The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate. (Q51081581)

29 March 2018

title

The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate. (English)

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29 March 2018

author name string

Yasutomo K

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29 March 2018

Doyle C

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29 March 2018

Miele L

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29 March 2018

Fuchs C

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29 March 2018

Germain RN

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29 March 2018

language of work or name

English

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publication date

1 March 2000

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29 March 2018

published in

Nature

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29 March 2018

volume

404

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29 March 2018

issue

6777

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29 March 2018

page(s)

506-510

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29 March 2018

Selective events in T cell development

cites work

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T-cell antigen receptor genes and T-cell recognition

21 January 2018

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CD4/CD8 lineage commitment: back to instruction?

21 January 2018

1 reference

CD4/CD8 lineage commitment: matching fate with competence.

21 January 2018

1 reference

An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

21 January 2018

1 reference

Correlating notch signaling with thymocyte maturation

21 January 2018

1 reference

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

21 January 2018

1 reference

MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8

21 January 2018

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Disruption of the CD4-major histocompatibility complex class II interaction blocks the development of CD4(+) T cells in vivo

21 January 2018

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MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus

21 January 2018

1 reference

Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation.

21 January 2018

1 reference

Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.

21 January 2018

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Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways

21 January 2018

1 reference

Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules

21 January 2018

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Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

21 January 2018

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CD3 ligation on immature thymocytes generates antagonist-like signals appropriate for CD8 lineage commitment, independently of T cell receptor specificity

21 January 2018

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How many thymocytes audition for selection?

21 January 2018

1 reference

Differential induction of helper and killer T cells from isolated CD4+CD8+ thymocytes in suspension culture.

21 January 2018

1 reference

The immunological synapse: a molecular machine controlling T cell activation

21 January 2018

1 reference

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

21 January 2018

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.

21 January 2018

1 reference

The influence of the MAPK pathway on T cell lineage commitment

21 January 2018

1 reference

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

21 January 2018

1 reference

Distinct mechanisms of neonatal tolerance induced by dendritic cells and thymic B cells

21 January 2018

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Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

21 January 2018

1 reference

Strong agonist ligands for the T cell receptor do not mediate positive selection of functional CD8+ T cells

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/35006664

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29 March 2018

Dimensions Publication ID

1020920655

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29 March 2018