Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor (Q22011090)

protein-containing complex assembly

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

M J Bennett

Melanie J.

Bennett

1 reference

Dimensions

6 February 2023

J A Lebrón

series ordinal

author given names

José A.

author last names

Lebrón

1 reference

Dimensions

6 February 2023

P J Bjorkman

series ordinal

author given names

Pamela J.

author last names

Bjorkman

1 reference

Dimensions

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

6 February 2023

language of work or name

English

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publication date

6 January 2000

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published in

Nature

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volume

403

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issue

6765

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page(s)

46-53

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cites work

1 reference

Structural basis of T cell recognition

21 January 2018

1 reference

Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor

21 January 2018

1 reference

The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression

21 January 2018

1 reference

Hereditary hemochromatosis: effects of C282Y and H63D mutations on association with beta2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells

21 January 2018

1 reference

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

21 January 2018

1 reference

Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis

21 January 2018

1 reference

21 January 2018

1 reference

The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells

21 January 2018

1 reference

The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor

21 January 2018

1 reference

Co-trafficking of HFE, a nonclassical major histocompatibility complex class I protein, with the transferrin receptor implies a role in intracellular iron regulation

21 January 2018

1 reference

Crystal structure of the ectodomain of human transferrin receptor

21 January 2018

1 reference

Structural model of phospholipid-reconstituted human transferrin receptor derived by electron microscopy

21 January 2018

1 reference

Principles of protein-protein interactions

21 January 2018

1 reference

MultiCoil: a program for predicting two- and three-stranded coiled coils

21 January 2018

1 reference

Refined crystal structure of the seryl-tRNA synthetase from Thermus thermophilus at 2.5 A resolution

21 January 2018

1 reference

The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 1999.

21 January 2018

1 reference

Structure of human lactoferrin: crystallographic structure analysis and refinement at 2.8 A resolution

21 January 2018

1 reference

The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells

21 January 2018

1 reference

Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract

21 January 2018

1 reference

Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum

21 January 2018

1 reference

Unusual MHC-like molecules: CD1, Fc receptor, the hemochromatosis gene product, and viral homologs

21 January 2018

1 reference

Regulation of insulin receptor functions by a peptide derived from a major histocompatibility complex class I antigen

21 January 2018

1 reference

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods.

21 January 2018

1 reference

Template convolution to enhance or detect structural features in macromolecular electron-density maps

21 January 2018

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

Raster3D Version 2.0. A program for photorealistic molecular graphics

21 January 2018

1 reference

SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

21 January 2018

1 reference

Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family

21 January 2018

1 reference

Molecular medicine and hemochromatosis: at the crossroads

21 January 2018

1 reference

7 January 2021

The transferrin receptor binding site on HFE, the class I MHC-related protein mutated in hereditary hemochromatosis

1 reference

7 January 2021

Two novel missense mutations of the HFE gene (I105T and G93R) and identification of the S65C mutation in Alabama hemochromatosis probands

1 reference

7 January 2021

The anion requirement for iron release from transferrin is preserved in the receptor-transferrin complex

1 reference

7 January 2021

A new role for the transferrin receptor in the release of iron from transferrin

1 reference

7 January 2021

Functional analysis of human/chicken transferrin receptor chimeras indicates that the carboxy-terminal region is important for ligand binding

1 reference

7 January 2021

The CCP4 suite: programs for protein crystallography

1 reference

7 January 2021

Identifiers

DOI

10.1038/47417

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