Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase (Q22251079)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847880%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

title

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase (English)

1 reference

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18 March 2020

1 reference

1 reference

1 reference

Michael J Jurczak

Michael J

Jurczak

1 reference

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18 March 2020

Gerald I Shulman

Gerald I

Shulman

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18 March 2020

Varman T Samuel

Varman T

Samuel

1 reference

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18 March 2020

Gary W Cline

Gary W

Cline

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18 March 2020

Xian-Man Zhang

Xian-Man

Zhang

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18 March 2020

Sanjay Bhanot

Sanjay

Bhanot

1 reference

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18 March 2020

Joao-Paulo Camporez

Joao-Paulo

Camporez

1 reference

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18 March 2020

Anila K Madiraju

Anila K

Madiraju

1 reference

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18 March 2020

Richard G Kibbey

Richard G

Kibbey

1 reference

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18 March 2020

Yasmeen Rahimi

Yasmeen

Rahimi

1 reference

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18 March 2020

Derek M Erion

Derek M

Erion

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18 March 2020

Demetrios T Braddock

Demetrios T

Braddock

1 reference

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18 March 2020

Ronald A Albright

Ronald A

Albright

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18 March 2020

Brett J Prigaro

Brett J

Prigaro

1 reference

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18 March 2020

John L Wood

John L

Wood

1 reference

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18 March 2020

Michael J MacDonald

Michael J

MacDonald

1 reference

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18 March 2020

Hui-Young Lee

Hui-Young

Lee

1 reference

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18 March 2020

language of work or name

English

0 references

publication date

21 May 2014

1 reference

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18 March 2020

number of pages

1 reference

inferred from page(s)

published in

Nature

1 reference

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18 March 2020

volume

510

1 reference

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18 March 2020

issue

7506

1 reference

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18 March 2020

page(s)

542-546

1 reference

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Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP

18 March 2020

cites work

1 reference

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19 March 2017

1 reference

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The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver

19 March 2017

1 reference

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Role of glycerol 3-phosphate dehydrogenase in glyceride metabolism. Effect of diet on enzyme activities in chicken liver

19 March 2017

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Structure of alpha-glycerophosphate oxidase from Streptococcus sp.: a template for the mitochondrial alpha-glycerophosphate dehydrogenase

19 March 2017

1 reference

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Mouse lacking NAD+-linked glycerol phosphate dehydrogenase has normal pancreatic beta cell function but abnormal metabolite pattern in skeletal muscle

19 March 2017

1 reference

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The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

19 March 2017

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Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

19 March 2017

1 reference

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Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.

7 April 2017

1 reference

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Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

27 September 2017

1 reference

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Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein

27 September 2017

1 reference

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Metabolomic and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle. I. Interrelation between gluconeogenesis and cataplerosis; formation of methoxamates from aminooxyacetate and ketoacids

27 September 2017

1 reference

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Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

27 September 2017

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The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism

27 September 2017

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Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

27 September 2017

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The interaction between the cytosolic pyridine nucleotide redox potential and gluconeogenesis from lactate/pyruvate in isolated rat hepatocytes. Implications for investigations of hormone action

27 September 2017

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Proportional activities of glycerol kinase and glycerol 3-phosphate dehydrogenase in rat hepatomas

27 September 2017

1 reference

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Studies on the active transfer of reducing equivalents into mitochondria via the malate-aspartate shuttle

27 September 2017

1 reference

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Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice

27 September 2017

1 reference

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Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.

30 May 2018

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Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus

30 May 2018

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The problem of tissue sampling from experimental animals with respect to freezing technique, anoxia, stress and narcosis. A new method for sampling rat liver tissue and the physiological values of glycolytic intermediates and related compounds.

30 May 2018

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Characterization of shuttle mechanisms for the transport of reducing equivalents into mitochondria

30 May 2018

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Purification and characterization of glycerol-3-phosphate dehydrogenase (flavin-linked) from rat liver mitochondria

30 May 2018

1 reference

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Isolation and characterization of flavin-linked glycerol-3-phosphate dehydrogenase from rabbit skeletal muscle mitochondria and comparison with the enzyme from rabbit brain

30 May 2018

1 reference

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The redox state of the nicotinamide-adenine dinucleotides in rat liver homogenates

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13270

Normal thyroid thermogenesis but reduced viability and adiposity in mice lacking the mitochondrial glycerol phosphate dehydrogenase

21 January 2018

1 reference

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A high carbohydrate diet does not induce hyperglycaemia in a mitochondrial glycerol-3-phosphate dehydrogenase-deficient mouse.

21 January 2018

1 reference

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Novel hypotensive agents from Verbesina caracasana. 8. Synthesis and pharmacology of (3,4-dimethoxycinnamoyl)-N(1)-agmatine and synthetic analogues

21 January 2018

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Purification and properties of two types of diphosphopyridine nucleotide-linked glycerol 3-phosphate dehydrogenases from chicken breast muscle and chicken liver

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24847880

12 December 2020

inferred from PubMed ID database lookup

Intracellular redox state and stimulation of gluconeogenesis by glucagon and norepinephrine in the perfused rat liver

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24847880

12 December 2020

inferred from PubMed ID database lookup

A glycerol-3-phosphate dehydrogenase null mutant in BALB/cHeA mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24847880

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NATURE13270

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847880%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

18 March 2020

1024050118

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847880%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

PubMed publication ID

24847880

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24847880%20AND%20SRC:MED&resulttype=core&format=json