Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy (Q34313853)

1 August 2017

title

Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy (English)

1 reference

1 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854827

16 July 2024

gene delivery

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16 July 2024

author name string

Ganapathy Jagatheesan

1 reference

1 August 2017

Federica del Monte

1 reference

1 August 2017

James R. Peña

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854827

16 July 2024

Ariani C. Szkudlarek

1 reference

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16 July 2024

Chad M. Warren

1 reference

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16 July 2024

Lynley S. Heinrich

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16 July 2024

Robert D. Gaffin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854827

16 July 2024

Roger J. Hajjar

1 reference

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16 July 2024

Paul H. Goldspink

1 reference

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16 July 2024

R. John Solaro

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854827

16 July 2024

David F. Wieczorek

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854827

16 July 2024

Beata M. Wolska

1 reference

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16 July 2024

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20854827

16 July 2024

publication date

18 September 2010

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full work available at URL

1 August 2017

https://europepmc.org/articles/pmc2982190?pdf=render

file format

Portable Document Format

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854827

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20854827/pdf/?tool=EBI

16 July 2024

file format

Portable Document Format

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854827

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20854827/?tool=EBI

16 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854827

https://europepmc.org/articles/PMC2982190

16 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854827

https://europepmc.org/articles/PMC2982190?pdf=render

16 July 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854827

https://doi.org/10.1016/j.yjmcc.2010.09.010

16 July 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854827

https://api.elsevier.com/content/article/PII:S002228281000341X?httpAccept=text/xml

16 July 2024

1 reference

10.1016/J.YJMCC.2010.09.010

DOI

https://api.crossref.org/works/10.1016/J.YJMCC.2010.09.010

https://api.elsevier.com/content/article/PII:S002228281000341X?httpAccept=text/plain

16 July 2024

1 reference

10.1016/J.YJMCC.2010.09.010

DOI

https://api.crossref.org/works/10.1016/J.YJMCC.2010.09.010

Journal of Molecular and Cellular Cardiology

16 July 2024

published in

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1 August 2017

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1 August 2017

1 reference

1 August 2017

page(s)

993-1002

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Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure

1 August 2017

cites work

1 reference

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Titin-based mechanical signalling in normal and failing myocardium

6 July 2018

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Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial.

6 July 2018

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Use of 2-D DIGE analysis reveals altered phosphorylation in a tropomyosin mutant (Glu54Lys) linked to dilated cardiomyopathy

6 July 2018

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Sarcomeric proteins and familial hypertrophic cardiomyopathy: linking mutations in structural proteins to complex cardiovascular phenotypes

6 July 2018

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6 July 2018

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Expression of slow skeletal troponin I in adult mouse heart helps to maintain the left ventricular systolic function during respiratory hypercapnia

6 July 2018

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Assessing the risk of sudden cardiac death in a patient with hypertrophic cardiomyopathy

6 July 2018

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At the crossroads of myocardial signaling: the role of Z-discs in intracellular signaling and cardiac function.

6 July 2018

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Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy

6 July 2018

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The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model

6 July 2018

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Hypertrophic cardiomyopathy: a systematic review

6 July 2018

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Enhancement of L-type Ca(2+) current from neonatal mouse ventricular myocytes by constitutively active PKC-betaII

6 July 2018

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Targeting phospholamban by gene transfer in human heart failure

6 July 2018

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Expression of slow skeletal troponin I in adult transgenic mouse heart muscle reduces the force decline observed during acidic conditions

6 July 2018

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Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failure

6 July 2018

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Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy

6 July 2018

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SERCA pump level is a critical determinant of Ca(2+)homeostasis and cardiac contractility

6 July 2018

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The Genetic Basis for Cardiomyopathy

6 July 2018

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Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy

6 July 2018

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Phospholamban and cardiac contractile function

6 July 2018

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Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure

6 July 2018

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High-efficiency, long-term cardiac expression of foreign genes in living mouse embryos and neonates.

6 July 2018

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Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy

6 July 2018

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Targeted overexpression of the sarcoplasmic reticulum Ca2+-ATPase increases cardiac contractility in transgenic mouse hearts

6 July 2018

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Sarcoplasmic reticulum gene expression in cardiac hypertrophy and heart failure.

6 July 2018

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Recirculating cardiac delivery of AAV2/1SERCA2a improves myocardial function in an experimental model of heart failure in large animals

6 July 2018

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Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure.

28 October 2018

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Percutaneous cardiac recirculation-mediated gene transfer of an inhibitory phospholamban peptide reverses advanced heart failure in large animals

28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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Doxycycline inducible expression of SERCA2a improves calcium handling and reverts cardiac dysfunction in pressure overload-induced cardiac hypertrophy

28 October 2018

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Parvalbumin corrects slowed relaxation in adult cardiac myocytes expressing hypertrophic cardiomyopathy-linked alpha-tropomyosin mutations

28 October 2018

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Troponin I phosphorylation plays an important role in the relaxant effect of beta-adrenergic stimulation in mouse hearts

28 October 2018

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28 October 2018

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A mouse model of familial hypertrophic cardiomyopathy caused by a alpha-tropomyosin mutation

28 October 2018

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Troponin I in the murine myocardium: influence on length-dependent activation and interfilament spacing

28 October 2018

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Akt signaling mediates postnatal heart growth in response to insulin and nutritional status

28 October 2018

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Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery

28 October 2018

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Expression of slow skeletal troponin I in hearts of phospholamban knockout mice alters the relaxant effect of beta-adrenergic stimulation

28 October 2018

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Transgenic expression of sarcoplasmic reticulum Ca(2+) atpase modifies the transition from hypertrophy to early heart failure

28 October 2018

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The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms

28 October 2018

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Relationship between Na+-Ca2+-exchanger protein levels and diastolic function of failing human myocardium

28 October 2018

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Sudden death in young competitive athletes. Clinical, demographic, and pathological profiles.

28 October 2018

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The effect of myosin regulatory light chain phosphorylation on the frequency-dependent regulation of cardiac function

28 October 2018

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A familial hypertrophic cardiomyopathy alpha-tropomyosin mutation causes severe cardiac hypertrophy and death in mice

28 October 2018

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Microarray analysis of gene expression during early stages of mild and severe cardiac hypertrophy

7 January 2021

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Contractile systolic and diastolic dysfunction in renin-induced hypertensive cardiomyopathy

7 January 2021

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Effect of ablation of phospholamban on dynamics of cardiac myocyte contraction and intracellular Ca2+

7 January 2021

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Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.09.010

Overwhelming evidence of the beneficial effects of SERCA gene transfer in heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.09.010

Beta-adrenergic receptor stimulation increases unloaded shortening velocity of skinned single ventricular myocytes from rats

7 January 2021

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Atrial natriuretic factor gene expression in rat ventricle during experimental hypertension

7 January 2021

1 reference

12 December 2020

Isoproterenol infusion induces alterations in expression of hypertrophy-associated genes in rat heart

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12 December 2020

Human heart failure: cAMP stimulation of SR Ca(2+)-ATPase activity and phosphorylation level of phospholamban

1 reference

12 December 2020

Rescue of tropomyosin-induced familial hypertrophic cardiomyopathy mice by transgenesis

1 reference

12 December 2020

Altered hemodynamics in transgenic mice harboring mutant tropomyosin linked to hypertrophic cardiomyopathy

1 reference

12 December 2020

10.1016/J.YJMCC.2010.09.010

Identifiers

DOI

1 reference

1 August 2017

1 reference

1 August 2017

1 reference