Antisense-induced down-regulation of thymidylate synthase and enhanced cytotoxicity of 5-FUdR in 5-FUdR-resistant HeLa cells (Q28365365)

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1573083/fullTextXML

inferred from PubMed Central ID database lookup

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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Methods for thymidylate synthase pharmacodynamics: serial biopsy, free and total TS, FdUMP and dUMP, and H4PteGlu and CH2-H4PteGlu assays

2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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Elevation of thymidylate synthase following 5-fluorouracil treatment is prevented by the addition of leucovorin in murine colon tumors

2 June 2018

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2 June 2018

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Different mechanisms of acquired resistance to fluorinated pyrimidines in human colorectal cancer cells.

27 November 2018

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Desensitization and sensitization of cells to fluoropyrimidines with different antisenses directed against thymidylate synthase messenger RNA.

27 November 2018

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27 November 2018

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27 November 2018

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Inhibition of protein kinase C-alpha expression in human A549 cells by antisense oligonucleotides inhibits induction of intercellular adhesion molecule 1 (ICAM-1) mRNA by phorbol esters.

27 November 2018

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Thymidylate synthase expression: an independent prognostic factor for local recurrence, distant metastasis, disease-free and overall survival in rectal cancer

27 November 2018

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12 December 2020

Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed

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12 December 2020

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12 December 2020

Marked variation of thymidylate synthase and folylpolyglutamate synthetase gene expression in human colorectal tumors

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The role of thymidylate synthase in cellular regulation

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Anti-sense oligonucleotides directed against EGF-related growth factors enhance anti-proliferative effect of conventional anti-tumor drugs in human colon-cancer cells

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Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex

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Enhanced expression of thymidylate synthase may be of prognostic importance in advanced cervical cancer

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Thymidylate synthase expression in patients with colorectal carcinoma using a polyclonal thymidylate synthase antibody in comparison to the TS 106 monoclonal antibody

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12 December 2020

The thymidylate synthase inhibitor, ICI D1694, overcomes translational detainment of the enzyme

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12 December 2020

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12 December 2020

DNA damage and p53 induction do not cause ZD1694-induced cell cycle arrest in human colon carcinoma cells

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Chemosensitization and delayed androgen-independent recurrence of prostate cancer with the use of antisense Bcl-2 oligodeoxynucleotides

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