Targeting Notch signaling pathway to overcome drug resistance for cancer therapy (Q34205088)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20600632%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

review article

1 reference

title

Targeting Notch signaling pathway to overcome drug resistance for cancer therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20600632%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20600632%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20600632%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Fazlul H Sarkar

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20600632%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Zhiwei Wang

1 reference

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7 February 2020

Yiwei Li

series ordinal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20600632%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Sanjeev Banerjee

series ordinal

1 reference

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7 February 2020

Dejuan Kong

series ordinal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20600632%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

language of work or name

English

0 references

publication date

22 June 2010

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Biochimica et Biophysica Acta

7 February 2020

published in

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7 February 2020

volume

1806

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7 February 2020

issue

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7 February 2020

page(s)

258-267

1 reference

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Created Gli-1 duplex short-RNA (i-Gli-RNA) eliminates CD44 Hi progenitors of taxol-resistant ovarian cancer cells

7 February 2020

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1 reference

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Implication of microRNAs in drug resistance for designing novel cancer therapy

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28 July 2018

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Cyclo-oxygenase 2 up-regulates the effect of multidrug resistance

28 July 2018

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28 July 2018

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28 July 2018

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The role of KRAS mutations in resistance to EGFR inhibition in the treatment of cancer.

28 July 2018

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Inhibition of Notch3 enhances sensitivity to gemcitabine in pancreatic cancer through an inactivation of PI3K/Akt-dependent pathway

28 July 2018

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Role of Notch signaling in colorectal cancer

28 July 2018

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Emerging role of Notch signaling in epidermal differentiation and skin cancer

28 July 2018

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Resistance pathways relevant to insulin-like growth factor-1 receptor-targeted therapy.

28 July 2018

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Causes and consequences of microRNA dysregulation in cancer

28 July 2018

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Notch signaling in the hematopoietic system

28 July 2018

1 reference

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MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells

28 July 2018

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miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy

28 July 2018

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Efficacy and safety of the combination of docetaxel (Taxotere) with targeted therapies in the treatment of solid malignancies

28 July 2018

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Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells

28 July 2018

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Understanding the causes of multidrug resistance in cancer: a comparison of doxorubicin and sunitinib

28 July 2018

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Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment.

28 July 2018

1 reference

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The fibroblast growth factor receptor signaling pathway as a mediator of intrinsic resistance to EGFR-specific tyrosine kinase inhibitors in non-small cell lung cancer

28 July 2018

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The miR-34 family in cancer and apoptosis

28 July 2018

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Notch signaling: the core pathway and its posttranslational regulation

28 July 2018

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MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents

28 July 2018

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The canonical Notch signaling pathway: unfolding the activation mechanism

28 July 2018

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Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression

28 July 2018

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Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic

28 July 2018

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Exploitation of the Notch signaling pathway as a novel target for cancer therapy.

28 July 2018

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gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity

28 July 2018

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Emerging role of Notch in stem cells and cancer

28 July 2018

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Gamma-secretase inhibition combined with platinum compounds enhances cell death in a large subset of colorectal cancer cells

28 July 2018

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Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres

28 July 2018

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Rational targeting of Notch signaling in cancer

28 July 2018

1 reference

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Notch tumor suppressor function

28 July 2018

1 reference

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Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers

28 July 2018

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Synergistic effects of multiple natural products in pancreatic cancer cells

28 July 2018

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Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches

28 July 2018

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Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis

28 July 2018

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Identification and characterization of ovarian cancer-initiating cells from primary human tumors

28 July 2018

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Association of low expression of notch-1 and jagged-1 in human papillary bladder cancer and shorter survival

28 July 2018

1 reference

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Role of mTOR in anticancer drug resistance: perspectives for improved drug treatment

28 July 2018

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MicroRNA regulation of cell lineages in mouse and human embryonic stem cells

28 July 2018

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Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations

28 July 2018

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Gamma-secretase inhibitors enhance taxane-induced mitotic arrest and apoptosis in colon cancer cells

28 July 2018

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Effects of recombinant erythropoietin on breast cancer-initiating cells

28 July 2018

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Leukemic stem cells: from metabolic pathways and signaling to a new concept of drug resistance targeting

28 July 2018

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Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy

28 July 2018

1 reference

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JAG1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer

28 July 2018

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Mammary stem cells and breast cancer--role of Notch signalling.

