Pancreatic β-cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis (Q28476371)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

Pancreatic β-cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis (English)

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10 February 2020

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1 reference

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10 February 2020

J Jason Collier

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10 February 2020

Susan J Burke

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10 February 2020

Mary E Eisenhauer

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10 February 2020

Danhong Lu

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10 February 2020

Renee C Sapp

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10 February 2020

Carlie J Frydman

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publication date

29 July 2011

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10 February 2020

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e22485

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Creative Commons Attribution 4.0 International

10 February 2020

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29 July 2011

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April 2022 Public Data File from Crossref

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cites work

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Nitric oxides mediates a shift from early necrosis to late apoptosis in cytokine-treated β-cells that is associated with irreversible DNA damage.

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29 September 2017

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29 September 2017

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beta-Cell death during progression to diabetes

29 September 2017

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Nitric oxide can inhibit apoptosis or switch it into necrosis

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

29 September 2017

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IL-1 produced and released endogenously within human islets inhibits beta cell function

29 September 2017

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The role of interleukin-1 in the pathogenesis of IDDM.

29 September 2017

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Physiology and pathophysiology of nitric oxide.

29 September 2017

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Apoptosis: the biochemistry and molecular biology of programmed cell death

29 September 2017

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29 September 2017

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Essential contribution of macrophages to islet cell destruction in vivo and in vitro

29 September 2017

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Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide

29 September 2017

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Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

29 September 2017

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Quorum sensing controls biofilm formation in Vibrio cholerae through modulation of cyclic di-GMP levels and repression of vpsT

2 June 2018

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Free radical modulation of insulin release in INS-1 cells exposed to alloxan

2 June 2018

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A role for nitric oxide and other inflammatory mediators in cytokine-induced pancreatic beta-cell dysfunction and destruction

2 June 2018

1 reference

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Irreversible Inhibition of Metabolic Function and Islet Destruction after a 36-Hour Exposure to Interleukin-1β*

2 June 2018

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Nitric Oxide Inhibits Apoptosis by Preventing Increases in Caspase-3-like Activity via Two Distinct Mechanisms

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146470

Dual functional effects of interleukin-1beta on purine nucleotides and insulin secretion in rat islets and INS-1 cells

2 June 2018

1 reference

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Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin.

2 June 2018

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Polyvinylpyrrolidone as a Blocking Agent in Immunochemical Studies

2 June 2018

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Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry.

21 January 2018

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Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets

21 January 2018

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Nitric oxide donors inhibit formation of the Apaf-1/caspase-9 apoptosome and activation of caspases

21 January 2018

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Attenuation of murine collagen-induced arthritis by a novel, potent, selective small molecule inhibitor of IkappaB Kinase 2, TPCA-1 (2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), occurs via reduction of proinflammatory cytokin

21 January 2018

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beta-cell apoptosis and defense mechanisms: lessons from type 1 diabetes

21 January 2018

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Antitumor effects of photodynamic therapy are potentiated by 2-methoxyestradiol. A superoxide dismutase inhibitor.

21 January 2018

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Rapamycin induces autophagy in islets: relevance in islet transplantation

21 January 2018

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Protection of islets by in situ peptide-mediated transduction of the Ikappa B kinase inhibitor Nemo-binding domain peptide.

21 January 2018

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Necrosis Is the Predominant Type of Islet Cell Death During Development of Insulin-Dependent Diabetes Mellitus in BB Rats

21 January 2018

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Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells

27 November 2018

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Immunosuppressive effects of apoptotic cells

27 November 2018

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Protection of human islets from the effects of interleukin-1beta by adenoviral gene transfer of an Ikappa B repressor

21 January 2018

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12 December 2020

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis

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12 December 2020

Immunolocalization of caspase-3 in pancreatic islets of NOD mice during cyclophosphamide-accelerated diabetes

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12 December 2020

Islet cytotoxicity of interleukin 1. Influence of culture conditions and islet donor characteristics

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12 December 2020

Destruction of rat islet cell monolayers by cytokines. Synergistic interactions of interferon-gamma, tumor necrosis factor, lymphotoxin, and interleukin 1

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12 December 2020

Interleukin-1 inhibits glucose-modulated insulin and glucagon secretion in rat islet monolayer cultures

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12 December 2020

Reactive oxygen intermediates in autoimmune islet cell destruction of the NOD mouse induced by peritoneal exudate cells (rich in macrophages) but not T cells

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12 December 2020

Transgenic overexpression of human Bcl-2 in islet β cells inhibits apoptosis but does not prevent autoimmune destruction

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12 December 2020

10.1371/JOURNAL.PONE.0022485

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

21829464

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829464%20AND%20SRC:MED&resulttype=core&format=json