Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGFβ activation (Q34163525)

31 July 2017

title

Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGFβ activation (English)

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31 July 2017

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Shanna A Arnold

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31 July 2017

Lee B Rivera

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31 July 2017

Juliet G Carbon

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31 July 2017

Jason E Toombs

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31 July 2017

Chi-Lun Chang

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31 July 2017

Amy D Bradshaw

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31 July 2017

Rolf A Brekken

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31 July 2017

language of work or name

English

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publication date

14 February 2012

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31 July 2017

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

e31384

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Creative Commons Attribution 4.0 International

31 July 2017

start time

14 February 2012

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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5 July 2018

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5 July 2018

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Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice

5 July 2018

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Decorin core protein fragment Leu155-Val260 interacts with TGF-beta but does not compete for decorin binding to type I collagen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279359

Modulation of SPARC expression during butyrate-induced terminal differentiation of cultured human keratinocytes: regulation via a TGF-beta-dependent pathway

5 July 2018

1 reference

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Differential expression of SPARC and thrombospondin 1 in wound repair: immunolocalization and in situ hybridization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279359

Bone matrix decorin binds transforming growth factor-beta and enhances its bioactivity

5 July 2018

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Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood brain barrier

5 July 2018

1 reference

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Regulation of the expression of a secreted acidic protein rich in cysteine (SPARC) in human fibroblasts by transforming growth factor beta. Comparison of transcriptional and post-transcriptional control with fibronectin and type I collagen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279359

The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279359

SPARC/osteonectin mRNA is induced in blood vessels following injury to the adult rat cerebral cortex

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031384

SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031384

SPARC (BM-40, osteonectin) inhibits the mitogenic effect of vascular endothelial growth factor on microvascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031384

SPARC regulates TGF-beta1-dependent signaling in primary glomerular mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031384

Add-on angiotensin II receptor blockade lowers urinary transforming growth factor-beta levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031384

Thrombospondin 1 mediates angiotensin II induction of TGF-beta activation by cardiac and renal cells under both high and low glucose conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031384

Angiotensin II stimulates migration of retinal microvascular pericytes: involvement of TGF-beta and PDGF-BB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031384

Optimization of a dihydropyrrolopyrazole series of transforming growth factor-beta type I receptor kinase domain inhibitors: discovery of an orally bioavailable transforming growth factor-beta receptor type I inhibitor as antitumor agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031384

Alterations in the lens capsule contribute to cataractogenesis in SPARC-null mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279359

SPARC deficiency leads to early-onset cataractogenesis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279359

Angiotensin II induces thrombospondin-1 production in human mesangial cells via p38 MAPK and JNK: a mechanism for activation of latent TGF-β1

28 October 2018

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12 December 2020

Monoclonal antibodies recognizing transforming growth factor-beta. Bioactivity neutralization and transforming growth factor beta 2 affinity purification

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12 December 2020

SPARC antagonizes the effect of basic fibroblast growth factor on the migration of bovine aortic endothelial cells

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12 December 2020

TGF-beta 1 induces the expression of type I collagen and SPARC, and enhances contraction of collagen gels, by fibroblasts from young and aged donors

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12 December 2020

Selective inactivity of TGF-beta/decorin complexes

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12 December 2020

The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host

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12 December 2020

Transforming growth factor beta in hypertensives with cardiorenal damage

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12 December 2020

Cell-matrix interactions: the view from the outside

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12 December 2020

SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions

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12 December 2020

The synergistic effect of TGF-beta and 1,25-dihydroxyvitamin D3 on SPARC synthesis and alkaline phosphatase activity in human pulp fibroblasts

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0031384

Identifiers

DOI

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31 July 2017

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31 July 2017

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