Molecular Differences and Similarities Between Alzheimer's Disease and the 5XFAD Transgenic Mouse Model of Amyloidosis (Q34132850)

31 July 2017

title

Molecular Differences and Similarities Between Alzheimer's Disease and the 5XFAD Transgenic Mouse Model of Amyloidosis (English)

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31 July 2017

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Thomas G Beach

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31 July 2017

Chera L Maarouf

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31 July 2017

Tyler A Kokjohn

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31 July 2017

Charisse M Whiteside

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31 July 2017

MiMi P Macias

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31 July 2017

Walter M Kalback

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31 July 2017

Marwan N Sabbagh

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31 July 2017

Robert Vassar

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31 July 2017

Alex E Roher

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31 July 2017

publication date

21 November 2013

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31 July 2017

published in

Biochemistry insights

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31 July 2017

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31 July 2017

page(s)

1-10

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Turnover of amyloid precursor protein family members determines their nuclear signaling capability

31 July 2017

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis

5 July 2018

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Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model

5 July 2018

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The intracellular domain of amyloid precursor protein induces neuron-specific apoptosis

5 July 2018

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5 July 2018

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Alzheimer's disease sends the wrong signals--a perspective

5 July 2018

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5 July 2018

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BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins

5 July 2018

1 reference

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Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription

5 July 2018

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5 July 2018

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Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease

5 July 2018

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5 July 2018

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5 July 2018

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Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

5 July 2018

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5 July 2018

1 reference

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Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition

5 July 2018

1 reference

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Amyloid deposition as the central event in the aetiology of Alzheimer's disease

5 July 2018

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Evidence for early cognitive impairment related to frontal cortex in the 5XFAD mouse model of Alzheimer's disease.

5 July 2018

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Detection of APP Intracellular Domain in Brain Tissue

28 October 2018

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Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease

28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.

28 October 2018

1 reference

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Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154482

Caspase cleavage of members of the amyloid precursor family of proteins

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154482

The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154482

The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154482

Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4154482

Protease nexin-2/amyloid beta-protein precursor inhibits factor Xa in the prothrombinase complex

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25210460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4137/BCI.S13025

1 reference

31 July 2017

1 reference

31 July 2017

1 reference