Transcriptional responses to oxidative stress: pathological and toxicological implications (Q23919656)

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Troglitazone and liver injury: in search of answers

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Insight into hepatotoxicity: The troglitazone experience

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Cellular response to oxidative stress: signaling for suicide and survival

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The p53 pathway and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Role of small heat shock protein HSP25 in radioresistance and glutathione-redox cycle

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Selenocompounds induce a redox modulation of protein kinase C in the cell, compartmentally independent from cytosolic glutathione: its role in inhibition of tumor promotion

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Molecular mechanisms of quinone cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Involvement of growth factor receptors in the mammalian UVC response

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Superoxide and hydrogen peroxide in relation to mammalian cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

1 reference

7 January 2021

JunD reduces tumor angiogenesis by protecting cells from oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Mitochondria, oxidants, and aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

FOXO transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Signaling pathways controlling the production of inflammatory mediators in response to crystalline silica exposure: role of reactive oxygen/nitrogen species

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Mitochondrial redox control of matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Metal-induced oxidative stress and signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Iron, hemochromatosis, and hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oxidative stress in asthma and COPD: antioxidants as a therapeutic strategy

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

alpha-synuclein promotes mitochondrial deficit and oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Are mitochondria a permanent source of reactive oxygen species?

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Redox signalling and transition metals in the control of the p53 pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Regulation of metallothionein gene expression by oxidative stress and metal ions

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Antioxidant-mediated inhibition of the heat shock response leads to apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Isoforms of mammalian peroxiredoxin that reduce peroxides in presence of thioredoxin

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

FoxOs at the crossroads of cellular metabolism, differentiation, and transformation

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

APE/Ref-1 and the mammalian response to genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oxygen free radical generating mechanisms in the colon: do the semiquinones of vitamin K play a role in the aetiology of colon cancer?

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Recent advances towards understanding redox mechanisms in the activation of nuclear factor kappaB.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Protein kinase C signaling and oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oxidative DNA and protein damage in metal-induced toxicity and carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oxygen radicals and signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Regulation of p53 stability and activity in response to genotoxic stress.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Activation of Nrf2 in defense against cadmium-induced oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Xenobiotic-activated receptors: from transcription to drug metabolism to disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Superoxide production by the mitochondrial respiratory chain

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Low oxygen concentration extends the lifespan of cultured human diploid cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Mammalian MAP kinase signalling cascades

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Biochemistry and molecular cell biology of diabetic complications

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Signalling through the lipid products of phosphoinositide-3-OH kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Premature ageing in mice expressing defective mitochondrial DNA polymerase

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Regulation of cellular response to oncogenic and oxidative stress by Seladin-1

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Molecular pathways to neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oxygen sensing by HIF hydroxylases

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Radical medicine: treating ageing to cure disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Integrating cell-signalling pathways with NF-kappaB and IKK function

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Role of oxidative carbonylation in protein quality control and senescence

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Role of redox potential and reactive oxygen species in stress signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The cellular response to p53: the decision between life and death

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Activators and target genes of Rel/NF-kappaB transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Reciprocal down-regulation of p53 and SOD2 gene expression-implication in p53 mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Regulation of the G2/M transition by p53.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

FOXO transcription factors at the interface between longevity and tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

NF-kappaB and the immune response

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Introduction to NF-kappaB: players, pathways, perspectives

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap n collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2)

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Induction of metallothionein l by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zinc

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Brain iron pathways and their relevance to Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Induction of heat shock protein 70 protects mesangial cells against oxidative injury

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Doxorubicin-induced cardiomyopathy

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Involved-field radiotherapy for advanced Hodgkin's lymphoma.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Reactive oxygen generated by Nox1 triggers the angiogenic switch

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oxidative damage and mitochondrial decay in aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kappa B and AP-1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Reactive oxygen species are downstream mediators of p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The elusive function of metallothioneins

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

MEKK1/JNK signaling stabilizes and activates p53.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Nrf2 is essential for protection against acute pulmonary injury in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alpha

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oxidative stress activates metal-responsive transcription factor-1 binding activity. Occupancy in vivo of metal response elements in the metallothionein-I gene promoter

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Transcriptional activation of the human glutathione peroxidase promoter by p53.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-kappaB.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

p38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Chemoprotection by phenolic antioxidants

