MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis (Q28593865)

31 January 2017

title

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis (English)

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MAP kinase-activated protein kinase 2

31 January 2017

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GOA release 2020-03-11

M. Gaestel

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31 January 2017

A. Kotlyarov

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31 January 2017

A. Neininger

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31 January 2017

C. Schubert

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31 January 2017

R. Eckert

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31 January 2017

C. Birchmeier

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31 January 2017

H. D. Volk

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31 January 2017

publication date

1 June 1999

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31 January 2017

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31 January 2017

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31 January 2017

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31 January 2017

page(s)

94–97

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A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

31 January 2017

cites work

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7 January 2021

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

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7 January 2021

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

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7 January 2021

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

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7 January 2021

The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways

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7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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Activation of the protein kinase p38 in the spindle assembly checkpoint and mitotic arrest.

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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Bicyclic imidazoles as a novel class of cytokine biosynthesis inhibitors

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The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes

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3pK, a new mitogen-activated protein kinase-activated protein kinase located in the small cell lung cancer tumor suppressor gene region

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7 January 2021

MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

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7 January 2021

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

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7 January 2021

PRAK, a novel protein kinase regulated by the p38 MAP kinase

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7 January 2021

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

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7 January 2021

Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

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7 January 2021

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

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7 January 2021

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

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7 January 2021

Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins

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7 January 2021

Galactosamine-induced sensitization to the lethal effects of endotoxin

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Lipopolysaccharide-binding protein is required to combat a murine Gram-negative bacterial infection

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Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

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Characterization of tumor necrosis factor-deficient mice

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7 January 2021

Role of lymphotoxin and the type I TNF receptor in the formation of germinal centers

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Monensin inhibits initial spreading of cultured human fibroblasts

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7 January 2021

Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation

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7 January 2021

Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2

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7 January 2021

PMA-induced activation of the p42/44ERK- and p38RK-MAP kinase cascades in HL-60 cells is PKC dependent but not essential for differentiation to the macrophage-like phenotype

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7 January 2021

Functional and molecular characterization of single, (4-hydroxy-3-nitrophenyl)acetyl (NP)-specific, IgG1+ B cells from antibody-secreting and memory B cell pathways in the C57BL/6 immune response to NP.

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7 January 2021