Parameter adaptations during phenotype transitions in progressive diseases. (Q34059056)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22029623%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Parameter adaptations during phenotype transitions in progressive diseases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22029623%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22029623%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Christian A Tiemann

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22029623%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Joep Vanlier

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22029623%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Peter A J Hilbers

series ordinal

1 reference

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15 January 2020

publication date

26 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22029623%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22029623%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22029623%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

174

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22029623%20AND%20SRC:MED&resulttype=core&format=json

When the human viral infectome and diseasome networks collide: towards a systems biology platform for the aetiology of human diseases.

15 January 2020

cites work

1 reference

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Type 2 diabetes as an inflammatory disease

5 July 2018

1 reference

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Atherosclerosis in CKD: differences from the general population.

5 July 2018

1 reference

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Towards whole-body systems physiology.

5 July 2018

1 reference

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Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice

5 July 2018

1 reference

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Role of triglyceride-rich lipoproteins in diabetic nephropathy

5 July 2018

1 reference

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The liver X receptor: control of cellular lipid homeostasis and beyond Implications for drug design

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

LXR-SREBP-1c-phospholipid transfer protein axis controls very low density lipoprotein (VLDL) particle size

5 July 2018

1 reference

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Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions

5 July 2018

1 reference

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Nutritional systems biology modeling: from molecular mechanisms to physiology

5 July 2018

1 reference

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A systems biology framework for modeling metabolic enzyme inhibition of Mycobacterium tuberculosis

5 July 2018

1 reference

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The smallest chemical reaction system with bistability

5 July 2018

1 reference

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Systems biology and the virtual physiological human

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

High fat feeding induces hepatic fatty acid elongation in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Systems-level interactions between insulin-EGF networks amplify mitogenic signaling.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Reduced insulin-mediated inhibition of VLDL secretion upon pharmacological activation of the liver X receptor in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Systems biology: model based evaluation and comparison of potential explanations for given biological data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Systems biology: parameter estimation for biochemical models

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Effect of plasma triglyceride metabolism on lipid storage in adipose tissue: studies using genetically engineered mouse models

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Metabolic syndrome: from epidemiology to systems biology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

SirT1 gain of function increases energy efficiency and prevents diabetes in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

The contribution of animal models to the study of obesity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Vascular aging: insights from studies on cellular senescence, stem cell aging, and progeroid syndromes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

A compartment model of VEGF distribution in blood, healthy and diseased tissues.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Model-based hypothesis testing of key mechanisms in initial phase of insulin signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Systems biology of persistent infection: tuberculosis as a case study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

ALC: automated reduction of rule-based models

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Network-based global inference of human disease genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Knock out, knock in, knock down--genetically manipulated mice and the Nobel Prize

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Pathology of nonalcoholic fatty liver disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Universally sloppy parameter sensitivities in systems biology models

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Computational prediction of cancer-gene function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Metabolic syndrome and robustness tradeoffs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Bow ties, metabolism and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Gene-selective modulation by a synthetic oxysterol ligand of the liver X receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Hepatic VLDL production in ob/ob mice is not stimulated by massive de novo lipogenesis but is less sensitive to the suppressive effects of insulin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Integration from proteins to organs: the Physiome Project

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Computational systems biology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

The liver X receptor gene team: potential new players in atherosclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Modeling the heart--from genes to cells to the whole organ

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Role of LXRs in control of lipogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Mobilisation of triacylglycerol stores

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

The lipolysis/esterification cycle of hepatic triacylglycerol. Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Extracellular fatty acids are not utilized directly for the synthesis of very-low-density lipoprotein in primary cultures of rat hepatocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production

5 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-174

Multistationarity in the activation of a MAPK: parametrizing the relevant region in parameter space

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-174

The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-174

Raising HDL cholesterol without inducing hepatic steatosis and hypertriglyceridemia by a selective LXR modulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-174

Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-174

Multistability of signal transduction motifs

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3354367

Mathematical modeling and analysis of insulin clearance in vivo

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22029623

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Origin of triacylglycerol moiety of plasma very low density lipoproteins in the rat: structural studies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22029623

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Use of cytosolic triacylglycerol hydrolysis products and of exogenous fatty acid for the synthesis of triacylglycerol secreted by cultured rat hepatocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22029623

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1752-0509-5-174

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22029623%20AND%20SRC:MED&resulttype=core&format=json

journals/bmcsb/TiemannVHR11

15 January 2020

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

Dimensions Publication ID

28 January 2021

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22029623%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

22029623

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22029623%20AND%20SRC:MED&resulttype=core&format=json