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Topology of superoxide production from different sites in the mitochondrial electron transport chain

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Superoxide dismutase 1 knock-down induces senescence in human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2·Keap1·Cul3 complex and recruiting Nrf2·Maf to the antioxidant response element enhancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Induction of metallothionein I by arsenic via metal-activated transcription factor 1. Critical role of c-terminal cysteine residues in arsenic sensing

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Energy metabolism in uncoupling protein 3 gene knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

A fascination with enzymes: the journey not the arrival matters

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Tumor necrosis factor alpha and toxicology

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The Evolution of Oxygen As a Biosynthetic Reagent

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Hydrogen peroxide activates NFkappaB and the interleukin-6 promoter through NFkappaB-inducing kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Metal response element (MRE)-binding transcription factor-1 (MTF-1): structure, function, and regulation

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The intracellular localization of APE1/Ref-1: more than a passive phenomenon?

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

FOXO transcription factors in cell-cycle regulation and the response to oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Mechanisms of Cr(VI) induced p53 activation: the role of phosphorylation, mdm2 and ERK

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Induction of apoptosis by the transcription factor c-Jun

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Aging: a theory based on free radical and radiation chemistry

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Role of the heat shock response and molecular chaperones in oncogenesis and cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Protection against Chromium (VI)-induced oxidative stress and apoptosis by Nrf2. Recruiting Nrf2 into the nucleus and disrupting the nuclear Nrf2/Keap1 association

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Is NF-kappaB the sensor of oxidative stress?

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Roles of the heat shock transcription factors in regulation of the heat shock response and beyond

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Metal-responsive transcription factor-1 (MTF-1) is essential for embryonic liver development and heavy metal detoxification in the adult liver

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oxidants in signal transduction: impact on DNA integrity and gene expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Hypoxia-inducible factor as a physiological regulator

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Inhibition of nuclear factor kB by phenolic antioxidants: interplay between antioxidant signaling and inflammatory cytokine expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Molecular Pathways of Neurodegeneration in Parkinson's Disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

A cluster of metabolic defects caused by mutation in a mitochondrial tRNA.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The rise of oxygen over the past 205 million years and the evolution of large placental mammals.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The effect of oxygen on biochemical networks and the evolution of complex life

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Evolution. Oxygen and evolution.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Protein oxidation and aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Leukocyte oxidase: defective activity in chronic granulomatous disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Tumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Role for mitochondrial oxidants as regulators of cellular metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Activity of metal-responsive transcription factor 1 by toxic heavy metals and H2O2 in vitro is modulated by metallothionein

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Metabolism and the control of circadian rhythms

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The Sir2 family of protein deacetylases

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Regulatory mechanisms controlling gene expression mediated by the antioxidant response element

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The role of oxidative stress in carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Free radicals in the physiological control of cell function

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oxidative stress and vascular disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Mitochondrial integrity and function in atherogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Vascular effects following homozygous disruption of p47(phox) : An essential component of NADPH oxidase

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Neuroprotection by hypoxic preconditioning involves oxidative stress-mediated expression of hypoxia-inducible factor and erythropoietin

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Linkage analysis of susceptibility to hyperoxia. Nrf2 is a candidate gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oxygen in the evolution of complex life and the price we pay.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

p47phox is required for atherosclerotic lesion progression in ApoE(-/-) mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Hypoxia and oxidative stress in breast cancer. Hypoxia signalling pathways

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Mechanisms of chromium toxicity, carcinogenicity and allergenicity: review of the literature from 1985 to 2000.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

AP-1 subunits: quarrel and harmony among siblings

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Chromium and manganese levels in the scalp hair of normals and patients with breast cancer.

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: cellular and molecular mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Metal-responsive transcription factor (MTF-1) and heavy metal stress response in Drosophila and mammalian cells: a functional comparison

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Oxidative stress and chromium(VI) carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Occupational exposure to chrysotile asbestos and cancer risk: a review of the amphibole hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Metals, toxicity and oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Induction of CYP1A1. The AhR/DRE paradigm: transcription, receptor regulation, and expanding biological roles

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Vacuolar leukoencephalopathy with widespread astrogliosis in mice lacking transcription factor Nrf2

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Reactive oxygen species in tumor progression

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021

Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.PHARMTHERA.2009.11.004

7 January 2021