Epigenetic GABAergic targets in schizophrenia and bipolar disorder (Q34087810)

30 July 2017

title

Epigenetic GABAergic targets in schizophrenia and bipolar disorder (English)

1 reference

30 July 2017

0 references

1 reference

A. Guidotti

1 reference

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J. Auta

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26 August 2024

Y. Chen

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J. M. Davis

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E. Dong

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D. P. Gavin

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D. R. Grayson

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F. Matrisciano

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R. Satta

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R. P. Sharma

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L. Tremolizzo

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P. Tueting

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26 August 2024

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21074545

26 August 2024

publication date

11 November 2010

1 reference

full work available at URL

30 July 2017

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inferred from page(s)

https://europepmc.org/articles/pmc4144274?pdf=render

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21074545

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21074545/pdf/?tool=EBI

26 August 2024

1 reference

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21074545/?tool=EBI

26 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21074545

https://europepmc.org/articles/PMC4144274

26 August 2024

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26 August 2024

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https://doi.org/10.1016/j.neuropharm.2010.10.021

26 August 2024

online access status

open access

1 reference

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https://api.elsevier.com/content/article/PII:S0028390810002911?httpAccept=text/xml

26 August 2024

1 reference

10.1016/J.NEUROPHARM.2010.10.021

Crossref

DOI

https://api.crossref.org/works/10.1016/J.NEUROPHARM.2010.10.021

https://api.elsevier.com/content/article/PII:S0028390810002911?httpAccept=text/plain

26 August 2024

1 reference

10.1016/J.NEUROPHARM.2010.10.021

Crossref

DOI

https://api.crossref.org/works/10.1016/J.NEUROPHARM.2010.10.021

26 August 2024

1 reference

30 July 2017

1 reference

30 July 2017

issue

7-8

1 reference

30 July 2017

page(s)

1007-1016

1 reference

Analysis of the GAD1 promoter: Trans-acting factors and DNA methylation converge on the 5′ untranslated region

30 July 2017

cites work

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Altered histone acetylation is associated with age-dependent memory impairment in mice.

28 July 2018

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L-methionine decreases dendritic spine density in mouse frontal cortex

28 July 2018

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Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes

28 July 2018

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28 July 2018

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28 July 2018

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Active DNA demethylation mediated by DNA glycosylases

28 July 2018

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Epigenetic mechanisms in schizophrenia

28 July 2018

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An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes.

28 July 2018

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Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis

28 July 2018

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Divalproex ER combined with olanzapine or risperidone for treatment of acute exacerbations of schizophrenia

28 July 2018

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The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes

28 July 2018

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Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons

28 July 2018

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N-methyl-D-aspartate receptor and calbindin-containing neurons in the anterior cingulate cortex in schizophrenia and bipolar disorder

28 July 2018

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The colorful history of active DNA demethylation.

28 July 2018

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Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia

28 July 2018

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Genomewide association for schizophrenia in the CATIE study: results of stage 1

28 July 2018

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Epigenomic profiling reveals DNA-methylation changes associated with major psychosis

28 July 2018

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Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women

28 July 2018

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The role of reelin in adult synaptic function and the genetic and epigenetic regulation of the reelin gene

28 July 2018

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Reviewing the role of DNA (cytosine-5) methyltransferase overexpression in the cortical GABAergic dysfunction associated with psychosis vulnerability

28 July 2018

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Histone deactylase 1 expression is increased in the prefrontal cortex of schizophrenia subjects: analysis of the National Brain Databank microarray collection

28 July 2018

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Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters

28 July 2018

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Epigenetics and complex disease: from etiology to new therapeutics

28 July 2018

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Neuroplasticity of neocortical circuits in schizophrenia.

28 July 2018

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Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families

28 July 2018

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The pipeline and future of drug development in schizophrenia.

28 July 2018

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Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars

28 July 2018

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Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters

28 July 2018

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Covalent modification of DNA regulates memory formation

28 July 2018

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Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder

28 July 2018

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Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection.

28 July 2018

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S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis

28 July 2018

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Schizophrenia: new pathological insights and therapies

28 July 2018

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The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia.

28 July 2018

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Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood

28 July 2018

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The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases.

28 July 2018

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Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia

28 July 2018

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Reelin promoter hypermethylation in schizophrenia

28 July 2018

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DNA methylation and demethylation as targets for anticancer therapy

28 July 2018

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GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon.

28 July 2018

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Histone deacetylase inhibitors decrease reelin promoter methylation in vitro

28 July 2018

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Cortical inhibitory neurons and schizophrenia

28 July 2018

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Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice

28 July 2018

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Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report

28 July 2018

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DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures

28 July 2018

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Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder

28 July 2018

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Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration.

28 July 2018

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Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia

28 July 2018

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REELIN and schizophrenia: a disease at the interface of the genome and the epigenome

28 July 2018

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Bringing order to the glutamate chaos in schizophrenia

28 July 2018

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Valproate induces replication-independent active DNA demethylation

28 July 2018

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An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability

28 July 2018

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Dendritic spine hypoplasticity and downregulation of reelin and GABAergic tone in schizophrenia vulnerability.

28 July 2018

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Translating the Histone Code

28 July 2018

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GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder

28 July 2018

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Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression

28 July 2018

1 reference

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Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study

28 July 2018

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Randomized, placebo-controlled pilot study of divalproex sodium in the treatment of acute exacerbations of chronic schizophrenia

28 July 2018

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A decrease of reelin expression as a putative vulnerability factor in schizophrenia

28 July 2018

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Neurotrophin regulation of cortical dendritic growth requires activity

28 July 2018

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DNA methylation in early development

28 July 2018

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Increased GABAA receptor binding in superficial layers of cingulate cortex in schizophrenics

28 July 2018

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Grand challenges and opportunities for molecular psychiatry research: A perspective

28 July 2018

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Valproate induces DNA demethylation in nuclear extracts from adult mouse brain

28 October 2018

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Is pharma running out of brainy ideas?

28 October 2018

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Reelin regulates postnatal neurogenesis and enhances spine hypertrophy and long-term potentiation

28 October 2018

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Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling

28 October 2018

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Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation

28 October 2018

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Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs

28 October 2018

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Adjunct divalproex or lithium to clozapine in treatment-resistant schizophrenia

28 October 2018

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Analysis of pyramidal neuron morphology in an inducible knockout of brain-derived neurotrophic factor

28 October 2018

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Clozapine and the mitogen-activated protein kinase signal transduction pathway: implications for antipsychotic actions

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144274

In psychosis, cortical interneurons overexpress DNA-methyltransferase 1

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144274

Decreased expression of vesicular glutamate transporter 1 and complexin II mRNAs in schizophrenia: further evidence for a synaptic pathology affecting glutamate neurons

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144274

Regulation of histone acetylation during memory formation in the hippocampus.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144274

GAD67 and GAD65 mRNA and protein expression in cerebrocortical regions of elderly patients with schizophrenia

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144274

DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144274

Abnormal regulation of high affinity nicotinic receptors in subjects with schizophrenia.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144274

The phenotypic characteristics of heterozygous reeler mouse

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144274

Valproate: a reappraisal of its pharmacodynamic properties and mechanisms of action

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144274

Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144274

Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21074545

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Induction of the reelin promoter by retinoic acid is mediated by Sp1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21074545

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NEUROPHARM.2010.10.021

1 reference

30 July 2017

1 reference

30 July 2017

1 reference