Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling (Q24310506)

LDL receptor related protein 6

1 reference

negative regulation of protein serine/threonine kinase activity

1 reference

Axin 1

1 reference

Glycogen synthase kinase 3 beta

1 reference

Catenin (cadherin associated protein), beta 1

1 reference

William I Weis

William I

Weis

1 reference

19 October 2023

Jaewon Lee

Jaewon

Lee

1 reference

19 October 2023

Shunfu Piao

Shunfu

Piao

1 reference

19 October 2023

Sun-Hye Lee

Sun-Hye

Lee

1 reference

19 October 2023

Hyunjoon Kim

Hyunjoon

Kim

1 reference

19 October 2023

Soohwan Yum

Soohwan

Yum

1 reference

19 October 2023

Jennifer L Stamos

Jennifer L

Stamos

1 reference

19 October 2023

Yongbin Xu

Yongbin

1 reference

19 October 2023

Su-Jin Lee

Su-Jin

Lee

1 reference

19 October 2023

Sangtaek Oh

Sangtaek

1 reference

19 October 2023

Jin-Kwan Han

Jin-Kwan

Han

1 reference

19 October 2023

Bum-Joon Park

Bum-Joon

Park

1 reference

19 October 2023

Nam-Chul Ha

Nam-Chul

1 reference

Creative Commons Attribution 4.0 International

19 October 2023

language of work or name

English

0 references

publication date

2008

0 references

0 references

0 references

0 references

e4046

0 references

start time

24 December 2008

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

describes a project that uses

ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2603313/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

The low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

A GSK3beta phosphorylation site in axin modulates interaction with beta-catenin and Tcf-mediated gene expression

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

A single BIR domain of XIAP sufficient for inhibiting caspases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

A mechanism for Wnt coreceptor activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Target protease specificity of the viral serpin CrmA. Analysis of five caspases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Mechanisms of Wnt signaling in development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

β-catenin is a target for the ubiquitin–proteasome pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

LRP6 mutation in a family with early coronary disease and metabolic risk factors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Multiplicity of the interactions of Wnt proteins and their receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Role of the intracellular domains of LRP5 and LRP6 in activating the Wnt canonical pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Regulation of protein kinases in insulin, growth factor and Wnt signalling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Identification of the Axin and Frat binding region of glycogen synthase kinase-3.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Domains of axin and disheveled required for interaction and function in wnt signaling.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Accumulation of Armadillo Induced by Wingless, Dishevelled, and Dominant-negative Zeste-white 3 Leads to Elevated DE-cadherin inDrosophila Clone 8 Wing Disc Cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

A major developmental transition in early xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Armadillo/beta-catenin signals in the nucleus--proof beyond a reasonable doubt?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2603313

A role of Dishevelled in relocating Axin to the plasma membrane during wingless signaling.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004046

Serine Phosphorylation-regulated Ubiquitination and Degradation of β-Catenin

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19107203

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dorsal downregulation of GSK3beta by a non-Wnt-like mechanism is an early molecular consequence of cortical rotation in early Xenopus embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/19107203

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0004046

1 reference

release_lmiyifrgwzaejkligpwhnsqb24

0 references

0 references

3211583

1 reference

1 reference

3211583

1 reference