Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2. (Q42033681)

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scientific article published on 16 February 2006

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English	Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.	scientific article published on 16 February 2006

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2. (English)

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

1 reference

based on heuristic

inferred from title

insulin resistance

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based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

object named as

David B Savage

1

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Gerald I. Shulman

object named as

Gerald I Shulman

13

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Varman T Samuel

3

object named as

Varman T Samuel

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

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object named as

Gary W Cline

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Europe PubMed Central

PMC publication ID

15 October 2017

5

object named as

Dongyan Zhang

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Europe PubMed Central

PMC publication ID

15 October 2017

4

object named as

Zhen-Xiang Liu

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Europe PubMed Central

PMC publication ID

15 October 2017

7

object named as

Xian-Man Zhang

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Europe PubMed Central

PMC publication ID

15 October 2017

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object named as

John G Geisler

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Europe PubMed Central

PMC publication ID

15 October 2017

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object named as

Sanjay Bhanot

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Europe PubMed Central

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15 October 2017

12

object named as

Brett P Monia

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Europe PubMed Central

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15 October 2017

author name string

Cheol Soo Choi

2

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15 October 2017

Amy Wang

6

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Europe PubMed Central

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15 October 2017

Xing Xian Yu

9

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Europe PubMed Central

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15 October 2017

language of work or name

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publication date

16 February 2006

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Europe PubMed Central

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15 October 2017

Journal of Clinical Investigation

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Europe PubMed Central

PMC publication ID

15 October 2017

116

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Europe PubMed Central

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15 October 2017

3

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Europe PubMed Central

PMC publication ID

15 October 2017

817-824

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PMC publication ID

15 October 2017

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

1 reference

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Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice

1 reference

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5 June 2018

Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice

1 reference

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Treating the metabolic syndrome: acetyl-CoA carboxylase inhibition

1 reference

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Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonism

1 reference

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5 June 2018

Severe impairment in liver insulin signaling fails to alter hepatic insulin action in conscious mice

1 reference

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5 June 2018

Mechanisms of insulin resistance in humans and possible links with inflammation

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Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes

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Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery

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Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

1 reference

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Molecular mediators of hepatic steatosis and liver injury

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Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease.

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FoxOs at the crossroads of cellular metabolism, differentiation, and transformation

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Hypothalamic malonyl-CoA as a mediator of feeding behavior

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

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5 June 2018

Regulation of mammalian acetyl-CoA carboxylase

1 reference

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Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy

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Contrasting effects of fish oil and safflower oil on hepatic peroxisomal and tissue lipid content

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Resistin / Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-gamma action in humans

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5 June 2018

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

1 reference

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5 June 2018

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2

1 reference

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5 June 2018

Cellular mechanisms of insulin resistance

1 reference

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5 June 2018

The subcellular localization of acetyl-CoA carboxylase 2

1 reference

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5 June 2018

The regulation of acetyl-CoA carboxylase--a potential target for the action of hypolipidemic agents

1 reference

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The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis

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Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

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Diacylglycerol/protein kinase C signalling: a mechanism for insulin resistance?

1 reference

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Protein kinase C is increased in the liver of humans and rats with non-insulin-dependent diabetes mellitus: an alteration not due to hyperglycemia

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Transient increase in obese gene expression after food intake or insulin administration

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Fatty acid synthesis and its regulation

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Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes

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Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesity

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Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance

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Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men.

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Leptin-replacement therapy for lipodystrophy.

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Fat in all the wrong places

1 reference

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Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy.

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Tissue and isoform-selective activation of protein kinase C in insulin-resistant obese Zucker rats - effects of feeding

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Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression

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17 August 2018

Identifiers

10.1172/JCI27300

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

ResearchGate publication ID

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