Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6. (Q34484412)

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14 January 2020

title

Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6 (English)

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14 January 2020

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14 January 2020

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14 January 2020

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14 January 2020

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14 January 2020

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14 January 2020

Alois Kozubík

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14 January 2020

Igor Červenka

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14 January 2020

Joshua Wolf

series ordinal

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14 January 2020

William R Wilcox

series ordinal

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14 January 2020

language of work or name

English

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publication date

25 October 2010

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Molecular and Cellular Biology

14 January 2020

published in

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14 January 2020

volume

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issue

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14 January 2020

page(s)

179-189

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Cell cycle control of wnt receptor activation

14 January 2020

cites work

1 reference

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EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin.

6 July 2018

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G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.

6 July 2018

1 reference

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Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6.

6 July 2018

1 reference

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Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling

6 July 2018

1 reference

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p38 mitogen-activated protein kinase regulates canonical Wnt-beta-catenin signaling by inactivation of GSK3beta

6 July 2018

1 reference

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Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development

6 July 2018

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LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin

6 July 2018

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Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation.

6 July 2018

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Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6.

6 July 2018

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G alpha o mediates WNT-JNK signaling through dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells

6 July 2018

1 reference

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Multiple PPPS/TP motifs act in a combinatorial fashion to transduce Wnt signaling through LRP6.

6 July 2018

1 reference

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Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

6 July 2018

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Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation

6 July 2018

1 reference

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Wnt/beta-catenin signaling in development and disease

6 July 2018

1 reference

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Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin

6 July 2018

1 reference

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Cross-talk of WNT and FGF signaling pathways at GSK3beta to regulate beta-catenin and SNAIL signaling cascades

6 July 2018

1 reference

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Balancing cell adhesion and Wnt signaling, the key role of beta-catenin

6 July 2018

1 reference

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A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

6 July 2018

1 reference

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Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction

6 July 2018

1 reference

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Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions

6 July 2018

1 reference

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FGF2 inhibits proliferation and alters the cartilage-like phenotype of RCS cells

6 July 2018

1 reference

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A mechanism for Wnt coreceptor activation

6 July 2018

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A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor

6 July 2018

1 reference

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FGF-1 and FGF-2 modulate the E-cadherin/catenin system in pancreatic adenocarcinoma cell lines

6 July 2018

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6 July 2018

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Characterization of mouse dishevelled (Dvl) proteins in Wnt/Wingless signaling pathway

6 July 2018

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MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade

6 July 2018

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Wnt and FGF pathways cooperatively pattern anteroposterior neural ectoderm in Xenopus.

6 July 2018

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The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2

6 July 2018

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Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification

6 July 2018

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The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

6 July 2018

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A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function

6 July 2018

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Increased apoptosis in differentiating p27-deficient mouse embryonic stem cells.

6 July 2018

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Casein kinase I transduces Wnt signals

27 October 2018

1 reference

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Serine Phosphorylation-regulated Ubiquitination and Degradation of β-Catenin

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20974802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.00550-10

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14 January 2020

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14 January 2020

PubMed publication ID

20974802

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json