An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation (Q24535741)

19 October 2023

Zhiqiang Chen

Zhiqiang

Chen

1 reference

19 October 2023

Matthew W Foster

Matthew W

Foster

1 reference

19 October 2023

Jian Zhang

Jian

Zhang

1 reference

19 October 2023

Lan Mao

Lan

Mao

1 reference

19 October 2023

Howard A Rockman

Howard A

Rockman

1 reference

19 October 2023

Toshihiro Kawamoto

Toshihiro

Kawamoto

1 reference

19 October 2023

Keiichi I Nakayama

Keiichi I

Nakayama

1 reference

19 October 2023

Douglas T Hess

Douglas T

Hess

1 reference

19 October 2023

Jonathan S Stamler

Jonathan S

Stamler

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 October 2023

language of work or name

English

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publication date

23 August 2005

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published in

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volume

102

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issue

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page(s)

12159-64

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cites work

Glutathione S-transferase mu polymorphism does not explain variation in nitroglycerin responsiveness

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Molecular abnormality and cDNA cloning of human aldehyde dehydrogenases

7 April 2017

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Differential nitros(yl)ation of blood and tissue constituents during glyceryl trinitrate biotransformation in vivo

24 March 2017

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Nitrates and NO release: contemporary aspects in biological and medicinal chemistry.

27 September 2017

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Contribution of aldehyde dehydrogenase to mitochondrial bioactivation of nitroglycerin: evidence for the activation of purified soluble guanylate cyclase through direct formation of nitric oxide.

27 September 2017

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Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance.

27 September 2017

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Nitrate tolerance, oxidative stress, and mitochondrial function: another worrisome chapter on the effects of organic nitrates

27 September 2017

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Biochemical mechanism of nitroglycerin action and tolerance: is this old mystery solved?

27 September 2017

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Clinical pharmacokinetics and pharmacodynamics of glyceryl trinitrate and its metabolites

27 September 2017

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After 130 years, the molecular mechanism of action of nitroglycerin is revealed

27 September 2017

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Identification of the enzymatic mechanism of nitroglycerin bioactivation

27 September 2017

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Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations

27 September 2017

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Biotransformation of glyceryl trinitrate and isosorbide dinitrate in vascular smooth muscle made tolerant to organic nitrates

27 September 2017

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Incidence of early tolerance to hemodynamic effects of continuous infusion of nitroglycerin in patients with coronary artery disease and heart failure.

27 September 2017

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Biphasic relaxant curves to glyceryl trinitrate in rat aortic rings. Evidence for two mechanisms of action

30 May 2018

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Nitrite as the major source of nitric oxide production by Arabidopsis thaliana in response to Pseudomonas syringae

30 May 2018

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Oxidative stress and mitochondrial aldehyde dehydrogenase activity: a comparison of pentaerythritol tetranitrate with other organic nitrates

29 November 2018

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Role of mitochondrial aldehyde dehydrogenase in nitroglycerin-induced vasodilation of coronary and systemic vessels: an intact canine model

29 November 2018

1 reference

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Relationship between cyclic guanosine 3':5'-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin

29 November 2018

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Aldehyde dehydrogenase (ALDH) 2 associates with oxidation of methoxyacetaldehyde; in vitro analysis with liver subcellular fraction derived from human and Aldh2 gene targeting mouse

29 November 2018

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12 December 2020

Biotransformation of organic nitrates and vascular smooth muscle cell function

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12 December 2020

Identification of a 54-kDa mitochondrial acetaminophen-binding protein as aldehyde dehydrogenase

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12 December 2020

Long-term nitrate use may be deleterious in ischemic heart disease: A study using the databases from two large-scale postinfarction studies. Multicenter Myocardial Ischemia Research Group

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12 December 2020

Nitroglycerin tolerance in human vessels: evidence for impaired nitroglycerin bioconversion

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0503723102

1 reference

release_fb5usuoslfeuxa6dsipcpz6y6y

0 references

0 references

1808319

1 reference

1 reference

1808319

1 reference