Protein tyrosine phosphatase non-receptor type 14 (Q21120492)

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mammalian protein found in Homo sapiens

protein-tyrosine phosphatase pez
PTPN14
cytoskeletal-associated protein tyrosine phosphatase
tyrosine-protein phosphatase non-receptor type 14

Language	Label	Description	Also known as
English	Protein tyrosine phosphatase non-receptor type 14	mammalian protein found in Homo sapiens	protein-tyrosine phosphatase pez PTPN14 cytoskeletal-associated protein tyrosine phosphatase tyrosine-protein phosphatase non-receptor type 14

Statements

1 reference

13 November 2019

UniProt protein ID

Protein-tyrosine phosphatase, non-receptor type-14, -21

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

Ubiquitin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

Protein-tyrosine phosphatase-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

FERM/acyl-CoA-binding protein superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

PH-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

FERM superfamily, second domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

Tyrosine specific protein phosphatases domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Band 4.1 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM central domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM, C-terminal PH-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PTP type protein phosphatase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

FERM conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

phosphoprotein phosphatase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

hydrolase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

phosphatase activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

receptor tyrosine kinase binding

determination method or standard

1 reference

8 April 2019

Protein tyrosine phosphatase PTPN14 is a regulator of lymphatic function and choanal development in humans

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

transcription coregulator activity

determination method or standard

1 reference

8 April 2019

PTPN14 interacts with and negatively regulates the oncogenic function of YAP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

protein binding

determination method or standard

6 references

8 April 2019

PTPN14 interacts with and negatively regulates the oncogenic function of YAP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

8 April 2019

PTPN14 is required for the density-dependent control of YAP1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

8 April 2019

AMPK modulates Hippo pathway activity to regulate energy homeostasis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

8 April 2019

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

8 April 2019

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

8 April 2019

Ligand binding to WW tandem domains of YAP2 transcriptional regulator is under negative cooperativity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

protein tyrosine phosphatase activity

determination method or standard

4 references

8 April 2019

Pez: a novel human cDNA encoding protein tyrosine phosphatase- and ezrin-like domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

8 April 2019

PTPN14 interacts with and negatively regulates the oncogenic function of YAP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

8 April 2019

PTPN14 interacts with and negatively regulates the oncogenic function of YAP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

8 April 2019

Translocation of protein tyrosine phosphatase Pez/PTPD2/PTP36 to the nucleus is associated with induction of cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

8 April 2019

PTPN14 interacts with and negatively regulates the oncogenic function of YAP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

8 April 2019

Translocation of protein tyrosine phosphatase Pez/PTPD2/PTP36 to the nucleus is associated with induction of cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

biological process

negative regulation of cell population proliferation

determination method or standard

1 reference

8 April 2019

PTPN14 is required for the density-dependent control of YAP1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

regulation of transcription, DNA-templated

determination method or standard

1 reference

31 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15678&geneProductId=UniProtKB:Q15678

determination method or standard

regulation of protein export from nucleus

determination method or standard

1 reference

8 April 2019

PTPN14 is required for the density-dependent control of YAP1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

31 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15678&geneProductId=UniProtKB:Q15678

determination method or standard

dephosphorylation

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

peptidyl-tyrosine dephosphorylation

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

cellular response to cytokine stimulus

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

regulation of nucleic acid-templated transcription

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15678

determination method or standard

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

Protein-tyrosine phosphatase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

FERM conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

FERM, C-terminal PH-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

Band 4.1 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

Tyrosine specific protein phosphatases domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

Protein-tyrosine phosphatase, catalytic

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

FERM central domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

FERM, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

PTP type protein phosphatase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15678

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000355923

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000355923

ENSP00000443330

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000443330

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

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Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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