PTPN14 interacts with and negatively regulates the oncogenic function of YAP (Q24316475)

GOA release 2020-03-11

author name string

X Liu

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N Yang

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S A Figel

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K E Wilson

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C D Morrison

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I H Gelman

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J Zhang

α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1

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language of work or name

English

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publication date

7 March 2013

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1266-73

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cites work

1 reference

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

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TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm

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Physical interaction with Yes-associated protein enhances p73 transcriptional activity

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Translocation of protein tyrosine phosphatase Pez/PTPD2/PTP36 to the nucleus is associated with induction of cell proliferation

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The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules

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19 March 2017

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WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus

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salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

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KIBRA Regulates Hippo Signaling Activity via Interactions with Large Tumor Suppressor Kinases

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27 September 2017

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27 September 2017

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Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

27 September 2017

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Regulation of phosphorylation level and distribution of PTP36, a putative protein tyrosine phosphatase, by cell-substrate adhesion

27 September 2017

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Effects of overexpression of PTP36, a putative protein tyrosine phosphatase, on cell adhesion, cell growth, and cytoskeletons in HeLa cells

27 September 2017

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cDNA cloning of a novel protein tyrosine phosphatase with homology to cytoskeletal protein 4.1 and its expression in T-lineage cells

27 September 2017

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Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

27 September 2017

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https://api.crossref.org/works/10.1038%2FONC.2012.147

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.147

Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.147

Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.147

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.147

1 reference

Dimensions Publication ID

1039640337

0 references

1 reference

1 reference

PubMed publication ID

22525271

1 reference