NF-κB, an active player in human cancers (Q34138728)

31 July 2017

title

NF-κB, an active player in human cancers (English)

1 reference

31 July 2017

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Yifeng Xia

1 reference

31 July 2017

Shen Shen

series ordinal

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31 July 2017

Inder M Verma

series ordinal

1 reference

31 July 2017

publication date

1 September 2014

1 reference

Cancer Immunology Research

31 July 2017

published in

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

823-830

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Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms

31 July 2017

cites work

1 reference

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GSK-3α promotes oncogenic KRAS function in pancreatic cancer via TAK1-TAB stabilization and regulation of noncanonical NF-κB.

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TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers.

5 July 2018

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Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model

5 July 2018

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KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.

5 July 2018

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Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1

5 July 2018

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NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration

5 July 2018

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Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma

5 July 2018

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5 July 2018

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NFKBIADeletion in Glioblastomas

5 July 2018

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5 July 2018

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5 July 2018

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Requirement of the NF-kappaB subunit p65/RelA for K-Ras-induced lung tumorigenesis

5 July 2018

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Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation

5 July 2018

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An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

5 July 2018

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Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

5 July 2018

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Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma

5 July 2018

1 reference

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Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB.

5 July 2018

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5 July 2018

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Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion

5 July 2018

1 reference

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Metastasis: from dissemination to organ-specific colonization

5 July 2018

1 reference

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Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-N-acetyl glucosamine modification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Myeloid-derived suppressor cells as regulators of the immune system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Phosphorylation of p53 by IkappaB kinase 2 promotes its degradation by beta-TrCP.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

"Re-educating" tumor-associated macrophages by targeting NF-kappaB.

5 July 2018

1 reference

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Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators

5 July 2018

1 reference

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The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis

5 July 2018

1 reference

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NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta

5 July 2018

1 reference

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Integrative genomic approaches identify IKBKE as a breast cancer oncogene

5 July 2018

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Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB

5 July 2018

1 reference

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Patterns of somatic mutation in human cancer genomes

5 July 2018

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Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis

5 July 2018

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Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models.

5 July 2018

1 reference

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RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Deregulated NF-kappaB activity in haematological malignancies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Epithelial-mesenchymal transitions: twist in development and metastasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

The c-Rel transcription factor and B-cell proliferation: a deal with the devil

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

NF-kappaB regulation in the immune system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

p53 recruitment of CREB binding protein mediated through phosphorylated CREB: a novel pathway of tumor suppressor regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Transcriptional cross talk between NF-kappaB and p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signaling

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Ferritin Heavy Chain Upregulation by NF-κB Inhibits TNFα-Induced Apoptosis by Suppressing Reactive Oxygen Species

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155602

Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25187272

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25187272

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25187272

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/2326-6066.CIR-14-0112

1 reference

31 July 2017

1 reference

31 July 2017

1 reference