gammadeltaTCR ligands and lineage commitment (Q34028534)

30 July 2017

1 reference

title

gammadeltaTCR ligands and lineage commitment (English)

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30 July 2017

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Harald von Boehmer

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30 July 2017

Taras Kreslavsky

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30 July 2017

publication date

5 May 2010

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30 July 2017

published in

Seminars in Immunology

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

214-221

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Ligand recognition during thymic development and gammadelta T cell function specification

30 July 2017

cites work

1 reference

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Inhibitor of DNA binding 3 limits development of murine slam-associated adaptor protein-dependent "innate" gammadelta T cells.

5 July 2018

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Gamma delta T cell receptors confer autonomous responsiveness to the insulin-peptide B:9-23.

5 July 2018

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Alphabeta versus gammadelta lineage choice at the first TCR-controlled checkpoint

5 July 2018

1 reference

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Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3.

5 July 2018

1 reference

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Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent

5 July 2018

1 reference

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TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity

5 July 2018

1 reference

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Mechanisms determining cell membrane expression of different gammadelta TCR chain pairings.

5 July 2018

1 reference

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Id3 restricts the developmental potential of gamma delta lineage during thymopoiesis

5 July 2018

1 reference

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Gammadelta T lymphocyte homeostasis is negatively regulated by beta2-microglobulin

5 July 2018

1 reference

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The transcription factor PLZF directs the effector program of the NKT cell lineage

5 July 2018

1 reference

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The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

5 July 2018

1 reference

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Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma

5 July 2018

1 reference

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An autonomous CDR3delta is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by gammadelta T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Macrophages express multiple ligands for gammadelta TCRs

5 July 2018

1 reference

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T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis.

5 July 2018

1 reference

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Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Lineage diversion of T cell receptor transgenic thymocytes revealed by lineage fate mapping.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

gammadelta T-cell receptors: functional correlations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Gammadelta T cells - innate immune lymphocytes?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Human Vgamma9Vdelta2 T cells: promising new leads for immunotherapy of infections and tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

The E delta enhancer controls the generation of CD4- CD8- alphabetaTCR-expressing T cells that can give rise to different lineages of alphabeta T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Helix-loop-helix proteins and lymphocyte development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

{gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

The fourth way? Harnessing aggressive tendencies in the thymus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Positive selection of dendritic epidermal gammadelta T cell precursors in the fetal thymus determines expression of skin-homing receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Selection of the T-cell repertoire: receptor-controlled checkpoints in T-cell development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Biology of gastrointestinal stromal tumors: KIT mutations and beyond

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Detection of cell surface ligands for the gamma delta TCR using soluble TCRs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Production of a soluble gammadelta T-cell receptor to identify ligands for the murine intestinal intraepithelial gammadelta T cell population

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial gamma delta T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Resident skin-specific gammadelta T cells provide local, nonredundant regulation of cutaneous inflammation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Evidence that gammadelta versus alphabeta T cell fate determination is initiated independently of T cell receptor signaling.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Premature expression of T cell receptor (TCR)alphabeta suppresses TCRgammadelta gene rearrangement but permits development of gammadelta lineage T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Different initiation of pre-TCR and gammadeltaTCR signalling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Self-recognition of CD1 by gamma/delta T cells: implications for innate immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

1998 Warkany lecture: signaling pathways in development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Peripheral T Cell Survival Requires Continual Ligation of the T Cell Receptor to Major Histocompatibility Complex–Encoded Molecules

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Differential requirements for survival and proliferation of CD8 naïve or memory T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Role of different T cell receptors in the development of pre-T cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

The alpha beta T cell receptor can replace the gamma delta receptor in the development of gamma delta lineage cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

CDR3 length in antigen-specific immune receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Analysis and expression of a cloned pre-T cell receptor gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Natural and synthetic non-peptide antigens recognized by human gamma delta T cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

