Positron emission tomography studies on binding of central nervous system drugs and P-glycoprotein function in the rodent brain. (Q36136731)

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English	Positron emission tomography studies on binding of central nervous system drugs and P-glycoprotein function in the rodent brain.	scientific article

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PubMed publication ID

15912274

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

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12 January 2020

review article

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title

Positron emission tomography studies on binding of central nervous system drugs and P-glycoprotein function in the rodent brain (English)

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Europe PubMed Central

PubMed publication ID

15912274

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12 January 2020

main subject

positron emission tomography

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Joost Bart

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3

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PubMed publication ID

15912274

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12 January 2020

N. Harry Hendrikse

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2

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N Harry Hendrikse

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Europe PubMed Central

PubMed publication ID

15912274

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12 January 2020

Philip H. Elsinga

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Philip H Elsinga

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Europe PubMed Central

PubMed publication ID

15912274

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12 January 2020

author name string

Aren van Waarde

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4

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Europe PubMed Central

PubMed publication ID

15912274

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12 January 2020

Willem Vaalburg

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5

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PubMed publication ID

15912274

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publication date

1 January 2005

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PubMed publication ID

15912274

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12 January 2020

published in

Molecular Imaging and Biology

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PubMed publication ID

15912274

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12 January 2020

volume

7

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PubMed publication ID

15912274

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12 January 2020

issue

1

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PubMed publication ID

15912274

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12 January 2020

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37-44

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PubMed publication ID

15912274

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12 January 2020

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(S,S)- and (S,R)-1'-[18F]fluorocarazolol, ligands for the visualization of pulmonary beta-adrenergic receptors with PET.

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Preparation and in vivo binding of [11C]carazolol, a radiotracer for the beta-adrenergic receptor

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12 December 2020

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How does P-glycoprotein recognize its substrates?

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Quantitative assessment of P-glycoprotein function in the rat blood-brain barrier by distribution volume of [11C]verapamil measured with PET.

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P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

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Carbon-11-labeled daunorubicin and verapamil for probing P-glycoprotein in tumors with PET.

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Copper bis(diphosphine) complexes: radiopharmaceuticals for the detection of multi-drug resistance in tumours by PET.

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Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines

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The physiological function of drug-transporting P-glycoproteins

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Reversal of chloroquine resistance in Plasmodium falciparum by verapamil

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12 December 2020

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P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain

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12 December 2020

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Metabolism of carvedilol in man

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12 December 2020

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Adjuvant treatment with cyclosporin A increases the toxicity of chemotherapy for remission induction in acute non-lymphocytic leukemia

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12 December 2020

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Modulation of doxorubicin concentration by cyclosporin A in brain and testicular barrier tissues expressing P-glycoprotein in rats

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12 December 2020

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The interaction of some centrally active drugs with the blood-brain barrier and circumventricular organs

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12 December 2020

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What is the blood-brain barrier? A molecular perspective. Cerebral vascular biology.

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Phase I and pharmacokinetic study of paclitaxel in combination with biricodar, a novel agent that reverses multidrug resistance conferred by overexpression of both MDR1 and MRP.

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Biochemistry of multidrug resistance mediated by the multidrug transporter

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The Functional Role of P-Glycoprotein in the Blood–Brain Barrier

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Reversal of multidrug resistance by lipophilic drugs.

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Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity.

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Structural characteristics of compounds that modulate P-glycoprotein-associated multidrug resistance

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Chronic reserpine administration selectively up-regulates beta 1- and alpha 1b-adrenergic receptors in rat brain: an autoradiographic study

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Relationship between lipophilicity and brain extraction of C-11-labeled radiopharmaceuticals

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What have we learnt thus far from mice with disrupted P-glycoprotein genes?

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Biodistribution, radiation dose estimates, and in vivo Pgp modulation studies of 18F-paclitaxel in nonhuman primates

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Pharmacogenetics of the human drug-transporter gene MDR1: impact of polymorphisms on pharmacotherapy

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Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

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12 December 2020

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Validation of S-1'-[18F]fluorocarazolol for in vivo imaging and quantification of cerebral beta-adrenoceptors

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15912274

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12 December 2020

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Increase in doxorubicin cytotoxicity by carvedilol inhibition of P-glycoprotein activity

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PubMed

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12 December 2020

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The physiology of the blood-brain barrier.

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12 December 2020

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The blood-brain barrier: principles for targeting peptides and drugs to the central nervous system

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12 December 2020

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Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

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PubMed

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12 December 2020

based on heuristic

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Safety and efficacy of the multidrug resistance inhibitor Incel (biricodar; VX-710) in combination with paclitaxel for advanced breast cancer refractory to paclitaxel

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12 December 2020

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Enhanced cerebral uptake of receptor ligands by modulation of P-glycoprotein function in the blood-brain barrier

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12 December 2020

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P-Glycoprotein on astrocyte foot processes of unfixed isolated human brain capillaries

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12 December 2020

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Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).

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12 December 2020

based on heuristic

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Evaluation of 11C-colchicine for PET imaging of multiple drug resistance.

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12 December 2020

based on heuristic

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Characterization of a rat retinal endothelial cell culture and the expression of P-glycoprotein in brain and retinal endothelium in vitro

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12 December 2020

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Evaluation of carbon-14-colchicine biodistribution with whole-body quantitative autoradiography in colchicine-sensitive and -resistant xenografts

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of P-glycoprotein on brain uptake of [18F]MPPF in rats

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12 December 2020

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inferred from PubMed ID database lookup

A new in vivo method to study P-glycoprotein transport in tumors and the blood-brain barrier

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carazolol, an extremely potent β-adrenergic blocker: Binding to β-receptors in brain membranes

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PubMed

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12 December 2020

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Genetic polymorphism in MDR-1: a tool for examining allelic expression in normal cells, unselected and drug-selected cell lines, and human tumors.

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12 December 2020

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inferred from PubMed ID database lookup

Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance.

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I study of etoposide with SDZ PSC 833 as a modulator of multidrug resistance in patients with cancer

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance to anthrapyrazoles and anthracyclines in multidrug-resistant P388 murine leukemia cells: reversal by calcium blockers and calmodulin antagonists.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transporting therapeutics across the blood-brain barrier

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: a Southwest Oncology Group study

1 reference

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https://pubmed.ncbi.nlm.nih.gov/15912274

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional involvement of P-glycoprotein in blood-brain barrier

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and evaluation of radiolabeled antagonists for imaging of beta-adrenoceptors in the brain with PET.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The blood-brain barrier

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of drugs with P-glycoprotein in brain capillaries

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete in vivo reversal of P-glycoprotein pump function in the blood-brain barrier visualized with positron emission tomography

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and biodistribution of a Lipophilic 64Cu-labeled monocationic Copper(II) complex.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specialized localization of P-glycoprotein recognized by MRK 16 monoclonal antibody in endothelial cells of the brain and the spinal cord

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Octanol-water partition: searching for predictive models

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15912274

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The blood-brain barrier and oncology: new insights into function and modulation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imaging beta-adrenoceptors in the human brain with (S)-1'-[18F]fluorocarazolol.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The P-Glycoprotein Efflux Pump: How Does it Transport Drugs?

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain microvascular P-glycoprotein and a revised model of multidrug resistance in brain

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of multidrug transporters in pharmacoresistance to antiepileptic drugs

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15912274

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S11307-005-0951-X

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15912274

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 January 2020

PubMed publication ID

15912274

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15912274

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15912274%20AND%20SRC:MED&resulttype=core&format=json

retrieved

12 January 2020

ResearchGate publication ID

7829965

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