The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues (Q28510383)

25 January 2017

title

The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues (English)

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dendritic cell proliferation

25 January 2017

main subject

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Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0044565

FMS-like tyrosine kinase 3

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GOA release 2020-03-11

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Claudia Waskow

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Pierre Guermonprez

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Michel C. Nussenzweig

object named as

Michel Nussenzweig

1 reference

25 January 2017

Miriam Merad

1 reference

25 January 2017

Florent Ginhoux

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25 January 2017

Guillaume Darrasse-Jeze

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ORCID Public Data File 2021

Kang Liu

1 reference

25 January 2017

Guillaume Darrasse-Jèze

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25 January 2017

Tamara Shengelia

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25 January 2017

Kaihui Yao

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25 January 2017

language of work or name

English

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publication date

1 June 2008

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25 January 2017

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25 January 2017

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25 January 2017

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25 January 2017

page(s)

676–683

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Langerhans cells arise from monocytes in vivo

25 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Taking dendritic cells into medicine

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Tolerogenic dendritic cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Monocytes give rise to mucosal, but not splenic, conventional dendritic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Interpreting flow cytometry data: a guide for the perplexed

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

The early progenitors of mouse dendritic cells and plasmacytoid predendritic cells are within the bone marrow hemopoietic precursors expressing Flt3

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Characterization of a common precursor population for dendritic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow.

2 June 2018

1 reference

Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo

21 January 2018

1 reference

Origin of dendritic cells in peripheral lymphoid organs of mice.

21 January 2018

1 reference

Intrinsic lymphotoxin-beta receptor requirement for homeostasis of lymphoid tissue dendritic cells.

21 January 2018

1 reference

Antigen transmission by replicating antigen-bearing dendritic cells

21 January 2018

1 reference

Inhibition of natural type I IFN-producing and dendritic cell development by a small molecule receptor tyrosine kinase inhibitor with Flt3 affinity

21 January 2018

1 reference

Development of CD8 -Positive Dendritic Cells from a Common Myeloid Progenitor

21 January 2018

1 reference

Development of thymic and splenic dendritic cell populations from different hemopoietic precursors.

21 January 2018

1 reference

Ontogeny and innate properties of neonatal dendritic cells

21 January 2018

1 reference

Plasmacytoid dendritic cells activate lymphoid-specific genetic programs irrespective of their cellular origin.

21 January 2018

1 reference

STAT3 is required for Flt3L-dependent dendritic cell differentiation

21 January 2018

1 reference

Rescue of lethal c-KitW/W mice by erythropoietin

21 January 2018

1 reference

Development of the dendritic cell system during mouse ontogeny

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746085

Hematologic effects of flt3 ligand in vivo in mice

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469816

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A Clonogenic Bone Marrow Progenitor Specific for Macrophages and Dendritic Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469816

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.1615

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Dimensions Publication ID

1046774349

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