The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination (Q34263084)

1 August 2017

title

The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination (English)

1 reference

1 August 2017

Tasuku Honjo

1 reference

1 August 2017

Andre Stanlie

1 reference

1 August 2017

Nasim A Begum

series ordinal

1 reference

1 August 2017

Hideo Akiyama

series ordinal

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1 August 2017

publication date

26 April 2012

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1 August 2017

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

e1002675

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Creative Commons Attribution 4.0 International

1 August 2017

start time

26 April 2012

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

cites work

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Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination

28 July 2018

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Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes

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Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5

28 July 2018

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AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination

28 July 2018

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28 July 2018

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Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction

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RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

28 July 2018

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S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase

28 July 2018

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IgH class switching and translocations use a robust non-classical end-joining pathway

28 July 2018

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Activation-induced cytidine deaminase initiates immunoglobulin gene conversion and hypermutation by a common intermediate

28 July 2018

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C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

28 July 2018

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Transcription elongation factors repress transcription initiation from cryptic sites.

28 July 2018

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NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila

28 July 2018

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R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

28 July 2018

1 reference

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Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

28 July 2018

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28 July 2018

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28 July 2018

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AID is essential for immunoglobulin V gene conversion in a cultured B cell line

28 July 2018

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Molecular mechanism of class switch recombination: linkage with somatic hypermutation

28 July 2018

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Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion

28 July 2018

1 reference

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28 July 2018

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

28 July 2018

1 reference

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Ku80 is required for immunoglobulin isotype switching

28 July 2018

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Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae

28 July 2018

1 reference

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DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

28 July 2018

1 reference

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A human RNA polymerase II complex associated with SRB and DNA-repair proteins

28 July 2018

1 reference

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DNA sequences at immunoglobulin switch region recombination sites

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3343088

Shutdown of class switch recombination by deletion of a switch region control element.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3343088

A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon

28 July 2018

1 reference

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Mutations affecting Ty-mediated expression of the HIS4 gene of Saccharomyces cerevisiae

28 July 2018

1 reference

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Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3343088

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3343088

Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells.

28 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

Switch region of immunoglobulin Cmu gene is composed of simple tandem repetitive sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

The involvement of non-B DNA structures in gross chromosomal rearrangements

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

Genome-wide analysis reveals novel molecular features of mouse recombination hotspots

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

Analysis of polymerase II elongation complexes by native gel electrophoresis. Evidence for a novel carboxyl-terminal domain-mediated termination mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

Controlling histone methylation via trans-histone pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

Role of human transcription elongation factor DSIF in the suppression of senescence and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

Ikaros controls isotype selection during immunoglobulin class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

RSSsite: a reference database and prediction tool for the identification of cryptic Recombination Signal Sequences in human and murine genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

V(D)J recombinase binding and cleavage of cryptic recombination signal sequences identified from lymphoid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002675

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22570620

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Homologous recombination repair is regulated by domains at the N- and C-terminus of NBS1 and is dissociated with ATM functions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22570620

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1002675

1 reference

1 August 2017

1 reference

1 August 2017

1 reference