer's disease brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCaT cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Induction of apoptosis signal regulating kinase 1 (ASK1) after spinal cord injury in rats: possible involvement of ASK1-JNK and -p38 pathways in neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

SB203580 reverses adrenomedullin's effect on proliferation and apoptosis in cultured mesangial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Activation of the p38 mitogen-activated protein kinase pathway by estrogen or by 4-hydroxytamoxifen is coupled to estrogen receptor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

p38 MAP kinase regulates TNF alpha-, IL-1 alpha- and PAF-induced RANTES and GM-CSF production by human bronchial epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

p38 mitogen-activated protein kinase inhibition attenuates intercellular adhesion molecule-1 up-regulation on human pulmonary microvascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Models and mechanisms of exercise-induced asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Hyperosmolarity-induced interleukin-8 expression in human bronchial epithelial cells through p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Oxidants and antioxidants as therapeutic targets in chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Hypoxic Stimulation of the Stress-activated Protein Kinases in Pulmonary Artery Fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

MAP kinases, phosphatidylinositol 3-kinase, and p70 S6 kinase mediate the mitogenic response of human endothelial cells to vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

p38 mitogen-activated protein kinase activation is required for fibroblast growth factor-2-stimulated cell proliferation but not differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the signal transduction of basic fibroblast growth factor in endothelial cells during angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

A Role for p38MAPK/HSP27 Pathway in Smooth Muscle Cell Migration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Activation of the HIV-1 long terminal repeat by cytokines and environmental stress requires an active CSBP/p38 MAP kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Activation of NF-kappa B and p38 MAP kinase is not sufficient for triggering efficient HIV gene expression in response to stress

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

The critical role of p38 MAP kinase in T cell HIV-1 replication.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Role of p38 mitogen-activated protein kinase in HIV type 1 production in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

p38 mitogen-activated protein kinase and c-jun-NH2-terminal kinase regulate RANTES production by influenza virus-infected human bronchial epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Role of p38 mitogen-activated protein kinase in rhinovirus-induced cytokine production by bronchial epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Activation of the mitogen-activated protein kinase p38 by human cytomegalovirus infection through two distinct pathways: a novel mechanism for activation of p38.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Epstein-Barr virus immediate-early proteins BZLF1 and BRLF1 activate the ATF2 transcription factor by increasing the levels of phosphorylated p38 and c-Jun N-terminal kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Activation of p38 mitogen-activated protein kinase and c-Jun NH(2)-terminal kinase by double-stranded RNA and encephalomyocarditis virus: involvement of RNase L, protein kinase R, and alternative pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Herpes simplex virus type 1 infection stimulates p38/c-Jun N-terminal mitogen-activated protein kinase pathways and activates transcription factor AP-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Acute infection of Sindbis virus induces phosphorylation and intracellular translocation of small heat shock protein HSP27 and activation of p38 MAP kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Activation of ERK2 by respiratory syncytial virus in A549 cells is linked to the production of interleukin 8.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Cytokine suppressive anti-inflammatory compounds inhibit bone resorption in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Selective activation of the mitogen-activated protein kinase subgroups c-Jun NH2 terminal kinase and p38 by IL-1 and TNF in human articular chondrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Immortalized human adult articular chondrocytes maintain cartilage-specific phenotype and responses to interleukin-1beta

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Regulation of nitric oxide and prostaglandin E2 production by CSAIDS (SB203580) in murine macrophages and bovine chondrocytes stimulated with LPS.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Role of MAP kinase cascades in inducing arginine transporters and nitric oxide synthetase in RAW264 macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

The role of p38 mitogen-activated protein kinase in IL-6 and IL-8 production from the TNF-alpha- or IL-1beta-stimulated rheumatoid synovial fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Induction of collagenase-3 (MMP-13) expression in human skin fibroblasts by three-dimensional collagen is mediated by p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Pharmacologic characterization of the antiinflammatory properties of a new dual inhibitor of lipoxygenase and cyclooxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

6-Amino-2-(4-fluorophenyl)-4-methoxy-3- (4-pyridyl)-1H-pyrrolo[2, 3-b]pyridine (RWJ 68354): a potent and selective p38 kinase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Effect of inhibitors of eicosanoid metabolism in murine collagen-induced arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Inflammatory mediators and stroke: new opportunities for novel therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Role of p38 MAP kinase in myocardial stress

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

A p38 MAP kinase inhibitor SB203580 inhibits CD28-dependent T cell proliferation and IL-2 production

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Pyridinyl imidazoles inhibit the inflammatory phase of delayed type hypersensitivity reactions without affecting T-dependent immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

The pyridinyl imidazole inhibitor SB203580 blocks phosphoinositide-dependent protein kinase activity, protein kinase B phosphorylation, and retinoblastoma hyperphosphorylation in interleukin-2-stimulated T cells independently of p38 mitogen-activate

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Raf-1 is activated by the p38 mitogen-activated protein kinase inhibitor, SB203580.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Potent inhibitors of the MAP kinase p38

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Inhibition of MAP kinase kinase (MEK) results in an anti-inflammatory response in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Bicyclic imidazoles as a novel class of cytokine biosynthesis inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

Transforming growth factor-beta induces collagenase-3 expression by human gingival fibroblasts via p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2

7 January 2021

10.1016/S0079-6468(08)70091-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json