Canine tumors: a spontaneous animal model of human carcinogenesis (Q37984855)

26 August 2017

title

Canine tumors: a spontaneous animal model of human carcinogenesis (English)

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26 August 2017

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Salomé Soares de Pinho

series ordinal

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26 August 2017

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26 August 2017

Sandra Carvalho

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26 August 2017

Joana Cabral

series ordinal

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26 August 2017

Fátima Gärtner

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26 August 2017

publication date

21 December 2011

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26 August 2017

published in

Translational Research

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26 August 2017

volume

159

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26 August 2017

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26 August 2017

page(s)

165-172

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Modeling Opportunities in Comparative Oncology for Drug Development

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Widespread intraspecies cross-contamination of human tumor cell lines arising at source.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

HeLa cells 50 years on: the good, the bad and the ugly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Mouse xenograft models vs GEM models for human cancer therapeutics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Spontaneous and genetically engineered animal models; use in preclinical cancer drug development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Lost in translation: problems and pitfalls in translating laboratory observations to clinical utility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Trials, tribulations, and trends in tumor modeling in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Developmental and tissue-specific regulation of mouse telomerase and telomere length

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

In vivo/ex vivo and in situ assays used in cancer research: a brief review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Spontaneous tumors in dogs and cats: models for the study of cancer biology and treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Spontaneously occurring tumors of companion animals as models for human cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Comparative oncology today

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

The dog as a cancer model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Translation of new cancer treatments from pet dogs to humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

The dog genome: survey sequencing and comparative analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Genome sequence, comparative analysis and haplotype structure of the domestic dog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Comparative expression pathway analysis of human and canine mammary tumors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Reactive oxygen species and HIF-1 signalling in cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

The phosphatidyl inositol 3-kinase/AKT signaling pathway in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

The phosphatidyl inositol 3-kinase signaling network: implications for human breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Reduced PTEN protein expression and its prognostic implications in canine and feline mammary tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Wnt signaling: a common theme in animal development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Wnt signalling and its impact on development and cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

cDNA microarray profiles of canine mammary tumour cell lines reveal deregulated pathways pertaining to their phenotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Targeting the mitogen-activated protein kinase cascade to treat cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Clinical management of women with genomic BRCA1 and BRCA2 mutations.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Overexpression of BRCA2 gene in sporadic breast tumours.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Over-expression of wild-type Rad51 correlates with histological grading of invasive ductal breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Increased expression of BRCA2 and RAD51 in lymph node metastases of canine mammary adenocarcinomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

BRCA1 expression in canine mammary dysplasias and tumours: relationship with prognostic variables

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Estrogens, regulation of p53 and breast cancer risk: a balancing act.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Differential expression of cell cycle regulators p21, p27 and p53 in metastasizing canine mammary adenocarcinomas versus normal mammary glands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Renovation of a drop embryo cultures system by using refined mineral oil and the effect of glucose and/or hemoglobin added to a serum-free medium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Aberrations of the p53 tumor suppressor gene in various tumors in dogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Estrogen Receptors as Therapeutic Targets in Breast Cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Steroid receptors and their role in the biology and control of breast cancer growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

The use of selective estrogen receptor modulators and selective estrogen receptor down-regulators in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

A prospective analysis of immunohistochemically determined estrogen receptor alpha and progesterone receptor expression and host and tumor factors as predictors of disease-free period in mammary tumors of the dog.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Immunohistochemical study of hormonal receptors and cell proliferation in normal canine mammary glands and spontaneous mammary tumours

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Immunohistologic detection of estrogen receptor alpha in canine mammary tumors: clinical and pathologic associations and prognostic significance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Molecular plasticity of E-cadherin and sialyl lewis x expression, in two comparative models of mammary tumorigenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Molecular mechanisms controlling E-cadherin expression in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Prognostic factors associated with survival two years after surgery in dogs with malignant mammary tumors: 79 cases (1998-2002)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Prognostic factors in canine mammary tumors: a multivariate study of 202 consecutive cases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

E-cadherin, beta-catenin, invasion and lymph node metastases in canine malignant mammary tumours

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Expression of E-cadherin, P-cadherin and beta-catenin in canine malignant mammary tumours in relation to clinicopathological parameters, proliferation and survival.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

E-cadherin expression in canine malignant mammary tumours: relationship to other clinico-pathological variables

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

P-cadherin expression in breast cancer: a review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

P-Cadherin Expression in Canine Mammary Tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Epidermal growth factor receptor in triple-negative and basal-like breast cancer: promising clinical target or only a marker?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

EGFR signaling in breast cancer: bad to the bone.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Immunohistochemical expression of Epidermal Growth Factor Receptor (EGFR) in canine mammary tissues.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Expression of epidermal growth factor receptor (EGFR) in non-affected and tumorous mammary tissue of female dogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Canine mammary gland tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

7 January 2021

Cancer statistics, 2007

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Modeling metastasis in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Cancer susceptibility and the functions of BRCA1 and BRCA2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

P53 transcriptional activities: a general overview and some thoughts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Using the canine genome to cure cancer and other diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Evaluation of hormone receptor expression for use in predicting survival of female dogs with malignant mammary gland tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Cellular expression of estrogen and progesterone receptors in mammary glands: regulation by hormones, development and aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Sialyl Lewis x expression in canine malignant mammary tumours: correlation with clinicopathological features and E-Cadherin expression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Coordinated expression of galectin-3 and galectin-3-binding sites in malignant mammary tumors: implications for tumor metastasis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Role of E-cadherin N-glycosylation profile in a mammary tumor model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Dog models of naturally occurring cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Guiding the optimal translation of new cancer treatments from canine to human cancer patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Clinical trials going to the dogs: canine program to study tumor treatment, biology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Preclinical investigation of PEGylated tumor necrosis factor alpha in dogs with spontaneous tumors: phase I evaluation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

Signal transduction by receptors with tyrosine kinase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

The biology of signal transduction inhibition: basic science to novel therapies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

The Comparative Oncology Trials Consortium: using spontaneously occurring cancers in dogs to inform the cancer drug development pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2011.11.005

10.1016/J.TRSL.2011.11.005

7 January 2021

Identifiers

DOI

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26 August 2017

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