YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation (Q28507494)

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English	YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation	scientific journal article

Statements

scholarly article

1 reference

PubMed publication ID

24 January 2017

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation (English)

1 reference

PubMed publication ID

24 January 2017

Smoothened, frizzled class receptor

1 reference

GOA release 2020-03-11

Insulin receptor substrate 1

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Yes-associated protein 1

1 reference

GOA release 2020-03-11

TEA domain family member 1

1 reference

GOA release 2020-03-11

Stephane Angers

6

object named as

Stephane Angers

1 reference

PubMed publication ID

24 January 2017

Paul A Northcott

2

object named as

Paul A. Northcott

1 reference

PubMed publication ID

24 January 2017

author name string

Africa Fernandez-L

1

1 reference

PubMed publication ID

24 January 2017

James Dalton

3

1 reference

PubMed publication ID

24 January 2017

Charles Fraga

4

1 reference

PubMed publication ID

24 January 2017

David Ellison

5

1 reference

PubMed publication ID

24 January 2017

Michael D. Taylor

7

1 reference

PubMed publication ID

24 January 2017

Anna Marie Kenney

8

1 reference

PubMed publication ID

24 January 2017

publication date

1 December 2009

1 reference

PubMed publication ID

24 January 2017

Genes & Development

1 reference

PubMed publication ID

24 January 2017

23

1 reference

PubMed publication ID

24 January 2017

23

1 reference

PubMed publication ID

24 January 2017

2729–2741

1 reference

PubMed publication ID

24 January 2017

The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788333

19 March 2017

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788333

19 March 2017

Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788333

19 March 2017

TEAD mediates YAP-dependent gene induction and growth control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788333

19 March 2017

YAP1 increases organ size and expands undifferentiated progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788333

19 March 2017

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788333

19 March 2017

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

1 reference

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19 March 2017

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

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19 March 2017

Medulloblastoma: developmental mechanisms out of control

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19 March 2017

Expression of cIAP1, a target for 11q22 amplification, correlates with resistance of cervical cancers to radiotherapy

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A mouse model for medulloblastoma and basal cell nevus syndrome

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Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

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19 March 2017

Sonic hedgehog regulates the growth and patterning of the cerebellum

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19 March 2017

A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator

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19 March 2017

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

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Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system

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A perivascular niche for brain tumor stem cells

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7 April 2017

YAP regulates neural progenitor cell number via the TEA domain transcription factor

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Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features

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29 September 2017

Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors

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29 September 2017

The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals

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29 September 2017

PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

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29 September 2017

Morphogens and the control of cell proliferation and patterning in the spinal cord

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Nuclear insulin receptor substrate-1 activates promoters of cell cycle progression genes

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29 September 2017

Filling out the Hippo pathway

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788333

29 September 2017

Hippo signaling in organ size control

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788333

29 September 2017

Hit 'em where they live: targeting the cancer stem cell niche

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IGF-I mediated survival pathways in normal and malignant cells

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Modeling medulloblastoma with genetically engineered mice

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The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas

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29 September 2017

Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors

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A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes.

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Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors

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Identifiers

10.1101/GAD.1824509

1 reference

Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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