Guided delivery of adeno-associated viral vectors into the primate brain (Q34061373)

30 July 2017

title

Guided delivery of adeno-associated viral vectors into the primate brain (English)

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30 July 2017

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Ernesto A Salegio

1 reference

30 July 2017

Lluis Samaranch

1 reference

30 July 2017

Adrian P Kells

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30 July 2017

John Forsayeth

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30 July 2017

Krystof Bankiewicz

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30 July 2017

language of work or name

English

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publication date

20 October 2011

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Advanced Drug Delivery Reviews

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

598-604

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Interventional MRI-guided putaminal delivery of AAV2-GDNF for a planned clinical trial in Parkinson's disease

30 July 2017

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Qualitative imaging of adeno-associated virus serotype 2-human aromatic L-amino acid decarboxylase gene therapy in a phase I study for the treatment of Parkinson disease.

28 July 2018

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Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF.

28 July 2018

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Real-time MR imaging with Gadoteridol predicts distribution of transgenes after convection-enhanced delivery of AAV2 vectors

28 July 2018

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Magnetic resonance imaging-guided delivery of adeno-associated virus type 2 to the primate brain for the treatment of lysosomal storage disorders

28 July 2018

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Image-guided convection-enhanced delivery of GDNF protein into monkey putamen

28 July 2018

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Convection-enhanced delivery of liposomes to primate brain.

28 July 2018

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Safety and tolerability of putaminal AADC gene therapy for Parkinson disease

28 July 2018

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Optimal region of the putamen for image-guided convection-enhanced delivery of therapeutics in human and non-human primates

28 July 2018

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Anatomic compression caused by high-volume convection-enhanced delivery to the brain

28 July 2018

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Safety evaluation of AAV2-GDNF gene transfer into the dopaminergic nigrostriatal pathway in aged and parkinsonian rhesus monkeys

28 July 2018

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Controlled dissemination of AAV vectors in the primate brain

28 July 2018

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Nigrostriatal rAAV-mediated GDNF overexpression induces robust weight loss in a rat model of age-related obesity.

28 July 2018

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Functional effects of AAV2-GDNF on the dopaminergic nigrostriatal pathway in parkinsonian rhesus monkeys

28 July 2018

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Clinically relevant effects of convection-enhanced delivery of AAV2-GDNF on the dopaminergic nigrostriatal pathway in aged rhesus monkeys

28 July 2018

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The thalamocortical projection systems in primate: an anatomical support for multisensory and sensorimotor interplay

28 July 2018

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Real-time MR imaging of adeno-associated viral vector delivery to the primate brain

28 July 2018

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Detection of infusate leakage in the brain using real-time imaging of convection-enhanced delivery.

28 July 2018

1 reference

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The cortico-basal ganglia integrative network: the role of the thalamus

28 July 2018

1 reference

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Striatal volume differences between non-human and human primates

28 July 2018

1 reference

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Biodistribution of adeno-associated virus type-2 in nonhuman primates after convection-enhanced delivery to brain

28 July 2018

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Results from a phase I safety trial of hAADC gene therapy for Parkinson disease

28 July 2018

1 reference

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Image-guided convection-enhanced delivery platform in the treatment of neurological diseases.

28 July 2018

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The thalamus is more than just a relay

28 July 2018

1 reference

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Real-time imaging and quantification of brain delivery of liposomes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

A dose-ranging study of AAV-hAADC therapy in Parkinsonian monkeys

28 July 2018

1 reference

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The "perivascular pump" driven by arterial pulsation is a powerful mechanism for the distribution of therapeutic molecules within the brain

28 July 2018

1 reference

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Focal striatal dopamine may potentiate dyskinesias in parkinsonian monkeys

28 July 2018

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Dimerizer regulation of AADC expression and behavioral response in AAV-transduced 6-OHDA lesioned rats

28 July 2018

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Thalamo-cortical connections of areas 3a and M1 in marmoset monkeys

28 July 2018

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Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach

28 July 2018

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Viewpoint: the core and matrix of thalamic organization

28 July 2018

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Convection-enhanced delivery of macromolecules in the brain

28 July 2018

1 reference

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The specificity of the 'nonspecific' midline and intralaminar thalamic nuclei

28 July 2018

1 reference

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Restricted cortical termination fields of the midline and intralaminar thalamic nuclei in the rat

28 July 2018

1 reference

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The afferent and efferent connections of the nucleus submedius in the rat

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Contralateral projections to the dorsal thalamus from frontal association cortex in the rhesus monkey

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Novel platform for MRI-guided convection-enhanced delivery of therapeutics: preclinical validation in nonhuman primate brain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Cannula placement for effective convection-enhanced delivery in the nonhuman primate thalamus and brainstem: implications for clinical delivery of therapeutics.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Efficient gene therapy-based method for the delivery of therapeutics to primate cortex

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Emerging views of corticothalamic function.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Real-time image-guided direct convective perfusion of intrinsic brainstem lesions. Technical note

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Thalamocortical and the dual pattern of corticothalamic projections of the posterior parietal cortex in macaque monkeys

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Convection-enhanced delivery of adeno-associated virus type 2 (AAV2) into the striatum and transport of AAV2 within monkey brain

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Gadolinium-loaded liposomes allow for real-time magnetic resonance imaging of convection-enhanced delivery in the primate brain

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Real-time visualization and characterization of liposomal delivery into the monkey brain by magnetic resonance imaging

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Neuroimaging in Parkinson's disease

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Distribution of liposomes into brain and rat brain tumor models by convection-enhanced delivery monitored with magnetic resonance imaging

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Regulation of gene expression in adeno-associated virus vectors in the brain

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Functional anatomy of thalamus and basal ganglia

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

Distribution of AAV-TK following intracranial convection-enhanced delivery into rats.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

The thalamus of reptiles and mammals: similarities and differences

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279613

T2 imaging in monitoring of intraparenchymal real-time convection-enhanced delivery

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22036906

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Laminar organization of thalamic projections to the rat neocortex

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22036906

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.ADDR.2011.10.005

1 reference

30 July 2017

1 reference

30 July 2017

1 reference