Avoiding Barriers to PET Radioligand Development: Cellular Assays of Brain Efflux Transporters (Q34285225)

1 August 2017

title

Avoiding barriers to PET radioligand development: cellular assays of brain efflux transporters (English)

1 reference

1 August 2017

Avoiding Barriers to PET Radioligand Development: Cellular Assays of Brain Efflux Transporters (English)

1 reference

10.2967/JNUMED.110.081125

Crossref

DOI

https://api.crossref.org/works/10.2967/JNUMED.110.081125

24 November 2024

Matthew D. Hall

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21321273

24 November 2024

Victor W. Pike

series ordinal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21321273

24 November 2024

language of work or name

English

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publication date

14 February 2011

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full work available at URL

1 August 2017

https://jnm.snmjournals.org/content/jnumed/52/3/338.full.pdf

file format

Portable Document Format

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21321273

http://jnm.snmjournals.org/cgi/content/abstract/52/3/338

24 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21321273

https://europepmc.org/articles/PMC4184239

24 November 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21321273

https://europepmc.org/articles/PMC4184239?pdf=render

24 November 2024

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Portable Document Format

content deliverer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21321273

https://doi.org/10.2967/jnumed.110.081125

24 November 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21321273

https://syndication.highwire.org/content/doi/10.2967/jnumed.110.081125

24 November 2024

1 reference

10.2967/JNUMED.110.081125

Crossref

DOI

https://api.crossref.org/works/10.2967/JNUMED.110.081125

The Journal of Nuclear Medicine

24 November 2024

published in

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

338-340

1 reference

Transport of selected PET radiotracers by human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2): an in vitro screening.

1 August 2017

cites work

1 reference

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P-glycoprotein function at the blood-brain barrier in humans can be quantified with the substrate radiotracer 11C-N-desmethyl-loperamide

6 July 2018

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The role of the blood-CNS barrier in CNS disorders and their treatment

6 July 2018

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Imaging the function of P-glycoprotein with radiotracers: pharmacokinetics and in vivo applications

6 July 2018

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PET radiotracers: crossing the blood-brain barrier and surviving metabolism

6 July 2018

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Species differences in blood-brain barrier transport of three positron emission tomography radioligands with emphasis on P-glycoprotein transport

6 July 2018

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In vivo site-directed radiotracers: a mini-review

6 July 2018

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Blood-brain barrier permeability considerations for CNS-targeted compound library design

6 July 2018

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11C-loperamide and its N-desmethyl radiometabolite are avid substrates for brain permeability-glycoprotein efflux

6 July 2018

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P-glycoprotein recognition of substrates and circumvention through rational drug design

6 July 2018

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Positron emission tomography studies on binding of central nervous system drugs and P-glycoprotein function in the rodent brain.

6 July 2018

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Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184239

PET Studies on P-glycoprotein function in the blood-brain barrier: how it affects uptake and binding of drugs within the CNS.

6 July 2018

1 reference

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Determination of lipophilicity and its use as a predictor of blood-brain barrier penetration of molecular imaging agents

6 July 2018

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Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography

6 July 2018

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In vivo evaluation of P-glycoprotein modulation of 8 PET radioligands used clinically.

6 July 2018

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Effect of a P-glycoprotein inhibitor, Cyclosporin A, on the disposition in rodent brain and blood of the 5-HT1A receptor radioligand, [11C](R)-(-)-RWAY.

28 October 2018

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Quantitative analysis of 11C-verapamil transfer at the human blood-brain barrier for evaluation of P-glycoprotein function.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184239

Quantification of serotonin 5-HT1A receptors in monkey brain with [11C](R)-(-)-RWAY.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184239

Influence of P-glycoprotein on brain uptake of [18F]MPPF in rats

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21321273

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Positron-emitting radioligands for studies in vivo-probes for human psychopharmacology

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21321273

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2967/JNUMED.110.081125

1 reference

1 August 2017

1 reference

1 August 2017

1 reference