Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule (Q24291640)

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10 November 2019

title

Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule (English)

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10 November 2019

0 references

1 reference

GOA release 2020-03-11

MHC class II protein binding

1 reference

GOA release 2020-03-11

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10 November 2019

A Joachimiak

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10 November 2019

J H Wang

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10 November 2019

Y Xiong

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10 November 2019

J H Liu

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10 November 2019

T Sakihama

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10 November 2019

R Zhang

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10 November 2019

E L Reinherz

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10 November 2019

language of work or name

English

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publication date

4 September 2001

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Proceedings of the National Academy of Sciences of the United States of America

10 November 2019

published in

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10 November 2019

volume

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10 November 2019

issue

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10 November 2019

page(s)

10799-10804

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Energetics of the HIV gp120-CD4 binding reaction

10 November 2019

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19 March 2017

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Dimeric association and segmental variability in the structure of human CD4

19 March 2017

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Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1

19 March 2017

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The crystal structure of a T cell receptor in complex with peptide and MHC class II

19 March 2017

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Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical

19 March 2017

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Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb

19 March 2017

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

19 March 2017

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Crystal structure of I-Ak in complex with a dominant epitope of lysozyme

19 March 2017

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Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2

19 March 2017

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Crystal structure of ICAM-2 reveals a distinctive integrin recognition surface

19 March 2017

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Crystal structure of domains 3 and 4 of rat CD4: relation to the NH2-terminal domains

19 March 2017

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19 March 2017

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19 March 2017

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Efficient anisotropic refinement of macromolecular structures using FFT

22 April 2017

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Rapid automated molecular replacement by evolutionary search

19 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

19 March 2017

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19 March 2017

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HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4

22 April 2017

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Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding

19 March 2017

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T cell receptor-MHC interactions up close

19 March 2017

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Structural basis of cell-cell interactions in the immune system

27 September 2017

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Structural basis of T cell recognition

27 September 2017

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One of the CD3epsilon subunits within a T cell receptor complex lies in close proximity to the Cbeta FG loop

27 September 2017

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Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4.

27 September 2017

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Delineation of an extended surface contact area on human CD4 involved in class II major histocompatibility complex binding

27 September 2017

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Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.

27 September 2017

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The T cell antigen receptor alpha and beta chains interact via distinct regions with CD3 chains

27 September 2017

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Involvement of both major histocompatibility complex class II alpha and beta chains in CD4 function indicates a role for ordered oligomerization in T cell activation

27 September 2017

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Oligomerization of CD4 is required for stable binding to class II major histocompatibility complex proteins but not for interaction with human immunodeficiency virus gp120

27 September 2017

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Absence of the Lyt-2-,L3T4+ lineage of T cells in mice treated neonatally with anti-I-A correlates with absence of intrathymic I-A-bearing antigen-presenting cell function

27 September 2017

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27 September 2017

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Equivalence of human and mouse CD4 in enhancing antigen responses by a mouse class II-restricted T cell hybridoma

27 September 2017

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Crystal structure of an HIV-binding recombinant fragment of human CD4.

27 September 2017

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Mutations in the D strand of the human CD4 V1 domain affect CD4 interactions with the human immunodeficiency virus envelope glycoprotein gp120 and HLA class II antigens similarly

27 September 2017

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Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains

27 September 2017

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MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8

27 September 2017

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The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation

27 September 2017

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Human immunodeficiency virus gp120 binding C'C" ridge of CD4 domain 1 is also involved in interaction with class II major histocompatibility complex molecules

27 September 2017

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Human CD4 restores normal T cell development and function in mice deficient in murine CD4.

27 September 2017

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Membrane compartmentation is required for efficient T cell activation.

27 September 2017

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A kinase-independent function of Lck in potentiating antigen-specific T cell activation

30 May 2018

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Species-specific binding of CD4 to the beta 2 domain of major histocompatibility complex class II molecules

30 May 2018

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T Cell Receptor Binding to a pMHCII Ligand Is Kinetically Distinct from and Independent of CD4.

30 May 2018

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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AMoRe: an automated package for molecular replacement

21 January 2018

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

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Modified Phased Translation Functions and their Application to Molecular-Fragment Location

21 January 2018

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Human CD4 residue Phe 43 is critical for repertoire development and maturation of MHC class II restricted CD4 single-positive T lineage cells in vivo

21 January 2018

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Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp120-binding site

21 January 2018

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21 January 2018

Identifiers

DOI

10.1073/PNAS.191124098

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11535811%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11535811%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

11535811

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11535811%20AND%20SRC:MED&resulttype=core&format=json