Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H. (Q34108782)

31 July 2017

title

Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H. (English)

1 reference

31 July 2017

Barry R O'Keefe

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31 July 2017

Suhman Chung

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31 July 2017

Michaela Wendeler

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31 July 2017

Jason W Rausch

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31 July 2017

Greg Beilhartz

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31 July 2017

Matthias Gotte

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31 July 2017

Alun Bermingham

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31 July 2017

John A Beutler

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31 July 2017

Shixin Liu

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31 July 2017

Xiaowei Zhuang

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31 July 2017

Stuart F J Le Grice

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31 July 2017

language of work or name

English

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publication date

14 June 2010

1 reference

Antimicrobial Agents and Chemotherapy

31 July 2017

published in

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

3913-3921

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RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information

31 July 2017

cites work

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Mutations in the thumb allow human immunodeficiency virus type 1 reverse transcriptase to be cleaved by protease in virions

5 July 2018

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HIV-1 reverse transcriptase can simultaneously engage its DNA/RNA substrate at both DNA polymerase and RNase H active sites: implications for RNase H inhibition

5 July 2018

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5 July 2018

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Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity

5 July 2018

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HIV-1 ribonuclease H inhibitory phenolic glycosides from Eugenia hyemalis

5 July 2018

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5 July 2018

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5 July 2018

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Dynamic binding orientations direct activity of HIV reverse transcriptase

5 July 2018

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5 July 2018

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HIV-1 Reverse Transcriptase Structure with RNase H Inhibitor Dihydroxy Benzoyl Naphthyl Hydrazone Bound at a Novel Site

5 July 2018

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Indolopyridones inhibit human immunodeficiency virus reverse transcriptase with a novel mechanism of action

5 July 2018

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Structure-activity relationships of [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]- 3'-spiro-5' '-(4' '-amino-1' ',2' '-oxathiole-2' ',2' '-dioxide)thymine derivatives as inhibitors of HIV-1 reverse transcriptase dimerization.

5 July 2018

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Recent progress in the design of small molecule inhibitors of HIV RNase H.

5 July 2018

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Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones

5 July 2018

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5 July 2018

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Two-metal ion mechanism of RNA cleavage by HIV RNase H and mechanism-based design of selective HIV RNase H inhibitors

5 July 2018

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Inhibition of HIV-1 ribonuclease H by a novel diketo acid, 4-[5-(benzoylamino)thien-2-yl]-2,4-dioxobutanoic acid

5 July 2018

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Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA

5 July 2018

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5 July 2018

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

5 July 2018

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Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone

5 July 2018

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A novel neutralization epitope on the 'thumb' subdomain of human immunodeficiency virus type 1 reverse transcriptase revealed by a monoclonal antibody

5 July 2018

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Significant discrepancies between van't Hoff and calorimetric enthalpies

5 July 2018

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The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1

5 July 2018

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Complete nucleotide sequences of functional clones of the AIDS virus

5 July 2018

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New soluble-formazan assay for HIV-1 cytopathic effects: application to high-flux screening of synthetic and natural products for AIDS-antiviral activity

5 July 2018

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Point mutations in conserved amino acid residues within the C-terminal domain of HIV-1 reverse transcriptase specifically repress RNase H function

5 July 2018

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Subunit-selective mutagenesis indicates minimal polymerase activity in heterodimer-associated p51 HIV-1 reverse transcriptase

5 July 2018

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Mutations within the RNase H Domain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Abolish Virus Infectivity

5 July 2018

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An HIV RNase H inhibitory 1,3,4,5-tetragalloylapiitol from the African plant Hylodendron gabunensis

5 July 2018

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Van't Hoff and calorimetric enthalpies from isothermal titration calorimetry: are there significant discrepancies?

28 October 2018

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Structure/function studies of human immunodeficiency virus type 1 reverse transcriptase. Alanine scanning mutagenesis of an alpha-helix in the thumb subdomain

28 October 2018

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A dimeric lactone from Ardisia japonica with inhibitory activity for HIV-1 and HIV-2 ribonuclease H

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20547794

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.00434-10

1 reference

31 July 2017

1 reference

31 July 2017

1 reference