Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice (Q28513971)

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14716311%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

title

Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice (English)

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14716311%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference

GOA release 2020-03-11

MutL homolog 1

1 reference

GOA release 2020-03-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14716311%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Matthew D Scharff

1 reference

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17 November 2019

Kaichun Wei

2 references

25 January 2017

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17 November 2019

Ziqiang Li

2 references

25 January 2017

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17 November 2019

Alberto Martin

2 references

25 January 2017

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17 November 2019

Tchaiko Parris

2 references

25 January 2017

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17 November 2019

Winfried Edelmann

2 references

25 January 2017

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17 November 2019

Caroline J Woo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14716311%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Stephen Z Sack

1 reference

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17 November 2019

language of work or name

English

0 references

publication date

11 January 2004

1 reference

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17 November 2019

2 references

25 January 2017

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17 November 2019

2 references

25 January 2017

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17 November 2019

2 references

25 January 2017

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17 November 2019

page(s)

224-229

1 reference

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17 November 2019

1 reference

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

21 January 2018

1 reference

Linking class-switch recombination with somatic hypermutation

21 January 2018

1 reference

21 January 2018

Marginal-zone B cells

1 reference

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

21 January 2018

1 reference

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

21 January 2018

1 reference

AID mediates hypermutation by deaminating single stranded DNA.

21 January 2018

1 reference

Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

21 January 2018

1 reference

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

21 January 2018

1 reference

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

21 January 2018

1 reference

DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

21 January 2018

1 reference

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

21 January 2018

1 reference

Mammalian DNA mismatch repair

21 January 2018

1 reference

Roles for mismatch repair factors in regulating genetic recombination

21 January 2018

1 reference

Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair

21 January 2018

1 reference

GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells

21 January 2018

1 reference

Biochemistry and genetics of eukaryotic mismatch repair

21 January 2018

1 reference

A role for exonuclease I from S. pombe in mutation avoidance and mismatch correction.

21 January 2018

1 reference

Human exonuclease I is required for 5' and 3' mismatch repair

21 January 2018

1 reference

Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2

21 January 2018

1 reference

Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae

21 January 2018

1 reference

The interaction of DNA mismatch repair proteins with human exonuclease I

21 January 2018

1 reference

exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair

21 January 2018

1 reference

Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility

21 January 2018

1 reference

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

21 January 2018

1 reference

Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination.

21 January 2018

1 reference

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions

21 January 2018

1 reference

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affinity maturation develops in two stages of clonal selection.

21 January 2018

1 reference

Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process

21 January 2018

1 reference

Induction of somatic mutation in a human B cell line in vitro

21 January 2018

1 reference

Expression of error-prone polymerases in BL2 cells activated for Ig somatic hypermutation

21 January 2018

1 reference

Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin

21 January 2018

1 reference

Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity

21 January 2018

1 reference

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

21 January 2018

1 reference

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

21 January 2018

1 reference

Severe attenuation of the B cell immune response in Msh2-deficient mice

21 January 2018

1 reference

Bcl-2 rescues the germinal center response but does not alter the V gene somatic hypermutation spectrum in MSH2-deficient mice.

21 January 2018

1 reference

Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2

21 January 2018

1 reference

Mlh1 Can Function in Antibody Class Switch Recombination Independently of Msh2

21 January 2018

1 reference

Somatic hypermutation of immunoglobulin genes: merging mechanisms for genetic diversity

21 January 2018

1 reference

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

21 January 2018

1 reference

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

21 January 2018

1 reference

Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction

21 January 2018

1 reference

Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiae

21 January 2018

1 reference

Testing the reverse transcriptase model of somatic mutation

21 January 2018

1 reference

Progress in understanding the mechanism and consequences of somatic hypermutation

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

AID and mismatch repair in antibody diversification

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

The influence of transcriptional orientation on endogenous switch region function

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NI1031

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14716311%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14716311%20AND%20SRC:MED&resulttype=core&format=json