Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development (Q28593302)

31 January 2017

title

Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development (English)

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Hypoxia inducible factor 1, alpha subunit

31 January 2017

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GOA release 2020-03-11

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Gregg L. Semenza

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31 January 2017

Yves D. Pastore

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31 January 2017

Donghoon Yoon

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31 January 2017

Vladimir Divoky

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31 January 2017

Enli Liu

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31 January 2017

Agnieszka E. Mlodnicka

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31 January 2017

Karin Rainey

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31 January 2017

Premysl Ponka

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31 January 2017

Armin Schumacher

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31 January 2017

Josef T. Prchal

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31 January 2017

language of work or name

English

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publication date

1 September 2006

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

281

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31 January 2017

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31 January 2017

page(s)

25703–25711

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A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

31 January 2017

cites work

1 reference

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21 January 2018

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α

21 January 2018

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Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

21 January 2018

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

21 January 2018

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Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1alpha

21 January 2018

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Multilineage embryonic hematopoiesis requires hypoxic ARNT activity

21 January 2018

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

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Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

21 January 2018

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Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia

21 January 2018

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Defective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell death

21 January 2018

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A study of intracellular iron metabolism using pyridoxal isonicotinoyl hydrazone and other synthetic chelating agents

21 January 2018

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Dysregulation of ferroportin 1 interferes with spleen organogenesis in polycythaemia mice

21 January 2018

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The molecular circuitry regulating the switch between iron deficiency and overload in mice

21 January 2018

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Disruption of ferroportin 1 regulation causes dynamic alterations in iron homeostasis and erythropoiesis in polycythaemia mice

21 January 2018

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Thrombopoietin promotes mixed lineage and megakaryocytic colony-forming cell growth but inhibits primitive and definitive erythropoiesis in cells isolated from early murine yolk sacs

21 January 2018

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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

21 January 2018

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

21 January 2018

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21 January 2018

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21 January 2018

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HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.

21 January 2018

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HIF-2alpha regulates murine hematopoietic development in an erythropoietin-dependent manner

21 January 2018

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21 January 2018

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The role of erythropoietin in regulating angiogenesis

21 January 2018

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Erythropoietin (Epo) and EpoR expression and 2 waves of erythropoiesis.

21 January 2018

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HIF-1-mediated activation of transferrin receptor gene transcription by iron chelation

21 January 2018

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Oxygen-regulated Transferrin Expression Is Mediated by Hypoxia-inducible Factor-1

21 January 2018

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A novel mammalian iron-regulated protein involved in intracellular iron metabolism

21 January 2018

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Role of the ferroportin iron-responsive element in iron and nitric oxide dependent gene regulation

21 January 2018

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21 January 2018

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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

21 January 2018

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Hepcidin inhibits in vitro erythroid colony formation at reduced erythropoietin concentrations

21 January 2018

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21 January 2018

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Transferrin receptor induction by hypoxia. HIF-1-mediated transcriptional activation and cell-specific post-transcriptional regulation

21 January 2018

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M602329200

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M602329200

Hypoxia affects mesoderm and enhances hemangioblast specification during early development

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M602329200

Identification of a hypoxia response element in the transferrin receptor gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M602329200

Oxygen tension modulates beta-globin switching in embryoid bodies.

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M602329200

Identifiers

DOI

10.1074/JBC.M602329200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017