beta-Cell death during progression to diabetes (Q34462324)

2 August 2017

1 reference

title

beta-Cell death during progression to diabetes (English)

1 reference

2 August 2017

1 reference

Mathis D

1 reference

2 August 2017

Vence L

series ordinal

1 reference

2 August 2017

Benoist C

series ordinal

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 December 2001

1 reference

2 August 2017

1 reference

2 August 2017

volume

414

1 reference

2 August 2017

issue

6865

1 reference

2 August 2017

page(s)

792-798

1 reference

Insulin-dependent diabetes mellitus

2 August 2017

cites work

1 reference

7 January 2021

Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes

1 reference

7 January 2021

Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens

1 reference

7 January 2021

T helper cell subsets in insulin-dependent diabetes

1 reference

7 January 2021

Genetic control of diabetes progression

1 reference

7 January 2021

Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model.

1 reference

7 January 2021

Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat.

1 reference

7 January 2021

Apoptosis in the pancreatic islet cells of the neonatal rat is associated with a reduced expression of insulin-like growth factor II that may act as a survival factor

1 reference

7 January 2021

Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes?

1 reference

7 January 2021

Beta-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy

1 reference

7 January 2021

The induction of tolerance by dendritic cells that have captured apoptotic cells

1 reference

7 January 2021

Apoptosis and antiphospholipid antibodies

1 reference

7 January 2021

Apoptosis in development

1 reference

7 January 2021

Interdigital cell death can occur through a necrotic and caspase-independent pathway.

1 reference

7 January 2021

Programmed cell death in animal development

1 reference

7 January 2021

Hormonal and metabolic changes in the perinatal period

1 reference

7 January 2021

Intolerable secretion in tolerant transgenic mice

1 reference

7 January 2021

Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

1 reference

7 January 2021

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

1 reference

7 January 2021

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

1 reference

7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

1 reference

7 January 2021

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

1 reference

7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

7 January 2021

Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation

1 reference

7 January 2021

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

1 reference

7 January 2021

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

1 reference

7 January 2021

The immune response to islets in experimental diabetes and insulin-dependent diabetes mellitus

1 reference

7 January 2021

Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry?

1 reference

7 January 2021

A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes

1 reference

7 January 2021

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

1 reference

7 January 2021

Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions

1 reference

7 January 2021

Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients

1 reference

7 January 2021

Beta cell apoptosis in T cell-mediated autoimmune diabetes

1 reference

7 January 2021

Autoimmune insulitis and diabetes in the absence of antigen-specific contact between T cells and islet beta-cells

1 reference

7 January 2021

Beta cell destruction in the development of autoimmune diabetes in the non-obese diabetic (NOD) mouse

1 reference

7 January 2021

Apoptosis is the mode of beta-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse

1 reference

7 January 2021

Reduced Incidence and Delayed Onset of Diabetes in Perforin-deficient Nonobese Diabetic Mice

1 reference

7 January 2021

Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic mice

1 reference

7 January 2021

Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity

1 reference

7 January 2021

Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes.

1 reference

7 January 2021

Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma.

1 reference

7 January 2021

CD95's deadly mission in the immune system

1 reference

7 January 2021

The role of Fas in autoimmune diabetes

1 reference

7 January 2021

Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1beta and Fas ligation

1 reference

7 January 2021

Requirement of Fas for the Development of Autoimmune Diabetes in Nonobese Diabetic Mice

1 reference

7 January 2021

Mechanisms of beta cell death in diabetes: a minor role for CD95.

1 reference

7 January 2021

Apoptosis of pancreatic beta-cells detected in accelerated diabetes of NOD mice: no role of Fas-Fas ligand interaction in autoimmune diabetes

1 reference

7 January 2021

Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders.

1 reference

7 January 2021

Inhibition of autoimmune diabetes by Fas ligand: the paradox is solved

1 reference

7 January 2021

Significant role for Fas in the pathogenesis of autoimmune diabetes.

1 reference

7 January 2021

A mouse CD8 T cell-mediated acute autoimmune diabetes independent of the perforin and Fas cytotoxic pathways: possible role of membrane TNF.

1 reference

7 January 2021

Monitoring gene expression of TNFR family members by beta-cells during development of autoimmune diabetes

1 reference

7 January 2021

Accelerated beta-cell destruction in adoptively transferred autoimmune diabetes correlates with an increased expression of the genes coding for TNF-alpha and granzyme A in the intra-islet infiltrates

1 reference

7 January 2021

Apoptotic cell death triggered by nitric oxide in pancreatic beta-cells

1 reference

7 January 2021

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

1 reference

7 January 2021

In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha.

1 reference

7 January 2021

Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase

1 reference

7 January 2021

Macrophage cytotoxicity towards isolated rat islet cells: neither lysis nor its protection by nicotinamide are Beta-cell specific

1 reference

7 January 2021

Nitric oxide production in islets from nonobese diabetic mice: aminoguanidine-sensitive and -resistant stages in the immunological diabetic process.

1 reference

7 January 2021

Nitric Oxide Primes Pancreatic β Cells for Fas-mediated Destruction in Insulin-dependent Diabetes Mellitus

1 reference

7 January 2021

Sensitivity of human pancreatic islets to peroxynitrite-induced cell dysfunction and death

1 reference

7 January 2021

Cytotoxic effects of cytokines on rat islets: evidence for involvement of free radicals and lipid peroxidation

1 reference

7 January 2021

Protection of insulin-producing RINm5F cells against cytokine-mediated toxicity through overexpression of antioxidant enzymes

1 reference

7 January 2021

Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production

1 reference

7 January 2021

Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes

1 reference

7 January 2021

Unusual resistance of ALR/Lt mouse beta cells to autoimmune destruction: role for beta cell-expressed resistance determinants

1 reference

7 January 2021

Transgenic overexpression of human Bcl-2 in islet β cells inhibits apoptosis but does not prevent autoimmune destruction

1 reference

7 January 2021

Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury

1 reference

7 January 2021

Deconstructing type 2 diabetes

1 reference

7 January 2021

Human type 2 diabetes: morphological evidence for abnormal beta-cell function

1 reference

7 January 2021

No decrease of the beta-cell mass in type 2 diabetic patients

1 reference

7 January 2021

High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program

1 reference

7 January 2021

Irreversibility of nutritionally induced NIDDM in Psammomys obesus is related to beta-cell apoptosis

1 reference

7 January 2021

Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes.

1 reference

7 January 2021

beta-cell glucotoxicity in the Psammomys obesus model of type 2 diabetes

1 reference

7 January 2021

Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes

1 reference

7 January 2021

Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration

1 reference

7 January 2021

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

1 reference

7 January 2021

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

1 reference

7 January 2021

Glucose stimulates the activity of the guanine nucleotide-exchange factor eIF-2B in isolated rat islets of Langerhans

1 reference

7 January 2021

EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome

1 reference

7 January 2021

Following a diabetogenic T cell from genesis through pathogenesis

1 reference

7 January 2021

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

1 reference

7 January 2021

Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma

1 reference

7 January 2021

Identifiers

DOI

10.1038/414792A

1 reference

2 August 2017

1 reference