Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin. (Q34312771)

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16 January 2020

title

Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin (English)

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16 January 2020

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16 January 2020

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16 January 2020

Yifeng Li

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16 January 2020

Wei Jin

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16 January 2020

Chunhong Shao

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16 January 2020

Congjian Xu

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16 January 2020

Haihui Sheng

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16 January 2020

Yan Liu

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16 January 2020

Jinde Yu

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16 January 2020

Yuying Xie

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16 January 2020

Yingnan Zhao

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16 January 2020

Daru Lu

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16 January 2020

Daniel W Nebert

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16 January 2020

Donald C Harrison

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16 January 2020

Wei Huang

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16 January 2020

Li Jin

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16 January 2020

language of work or name

English

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publication date

26 January 2006

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Journal of Clinical Investigation

16 January 2020

published in

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volume

116

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issue

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16 January 2020

page(s)

506-511

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An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation

16 January 2020

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Contribution of aldehyde dehydrogenase to mitochondrial bioactivation of nitroglycerin: evidence for the activation of purified soluble guanylate cyclase through direct formation of nitric oxide.

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The mutation in the mitochondrial aldehyde dehydrogenase (ALDH2) gene responsible for alcohol-induced flushing increases turnover of the enzyme tetramers in a dominant fashion

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Investigator-observed alcohol-induced flushing but not self-report of flushing is a valid predictor of ALDH2 genotype

6 July 2018

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Effects of changing glutamate 487 to lysine in rat and human liver mitochondrial aldehyde dehydrogenase. A model to study human (Oriental type) class 2 aldehyde dehydrogenase

6 July 2018

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Investigation of the active site cysteine residue of rat liver mitochondrial aldehyde dehydrogenase by site-directed mutagenesis.

6 July 2018

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Involvement of glutamate 268 in the active site of human liver mitochondrial (class 2) aldehyde dehydrogenase as probed by site-directed mutagenesis

6 July 2018

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The aldehyde dehydrogenase ALDH2*2 allele exhibits dominance over ALDH2*1 in transduced HeLa cells

6 July 2018

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12 December 2020

Identifiers

DOI

10.1172/JCI26564

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16 January 2020

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16 January 2020

PubMed publication ID

16440063

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