28 July 2018

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Resveratrol-induced apoptosis in human T-cell acute lymphoblastic leukaemia MOLT-4 cells

28 July 2018

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Notch and cancer: a double-edged sword

28 July 2018

1 reference

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Breast cancer expressing the activated HER2/neu is sensitive to gefitinib in vitro and in vivo and acquires resistance through a novel point mutation in the HER2/neu

28 July 2018

1 reference

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Cancer stem cell: target for anti-cancer therapy

28 July 2018

1 reference

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Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells.

28 July 2018

1 reference

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High-level JAG1 mRNA and protein predict poor outcome in breast cancer

28 July 2018

1 reference

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Notch signaling, gamma-secretase inhibitors, and cancer therapy

28 July 2018

1 reference

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Notch signalling: a simple pathway becomes complex

28 July 2018

1 reference

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Epidermal growth factor receptor-related protein inhibits cell growth and invasion in pancreatic cancer

28 July 2018

1 reference

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Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines

28 July 2018

1 reference

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NOTCH signaling as a novel cancer therapeutic target

28 July 2018

1 reference

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Down-regulation of Jagged-1 induces cell growth inhibition and S phase arrest in prostate cancer cells

28 July 2018

1 reference

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Targeting multidrug resistance in cancer

28 July 2018

1 reference

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Complex networks orchestrate epithelial-mesenchymal transitions

28 July 2018

1 reference

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28 July 2018

1 reference

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Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients

28 July 2018

1 reference

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MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling

28 July 2018

1 reference

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The Notch pathway in cancer: differentiation gone awry

28 July 2018

1 reference

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High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

28 July 2018

1 reference

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The love-hate relationship between Ras and Notch.

28 July 2018

1 reference

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Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic

28 July 2018

1 reference

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miRNAs, cancer, and stem cell division

28 July 2018

1 reference

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Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Involvement of Notch-1 signaling in bone marrow stroma-mediated de novo drug resistance of myeloma and other malignant lymphoid cell lines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Notch1 functions as a tumor suppressor in mouse skin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Mechanisms of cancer drug resistance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Stem cells, cancer, and cancer stem cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Arbiter of differentiation and death: Notch signaling meets apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

The Ins and Outs of Notch Signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Notch-1 and notch-4 receptors as prognostic markers in breast cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-kappaB signaling pathways

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Identification of microRNA profiles in docetaxel-resistant human non-small cell lung carcinoma cells (SPC-A1).

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

RUNX3 directly interacts with intracellular domain of Notch1 and suppresses Notch signaling in hepatocellular carcinoma cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Expression of Notch1, Jagged1 and beta-catenin and their clinicopathological significance in hepatocellular carcinoma.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Notch and Kras in pancreatic cancer: at the crossroads of mutation, differentiation and signaling

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Systematic analysis of microRNA involved in resistance of the MCF-7 human breast cancer cell to doxorubicin

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Notch signaling: where pancreatic cancer and differentiation meet?

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Selective ablation of Notch3 in HCC enhances doxorubicin's death promoting effect by a p53 dependent mechanism

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Tumor-initiating cells of HER2-positive carcinoma cell lines express the highest oncoprotein levels and are sensitive to trastuzumab

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Cross-talk between Notch and EGFR signaling in human breast cancer cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Activity of lapatinib a novel HER2 and EGFR dual kinase inhibitor in human endometrial cancer cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Development and characterization of gemcitabine-resistant pancreatic tumor cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Notch signaling in T-cell acute lymphoblastic leukemia

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Down-regulation of Notch-1 contributes to cell growth inhibition and apoptosis in pancreatic cancer cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Inhibition of nuclear factor kappab activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Notch signaling from tumor cells: a new mechanism of angiogenesis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Nuclear betaII-tubulin associates with the activated notch receptor to modulate notch signaling

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

JAGGED1 expression is associated with prostate cancer metastasis and recurrence

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Down-regulation of Platelet-Derived Growth Factor-D Inhibits Cell Growth and Angiogenesis through Inactivation of Notch-1 and Nuclear Factor-κB Signaling

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955995

Off the beaten pathway: the complex cross talk between Notch and NF-kappaB

28 October 2018

1 reference

12 December 2020

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells

1 reference

12 December 2020

Mechanisms of tumor resistance to EGFR-targeted therapies

1 reference

12 December 2020

Correlation of Notch1 expression and activation to cisplatin-sensitivity of head and neck squamous cell carcinoma

1 reference

12 December 2020

Expression of Stat3 and Notch1 is associated with cisplatin resistance in head and neck squamous cell carcinoma

1 reference

12 December 2020

ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor

1 reference

12 December 2020

Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells

1 reference

12 December 2020

10.1016/J.BBCAN.2010.06.001

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20600632%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20600632%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

20600632

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20600632%20AND%20SRC:MED&resulttype=core&format=json