Regulatory T cells and immune tolerance to tumors (Q37599669)

21 August 2017

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title

Regulatory T cells and immune tolerance to tumors (English)

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21 August 2017

Xuefang Cao

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21 August 2017

publication date

1 March 2010

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21 August 2017

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21 August 2017

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21 August 2017

issue

1-3

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21 August 2017

page(s)

79-93

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CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

21 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS12026-009-8124-7

IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8124-7

Tolerogenic treatment of lupus mice with consensus peptide induces Foxp3-expressing, apoptosis-resistant, TGFbeta-secreting CD8+ T cell suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8124-7

Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8124-7

Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-beta and FOXP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8124-7

In vitro and in vivo down-regulation of regulatory T cell activity with a peptide inhibitor of TGF-beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8124-7

Human CD4+ CD25+ Foxp3+ regulatory T cells do not constitutively express IL-35.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8124-7

Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8124-7

Transplantation survival is maintained by granzyme B+ regulatory cells and adaptive regulatory T cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12026-009-8124-7

Human circulating CD4+CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-009-8124-7

Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance

21 January 2018

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12 December 2020

Tregs and rethinking cancer immunotherapy

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12 December 2020

In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer

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12 December 2020

Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo

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12 December 2020

A critical function for type I interferons in cancer immunoediting

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12 December 2020

Interferons, immunity and cancer immunoediting

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12 December 2020

Donor lymphocyte infusion induces long-term donor-specific cardiac xenograft survival through activation of recipient double-negative regulatory T cells

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12 December 2020

Cytotoxic T lymphocyte antigen-4-dependent down-modulation of costimulatory molecules on dendritic cells in CD4+ CD25+ regulatory T-cell-mediated suppression

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12 December 2020

Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation

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12 December 2020

Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity

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12 December 2020

Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway

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12 December 2020

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

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12 December 2020

IDO expression by dendritic cells: tolerance and tryptophan catabolism

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12 December 2020

Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression

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12 December 2020

Immunoregulatory pathways controlling progression of autoimmunity in NOD mice

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12 December 2020

Accelerated chemically induced tumor development mediated by CD4+CD25+ regulatory T cells in wild-type hosts

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12 December 2020

Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells

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12 December 2020

Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance.

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12 December 2020

Interleukin-10-deficient mice develop chronic enterocolitis

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12 December 2020

TCR vaccines for active immunotherapy of T cell malignancies

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12 December 2020

Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome.

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12 December 2020

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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12 December 2020

Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells

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12 December 2020

CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner

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12 December 2020

Regulation of cutaneous malignancy by gammadelta T cells

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12 December 2020

Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma

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12 December 2020

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

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12 December 2020

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

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12 December 2020

In vivo natural killer cell activities revealed by natural killer cell-deficient mice

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12 December 2020

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

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12 December 2020

NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma.

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12 December 2020

Plasmacytoid dendritic cells induce CD8+ regulatory T cells in human ovarian carcinoma.

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12 December 2020

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

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12 December 2020

Involvement of cellular death in TRAIL/DR5-dependent suppression induced by CD4(+)CD25(+) regulatory T cells

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12 December 2020

Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice

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12 December 2020

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

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12 December 2020

Does the immune system see tumors as foreign or self?

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12 December 2020

The development and function of regulatory T cells

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12 December 2020

The immunobiology of cancer immunosurveillance and immunoediting

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12 December 2020

Human T regulatory cells can use the perforin pathway to cause autologous target cell death

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12 December 2020

How regulatory T cells work

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12 December 2020

Optimizing denileukin diftitox (Ontak) therapy

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12 December 2020

Inhibition of T cell proliferation by macrophage tryptophan catabolism

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12 December 2020

Differential tumor surveillance by natural killer (NK) and NKT cells.

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12 December 2020

CTLA-4 control over Foxp3+ regulatory T cell function

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12 December 2020

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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12 December 2020

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

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12 December 2020

Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines

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12 December 2020

Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes

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12 December 2020

Regulatory T cells in immune surveillance and treatment of cancer.

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12 December 2020

Lymphocyte-mediated cytotoxicity.

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12 December 2020

Immune therapy for cancer

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12 December 2020

Regulatory T cells dynamically control the primary immune response to foreign antigen

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12 December 2020

Overcoming immunologic tolerance to melanoma: targeting CTLA-4 with ipilimumab (MDX-010).

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12 December 2020

Activated CD4+CD25+ T cells selectively kill B lymphocytes

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12 December 2020

Isolation and characterization of human antigen-specific TCR alpha beta+ CD4(-)CD8- double-negative regulatory T cells

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12 December 2020

Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity

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12 December 2020

T cell apoptosis by tryptophan catabolism

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12 December 2020

Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis

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12 December 2020

Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

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12 December 2020

Regulatory T cells, tumour immunity and immunotherapy

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12 December 2020

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

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12 December 2020

A function for interleukin 2 in Foxp3-expressing regulatory T cells

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12 December 2020

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

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12 December 2020

In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

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12 December 2020

Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

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12 December 2020

Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors

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12 December 2020

Mechanisms of suppression by suppressor T cells

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12 December 2020

A two-step process for thymic regulatory T cell development.

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12 December 2020

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

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12 December 2020

Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

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12 December 2020

Regulatory T cells and immune tolerance

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12 December 2020

An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

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12 December 2020

CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer

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12 December 2020

The expanding universe of regulatory T cell subsets in cancer

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12 December 2020

Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody.

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12 December 2020

In vivo instruction of suppressor commitment in naive T cells

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12 December 2020

Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

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12 December 2020

Immunosuppressive strategies that are mediated by tumor cells

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12 December 2020

Inhibitory MHC class I receptors on NK cells and T cells

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12 December 2020

Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes

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12 December 2020

IL-10 controls ultraviolet-induced carcinogenesis in mice

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12 December 2020

CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells

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12 December 2020

IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

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12 December 2020

Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo

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12 December 2020

The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

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12 December 2020

Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis

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12 December 2020

The IL-4 receptor alpha-chain-binding cytokines, IL-4 and IL-13, induce forkhead box P3-expressing CD25+CD4+ regulatory T cells from CD25-CD4+ precursors

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12 December 2020

CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms

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12 December 2020

The HLA crossroad in tumor immunology

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12 December 2020

Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment

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12 December 2020

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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12 December 2020

Killer cell inhibitory receptors for MHC class I molecules regulate lysis of melanoma cells mediated by NK cells, gamma delta T cells, and antigen-specific CTL.

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12 December 2020

Antigen-processing machinery breakdown and tumor growth

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12 December 2020

A unique subset of CD4+CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment

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12 December 2020

Activation requirements for the induction of CD4+CD25+ T cell suppressor function

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12 December 2020

10.1007/S12026-009-8124-7

Identifiers

DOI

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21 August 2017

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