NVP-BEZ-235 enhances radiosensitization via blockade of the PI3K/mTOR pathway in cisplatin-resistant non-small cell lung carcinoma (Q34170552)

25221647

31 July 2017

title

NVP-BEZ-235 enhances radiosensitization via blockade of the PI3K/mTOR pathway in cisplatin-resistant non-small cell lung carcinoma (English)

1 reference

31 July 2017

1 reference

Kwang Woon Kim

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221647%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Carey J Myers

series ordinal

1 reference

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31 May 2020

Dae Kwang Jung

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221647%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Bo Lu

series ordinal

1 reference

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31 May 2020

language of work or name

1 reference

1 July 2014

1 reference

31 July 2017

1 reference

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31 May 2020

volume

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31 May 2020

issue

7-8

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31 May 2020

page(s)

293-302

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Autophagy and ionizing radiation in tumors: the "survive or not survive" dilemma

31 May 2020

cites work

1 reference

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Aldehyde Dehydrogenase Activity of Breast Cancer Stem Cells Is Primarily Due To Isoform ALDH1A3 and Its Expression Is Predictive of Metastasis

5 July 2018

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The efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 compared with rapamycin in renal cell carcinoma

5 July 2018

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Antitumor efficacy profile of PKI-402, a dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor

5 July 2018

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Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/mTOR-addicted lymphomas

5 July 2018

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Dual phosphoinositide 3-kinase/mammalian target of rapamycin blockade is an effective radiosensitizing strategy for the treatment of non-small cell lung cancer harboring K-RAS mutations

5 July 2018

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NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas

5 July 2018

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5 July 2018

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Emerging therapeutic targets in non-small cell lung cancer

5 July 2018

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Activity of a novel, dual PI3-kinase/mTor inhibitor NVP-BEZ235 against primary human pancreatic cancers grown as orthotopic xenografts.

5 July 2018

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Radiation-induced autophagy in normal and cancer cells: towards novel cytoprotection and radio-sensitization policies?

5 July 2018

1 reference

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NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162139

Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

5 July 2018

1 reference

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Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy

5 July 2018

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Targeting phosphoinositide 3-kinase: moving towards therapy

5 July 2018

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PTEN inactivation in lung cancer cells and the effect of its recovery on treatment with epidermal growth factor receptor tyrosine kinase inhibitors.

5 July 2018

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Targeting mTOR signaling in lung cancer

5 July 2018

1 reference

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Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling.

5 July 2018

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The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

5 July 2018

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Ras, PI(3)K and mTOR signalling controls tumour cell growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162139

Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162139

The role of autophagy in cancer development and response to therapy.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162139

High frequency of mutations of the PIK3CA gene in human cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162139

Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162139

Genomic copy number analysis of non-small cell lung cancer using array comparative genomic hybridization: implications of the phosphatidylinositol 3-kinase pathway

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4162139

DNA gains in 3q occur frequently in squamous cell carcinoma of the lung, but not in adenocarcinoma

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25221647

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/GENESANDCANCER.27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221647%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25221647%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

25221647

1 reference

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