T-cell antigen receptor genes and T-cell recognition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Diversity of murine gamma genes and expression in fetal and adult T lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Recognition of a self major histocompatibility complex TL region product by gamma delta T-cell receptors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Recognition of Self Antigens by Skin-Derived T Cells with Invariant γδ Antigen Receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

The vitronectin receptor serves as an accessory molecule for the activation of a subset of gamma/delta T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Heat shock protein Hsp60-reactive gamma delta cells: a large, diversified T-lymphocyte subset with highly focused specificity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Most gamma delta T cells develop normally in beta 2-microglobulin-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Exclusion and inclusion of α and β T cell receptor alleles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Mouse autoreactive gamma/delta T cells. II. Molecular characterization of the T cell receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Visualization of the earliest steps of gammadelta T cell development in the adult thymus

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

A keratinocyte-responsive gamma delta TCR is necessary for dendritic epidermal T cell activation by damaged keratinocytes and maintenance in the epidermis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Hybridomas expressing gammadelta T-cell receptors respond to cardiolipin and beta2-glycoprotein 1 (apolipoprotein H).

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

The developmental fate of T cells is critically influenced by TCRgammadelta expression.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

A novel subset of adult gamma delta thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted T cell receptor repertoire

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Recognition of the product of a novel MHC TL region gene (27b) by a mouse gamma delta T cell receptor

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Mechanistic basis of pre–T cell receptor–mediated autonomous signaling critical for thymocyte development

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912151

Origins of gammadeltaT cells: a forum for opposing perspectives

29 October 2018

1 reference

12 December 2020

Response of murine gamma delta T cells to the synthetic polypeptide poly-Glu50Tyr50

1 reference

12 December 2020

Failure of HY-Specific Thymocytes to Escape Negative Selection by Receptor Editing

1 reference

12 December 2020

Most IL-4-producing gamma delta thymocytes of adult mice originate from fetal precursors

1 reference

12 December 2020

Rates of recombination and chain pair biases greatly influence the primary gammadelta TCR repertoire in the thymus of adult mice

1 reference

12 December 2020

Stimulation of a major subset of lymphocytes expressing T cell receptor gamma delta by an antigen derived from Mycobacterium tuberculosis

1 reference

12 December 2020

Qa-1 restricted recognition of foreign antigen by a γδ T-cell hybridoma

1 reference

12 December 2020

Structure and specificity of a class II MHC alloreactive gamma delta T cell receptor heterodimer

1 reference

12 December 2020

Limited receptor repertoire in a mycobacteria-reactive subset of γδ T lymphocytes

1 reference

12 December 2020

Extrathymic selection of TCR gamma delta + T cells by class II major histocompatibility complex molecules

1 reference

12 December 2020

Mouse autoreactive gamma/delta T cells. I. Functional properties of autoreactive T cell hybridomas

1 reference

12 December 2020

Gene transfer demonstrates that the V gamma 1.1C gamma 4V delta 6C delta T cell receptor is essential for autoreactivity

1 reference

12 December 2020

Analysis of intraepithelial lymphocytes from major histocompatibility complex (MHC)-deficient mice: no evidence for a role of MHC class II antigens in the positive selection of V delta 4+ gamma delta T cells

1 reference

12 December 2020

Structural requirements for peptides that stimulate a subset of gamma delta T cells

1 reference

12 December 2020

MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

1 reference

12 December 2020

Targeted Complementation of MHC Class II Deficiency by Intrathymic Delivery of Recombinant Adenoviruses

1 reference

12 December 2020

Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I

1 reference

12 December 2020

Antigen recognition determinants of gammadelta T cell receptors

1 reference

12 December 2020

TCR signal strength influences alphabeta/gammadelta lineage fate

1 reference

12 December 2020

Selection of the cutaneous intraepithelial γδ+ T cell repertoire by a thymic stromal determinant

1 reference

12 December 2020

Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation

1 reference

12 December 2020

10.1016/J.SMIM.2010.04.001

Identifiers

DOI

1 reference

30 July 2017

1 reference

30 July 2017

1 reference