Pharmacokinetics of chlorproguanil, dapsone, artesunate and their major metabolites in patients during treatment of acute uncomplicated Plasmodium falciparum malaria. (Q45973898)

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English	Pharmacokinetics of chlorproguanil, dapsone, artesunate and their major metabolites in patients during treatment of acute uncomplicated Plasmodium falciparum malaria.	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

Pharmacokinetics of chlorproguanil, dapsone, artesunate and their major metabolites in patients during treatment of acute uncomplicated Plasmodium falciparum malaria. (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

Plasmodium falciparum

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inferred from title

pharmacokinetics

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author name string

Ann K Miller

1

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

Nibedita Bandyopadhyay

2

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

Daniel G Wootton

3

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

Stephan Duparc

4

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

Paula L Kirby

5

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

Peter A Winstanley

6

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

Stephen A Ward

7

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

publication date

11 June 2009

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

European Journal of Clinical Pharmacology

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

65

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

10

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

977-987

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

The role of S-mephenytoin hydroxylase (CYP2C19) in the metabolism of the antimalarial biguanides

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https://api.crossref.org/works/10.1007%2FS00228-009-0672-1

21 January 2018

Drug-resistant malaria

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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inferred from PubMed ID database lookup

Clinical pharmacokinetics of dapsone

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Antimalarial bioavailability and disposition of artesunate in acute falciparum malaria

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Adverse effects in patients with acute falciparum malaria treated with artemisinin derivatives

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Slow chloroguanide metabolism in Tanzanians compared with white subjects and Asian subjects confirms a decreased CYP2C19 activity in relation to genotype

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Declining concentrations of dihydroartemisinin in plasma during 5-day oral treatment with artesunate for Falciparum malaria.

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Comparative pharmacokinetics and effect kinetics of orally administered artesunate in healthy volunteers and patients with uncomplicated falciparum malaria

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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The polymorphic acetylation of dapsone in man

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Artemisinin antimalarials moderately affect cytochrome P450 enzyme activity in healthy subjects

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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A pharmacokinetic and pharmacodynamic study of intravenous vs oral artesunate in uncomplicated falciparum malaria.

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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The economic and social burden of malaria

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Oral artesunate dose-response relationship in acute falciparum malaria

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Major pitfalls in the measurement of artemisinin derivatives in plasma in clinical studies

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Chlorproguanil-dapsone (LAPDAP) for uncomplicated falciparum malaria

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Concentration and time dependency of artemisinin efficacy against Plasmodium falciparum in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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CYP2C8/9 mediate dapsone N-hydroxylation at clinical concentrations of dapsone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Chlorproguanil-dapsone versus sulfadoxine-pyrimethamine for sequential episodes of uncomplicated falciparum malaria in Kenya and Malawi: a randomised clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Absence of time-dependent artesunate pharmacokinetics in healthy subjects during 5-day oral administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate Pyrimethamine/Sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Artesunate/mefloquine treatment of multi-drug resistant falciparum malaria

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Open-label comparative clinical study of chlorproguanil-dapsone fixed dose combination (Lapdap) alone or with three different doses of artesunate for uncomplicated Plasmodium falciparum malaria

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Oral bioavailability of dihydroartemisinin in Vietnamese volunteers and in patients with falciparum malaria

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Comparison of the metabolism and toxicity of dapsone in rat, mouse and man

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Chlorproguanil/dapsone for uncomplicated Plasmodium falciparum malaria in young children: pharmacokinetics and therapeutic range

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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A comparison of oral artesunate and artemether antimalarial bioactivities in acute falciparum malaria

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Absence of an interaction between artesunate and atovaquone--proguanil

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Artemether-lumefantrine for the treatment of multidrug-resistant falciparum malaria

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https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

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Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/19517101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00228-009-0672-1

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

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release_jbjnvhgxnva5dl7uppcodjbvqi

1 reference

https://api.fatcat.wiki/v0/release/jbjnvhgxnva5dl7uppcodjbvqi

24 November 2022

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19517101

ResearchGate publication ID

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