Effects of the missense mutations in canine BRCA2 on BRC repeat 3 functions and comparative analyses between canine and human BRC repeat 3 (Q34446882)

2 August 2017

title

Effects of the missense mutations in canine BRCA2 on BRC repeat 3 functions and comparative analyses between canine and human BRC repeat 3 (English)

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2 August 2017

Yasunaga Yoshikawa

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2 August 2017

Kazuhiko Ochiai

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2 August 2017

Masami Morimatsu

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2 August 2017

Yu Suzuki

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2 August 2017

Seiichi Wada

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2 August 2017

Takahiro Taoda

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2 August 2017

Satomi Iwai

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2 August 2017

Seishiro Chikazawa

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2 August 2017

Koichi Orino

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2 August 2017

Kiyotaka Watanabe

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2 August 2017

language of work or name

English

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publication date

12 October 2012

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2 August 2017

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

e45833

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Creative Commons Attribution 4.0 International

2 August 2017

start time

12 October 2012

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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1 reference

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Canine tumors: a spontaneous animal model of human carcinogenesis

6 July 2018

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BRCA1 and BRCA2: different roles in a common pathway of genome protection

6 July 2018

1 reference

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Breast cancer statistics, 2011.

6 July 2018

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Two classes of BRC repeats in BRCA2 promote RAD51 nucleoprotein filament function by distinct mechanisms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

Valine 1532 of human BRC repeat 4 plays an important role in the interaction between BRCA2 and RAD51

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

Molecular carcinogenesis of canine mammary tumors: news from an old disease

6 July 2018

1 reference

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Molecular Biological Aspects on Canine and Human Mammary Tumors

6 July 2018

1 reference

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Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase.

6 July 2018

1 reference

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Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment

6 July 2018

1 reference

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Penetrance estimates for BRCA1 and BRCA2 based on genetic testing in a Clinical Cancer Genetics service setting: risks of breast/ovarian cancer quoted should reflect the cancer burden in the family

6 July 2018

1 reference

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Incidence of and survival after mammary tumors in a population of over 80,000 insured female dogs in Sweden from 1995 to 2002.

6 July 2018

1 reference

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UCSF Chimera--a visualization system for exploratory research and analysis

6 July 2018

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Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

The BRC repeats are conserved in mammalian BRCA2 proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

6 July 2018

Canine mammary tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

Single nucleotide variation in exon 11 of canine BRCA2 in healthy and cancerous mammary tissue

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

Mammary tumor development in dogs is associated with BRCA1 and BRCA2.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

Analysis of genetic variations in the exon 27 region of the canine BRCA2 locus.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

Population-based incidence of mammary tumours in some dog breeds.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

Cloning and sequencing full length of canine Brca2 and Rad51 cDNA.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

Canine mammary epithelial neoplasms: biologic implications of morphologic characteristics assessed in 232 dogs.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3470543

Mammary tumors in a colony of beagle dogs

27 October 2018

1 reference

12 December 2020

Insertion/deletion polymorphism in the BRCA2 nuclear localization signal

1 reference

12 December 2020

Inhibition of filament formation of human Rad51 protein by a small peptide derived from the BRC-motif of the BRCA2 protein

1 reference

12 December 2020

Novel variations and loss of heterozygosity of BRCA2 identified in a dog with mammary tumors

1 reference

12 December 2020

Cancer-associated mutations in BRC domains of BRCA2 affect homologous recombination induced by Rad51

1 reference

12 December 2020

Interactions between canine RAD51 and full length or truncated BRCA2 BRC repeats

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0045833

Identifiers

DOI

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2 August 2017

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2 August 2017

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